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Surrogate based continuous noninvasive blood pressure measurement

  • Alexandru-Gabriel Pielmus EMAIL logo , Jens Mühlstef , Erik Bresch , Martin Glos , Christiane Jungen , Stefan Mieke , Reinhold Orglmeister , Andreas Schulze , Birgit Stender , Verena Voigt and Sebastian Zaunseder
Published/Copyright: February 10, 2021
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Biomedical Engineering / Biomedizinische Technik
From the journal Biomedical Engineering / Biomedizinische Technik Volume 66 Issue 3

Abstract

Arterial blood pressure is one of the most often measured vital parameters in clinical practice. State-of-the-art noninvasive ABP measurement technologies have noticeable limitations and are mainly based on uncomfortable techniques of complete or partial arterial occlusion by cuffs. Most commonplace devices provide only intermittent measurements, and continuous systems are bulky and difficult to apply correctly for nonprofessionals. Continuous cuffless ABP measurements are still an unmet clinical need and a topic of ongoing research, with only few commercially available devices. This paper discusses surrogate-based noninvasive blood pressure measurement techniques. It covers measurement methods of continuously and noninvasively inferring BP from surrogate signals without applying external pressures, except for reference or initialization purposes. The BP is estimated by processing signal features, so called surrogates, which are modulated by variations of BP. Discussed techniques include well-known approaches such as pulse transit time and pulse arrival time techniques, pulse wave analysis or combinations thereof. Despite a long research history, these methods have not found widespread use in clinical and ambulatory practice, in part due to technical limitations and the lack of a standardized regulatory framework. This work summarizes findings from an invited workshop of experts in the fields covering clinical expertise, engineering aspects, commercialization and standardization issues. The goal is to provide an application driven outlook, starting with clinical needs, and extending to technical actuality. It provides an outline of recommended research directions and includes a detailed overview of clinical use case scenarios for these technologies, opportunities, and limitations.

Keywords: clinical; expert; guideline; NIBP; recommendation; workshop
Corresponding author: Alexandru-Gabriel Pielmus, Electronics and Medical Signal Processing, Technical University of Berlin, Einsteinufer 17, 10587Berlin, Germany, E-mail:

Acknowledgment

This paper is a result of a workshop organized by the section “Methods in Patient Monitoring” within the German Biomedical Society. Participants and their affiliation: Erik Bresch, Ph.D., Philips Research, Europe; Dr. rer. medic. Martin Glos, Charité-Universitätsmedizin Berlin, Deutschland; Dr. med. Christiane Jungen, Universitätsklinikum Hamburg-Eppendorf, Deutschland; Dr. Stefan Mieke, Physikalisch-Technische Bundesanstalt, Deutschland; Dr.-Ing. Jens Mühlsteff, Philips Research, Europe; Prof. Dr.-Ing. Reinhold Orglmeister, Technische Universität Berlin, Deutschland; Alexandru-Gabriel Pielmus, M.Sc., Technische Universität Berlin, Deutschland; Andreas Schulze, Philips Medizin Systeme GmbH, Deutschland; Birgit Stender, Drägerwerk AG & Co KGaA, Deutschland; Dr. med. Verena Voigt, Universitätsklinikum RWTH Aachen, Deutschland; Dr.-Ing. Sebastian Zaunseder, FH Dortmund/Technische Universität Dresden, Deutschland.

  1. Research funding: None declared.

  2. Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  3. Competing interests: Authors state no conflict of interest.

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Received: 2020-08-06
Accepted: 2020-12-28
Published Online: 2021-02-10
Published in Print: 2021-06-25

© 2021 Walter de Gruyter GmbH, Berlin/Boston

Articles in the same Issue

  1. Frontmatter
  2. Review
  3. Surrogate based continuous noninvasive blood pressure measurement
  4. Research Articles
  5. Smart automated heart health monitoring using photoplethysmography signal classification
  6. In vivo evaluation of two adaptive Starling-like control algorithms for left ventricular assist devices
  7. A patient-independent classification system for onset detection of seizures
  8. Prediction of salivary cortisol level by electroencephalography features
  9. Confocal laser microscopy without fluorescent dye in minimal-invasive thoracic surgery: an ex-vivo pilot study in lung cancer
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  11. Experimental and numerical investigations of fracture and fatigue behaviour of implant-supported bars with distal extension made of three different materials
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https://doi.org/10.1515/bmt-2020-0209
Keywords for this article
clinical; expert; guideline; NIBP; recommendation; workshop

Articles in the same Issue

  1. Frontmatter
  2. Review
  3. Surrogate based continuous noninvasive blood pressure measurement
  4. Research Articles
  5. Smart automated heart health monitoring using photoplethysmography signal classification
  6. In vivo evaluation of two adaptive Starling-like control algorithms for left ventricular assist devices
  7. A patient-independent classification system for onset detection of seizures
  8. Prediction of salivary cortisol level by electroencephalography features
  9. Confocal laser microscopy without fluorescent dye in minimal-invasive thoracic surgery: an ex-vivo pilot study in lung cancer
  10. Spinal cord segmentation and injury detection using a Crow Search-Rider optimization algorithm
  11. Experimental and numerical investigations of fracture and fatigue behaviour of implant-supported bars with distal extension made of three different materials
  12. Compression and tension behavior of the prosthetic foam materials polyurethane, EVA, Pelite™ and a combination of polyurethane and EVA: a preliminary study
  13. Evaluation of a novel stair-climbing transportation aid for emergency medical services
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