Adaptation of cardiovascular system stent implants
-
Vytautas Ostasevicius
,
Yahor Tretsyakou-Savich
Abstract
Time-consuming design and manufacturing processes are a serious disadvantage when adapting human cardiovascular implants as they cause unacceptable delays after the decision to intervene surgically has been made. An ideal cardiovascular implant should have a broad range of characteristics such as strength, viscoelasticity and blood compatibility. The present research proposes the sequence of the geometrical adaptation procedures and presents their results. The adaptation starts from the identification of a person’s current health status while performing abdominal aortic aneurysm (AAA) imaging, which is a point of departure for the mathematical model of a cardiovascular implant. The computerized tomography scan shows the patient-specific geometry parameters of AAA and helps to create a model using COMSOL Multiphysics software. The initial parameters for flow simulation are taken from the results of a patient survey. The simulation results allow choosing the available shape of an implant which ensures a non-turbulent flow. These parameters are essential for the design and manufacturing of an implant prototype which should be tested experimentally for the assurance that the mathematical model is adequate to a physical one. The article gives a focused description of competences and means that are necessary to achieve the shortest possible preparation of the adapted cardiovascular implant for the surgery.
Author Statement
Research funding: This research was funded by grants (No. SEN-10/15) from the Research Council of Lithuania.
Conflict of interest: The authors state no conflict of interest.
Informed consent: Informed consent is not applicable.
Ethical approval: Ethical approval is not applicable.
References
[1] Gee MW, Reeps C, Eckstein HH, Wall WA. Prestressing in finite deformation abdominal aortic aneurysm simulation. J Biomech 2009;42:1732–9.10.1016/j.jbiomech.2009.04.016Search in Google Scholar PubMed
[2] Zeinali-Davarani S, Baek S. Medical image-based simulation of abdominal aortic aneurysm growth. Mech Res Commun 2012;42:107–17.10.1016/j.mechrescom.2012.01.008Search in Google Scholar
[3] Moore JE. Biomechanical issues in endovascular device design. J Endovasc Ther 2009;16:I1–11.10.1583/08-2605.1Search in Google Scholar PubMed
[4] Howell BA, Kim T, Cheer A, Dwyer H, Saloner D, Chuter TA. Computational fluid dynamics within bifurcated abdominal aortic stent-grafts. J Endovasc Ther 2007;14:138–43.10.1177/152660280701400204Search in Google Scholar PubMed
[5] Meng X, Fu W, Zhang Y, Qiao A. Approaches to the reconstruction of numerical simulation oriented patient-specific model of aortic arch aneurysm. 2010 4th International Conference on Bioinformatics and Biomedical Engineering, Chengdu; 2010:1–4. doi: 10.1109/ICBBE.2010.5518183.10.1109/ICBBE.2010.5518183Search in Google Scholar
[6] He Y, Duraiswamy N, Frank AO, Moore JE Jr. Blood flow in stented arteries: a parametric comparison of strut design patterns in three dimensions. J Biomech Eng 2005;127: 637–47.10.1115/1.1934122Search in Google Scholar PubMed
[7] Chong CK, How TV, Black RA, Shortland AP, Harris PL. Development of a simulator for endovascular repair of abdominal aortic aneurysms. Ann Biomed Eng 1998;26:798–802.10.1114/1.66Search in Google Scholar PubMed
[8] Chuter TA. Durability of endovascular infrarenal aneurysm repair: when does late failure occur and why? Semin Vasc Surg 2009;22:102–10.10.1053/j.semvascsurg.2009.04.008Search in Google Scholar PubMed
[9] Chuter TA. Stent-graft design: the good, the bad and the ugly. Cardiovasc Surg 2002;10:7–13.10.1016/S0967-2109(01)00120-XSearch in Google Scholar PubMed
[10] Molony DS, Kavanagh EG, Madhavan P, Walsh MT, McGloughlin TM. A computational study of the magnitude and direction of migration forces in patient-specific abdominal aortic aneurysm stent-grafts. Eur J Vasc Endovasc Surg 2010;40:332–9.10.1016/j.ejvs.2010.06.001Search in Google Scholar PubMed
[11] Avgerinos ED, Dalainas I, Kakisis J, Moulakakis K, Giannakopoulos T, Liapis CD. Endograft accommodation on the aortic bifurcation: an overview of anatomical fixation and implications for long-term stent-graft stability. J Endovasc Ther 2011;18:462–70.10.1583/11-3411.1Search in Google Scholar PubMed
[12] Veerapen R, Dorandeu A, Serre I, Berthet JP, Marty-Ane CH, Mary H, et al. Improvement in proximal aortic endograft fixation: an experimental study using different stent-grafts in human cadaveric aortas. J Endovasc Ther December 2003;10:1101–9.10.1177/152660280301000613Search in Google Scholar PubMed
[13] Greenberg K, Eagleton MJ, Clair DG. Late conversion of aortic stent grafts. J Vasc Surg 2009;49:589–95.10.1016/j.jvs.2008.10.020Search in Google Scholar PubMed
