Three-dimensional image fusion across PET+MRI modalities based on the approach of characteristic coregistration
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Matthew Jian-qiao Peng
Abstract
Background and aims: Because there is no complete three-dimensional (3D) hybrid detector integrated PET+MRI internationally, this study aims to investigate a registration approach for a two-dimensional (2D) hybrid based on characteristic localization to achieve a 3D fusion from the images of PET and MRI as a whole.
Methods: A cubic-oriented scheme of “9-point and 3-plane” for a coregistration design was verified to be geometrically practical. Through 3D reconstruction and virtual dissection, human internal feature points were sorted to combine with preselected external feature points for matching process. By following the procedure of feature extraction and image mapping, the processes of “picking points to form planes” and “picking planes for segmentation” were executed. Eventually, the image fusion was implemented at the real-time workstation Mimics based on auto-fuse techniques called “information exchange” and “signal overlay”.
Results: A complementary 3D image across PET+MRI modalities, which simultaneously present metabolic activities and anatomic structures, was created with a detectable rate of 56%. This is equivalent to the detectable rate of PET+CT or MRI+CT with no statistically significant difference, and it facilitates a 3D vision that is not yet functional for 2D hybrid imaging.
Conclusions: This cross-modality fusion is doubtless an essential complement for the existing toolkit of a 2D hybrid device. Thus, it would potentially improve the efficiency of diagnosis and therapy for oncology.
©2012 by Walter de Gruyter Berlin Boston
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Artikel in diesem Heft
- Masthead
- Masthead
- Review
- Diagnosis, prevention and treatment of accidental and perioperative hypothermia
- Research Articles
- Development of a computer-based automated pure tone hearing screening device: a preliminary clinical trial
- Control of a HexaPOD treatment couch for robot-assisted radiotherapy
- Mechanical testing of an absorbable hybrid fusion cage for the cervical spine
- Determination of the frictional coefficient of the implant-antler interface: experimental approach
- Section plane selection influences the results of histomorphometric studies: the example of dental implants
- Decomposition of fractionated local electrograms using an analytic signal model based on sigmoid functions
- Determination of fetal