[14] Wendt JF. Computational fluid dynamics. 3rd ed. 15c. Berlin Heidelberg: Springer-Verlag; 2009.10.1007/978-3-540-85056-4Search in Google Scholar
[15] Tennekes H, Lumley JL. A first course in turbulence. 14th ed. Cambridge, MA: MIT Press; 1992.Search in Google Scholar
[16] Taylor TW, Yamaguchi T. Three-dimensional simulation of blood flow in an abdominal aortic aneurysm – steady and unsteady flow cases. J Biomech 1994;116:89–97.10.1115/1.2895709Search in Google Scholar PubMed
[17] Crane CO. Flow of fluids through valves, fittings, and pipe. 25th ed. Stamford, CT, USA: Crane CO; 1988.Search in Google Scholar
[18] White FM. Fluid Mechanics. 7th ed. New York: McGraw-Hill; 2011.Search in Google Scholar
[19] Rousseau H, Elaassar O, Marcheix B, Cron C, Chabbert V, Combelles S, et al. The role of stent-grafts in the management of aortic trauma. Cardiovasc Intervent Radiol 2012;35:2–14.10.1007/s00270-011-0135-9Search in Google Scholar PubMed
[20] Zarins CK, Taylor CA. Endovascular device design in the future: transformation from trial and error to computational design. J Endovasc Ther 2009;16:I12–21.10.1583/09-2912LR.1Search in Google Scholar PubMed
[21] Gao F, Watanabe M, Matsuzawa T. Stress analysis in a layered aortic arch model under pulsatile blood flow. BioMed Eng OnLine 2006;5:25.10.1186/1475-925X-5-25Search in Google Scholar PubMed PubMed Central
[22] Masoumi Khalil Abad E, Pasini D, Cecere R. Shape optimization of stress concentration-free lattice for self-expandable Nitinol stent-grafts. J Biomech 2012;45:1028–35.10.1016/j.jbiomech.2012.01.002Search in Google Scholar PubMed
[23] Zilla P, Bezuidenhout D, Human P. Prosthetic vascular grafts: wrong models, wrong questions and no healing. Biomaterials 2007;28:5009–27.10.1016/j.biomaterials.2007.07.017Search in Google Scholar PubMed
[24] Singh C, Wong CS, Wang X. Medical textiles as vascular implants and their success to mimic natural arteries. J Funct Biomat 2015;6:500–25.10.3390/jfb6030500Search in Google Scholar PubMed PubMed Central
©2018 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Frontmatter
- Editorial
- The role of textile engineering in regenerative medicine
- Research articles
- Fibrous composite material for textile heart valve design: in vitro assessment
- Electro-spun PLA-PEG-yarns for tissue engineering applications
- Preparation, characterization and blood compatibility assessment of a novel electrospun nanocomposite comprising polyurethane and ayurvedic-indhulekha oil for tissue engineering applications
- Three-dimensional bioglass-collagen-phosphatidylserine scaffolds designed with functionally graded structure and mechanical features
- Differential mineralization of human dental pulp stem cells on diverse polymers
- Heart valves from polyester fibers: a preliminary 6-month in vivo study
- Adaptation of cardiovascular system stent implants
- Synthesizing selenium- and silver-substituted hydroxyapatite-based bone grafts and their effects on antibacterial efficiency and cell viability
- Long-term recording performance and biocompatibility of chronically implanted cylindrically-shaped, polymer-based neural interfaces
- Morphology and contractile gene expression of adipose-derived mesenchymal stem cells in response to short-term cyclic uniaxial strain and TGF-β1
- A novel ceramic tibial component is as safe as its metal counterpart
- Short communication
- Hybrid textile heart valve prosthesis: preliminary in vitro evaluation
Articles in the same Issue
- Frontmatter
- Editorial
- The role of textile engineering in regenerative medicine
- Research articles
- Fibrous composite material for textile heart valve design: in vitro assessment
- Electro-spun PLA-PEG-yarns for tissue engineering applications
- Preparation, characterization and blood compatibility assessment of a novel electrospun nanocomposite comprising polyurethane and ayurvedic-indhulekha oil for tissue engineering applications
- Three-dimensional bioglass-collagen-phosphatidylserine scaffolds designed with functionally graded structure and mechanical features
- Differential mineralization of human dental pulp stem cells on diverse polymers
- Heart valves from polyester fibers: a preliminary 6-month in vivo study
- Adaptation of cardiovascular system stent implants
- Synthesizing selenium- and silver-substituted hydroxyapatite-based bone grafts and their effects on antibacterial efficiency and cell viability
- Long-term recording performance and biocompatibility of chronically implanted cylindrically-shaped, polymer-based neural interfaces
- Morphology and contractile gene expression of adipose-derived mesenchymal stem cells in response to short-term cyclic uniaxial strain and TGF-β1
- A novel ceramic tibial component is as safe as its metal counterpart
- Short communication
- Hybrid textile heart valve prosthesis: preliminary in vitro evaluation
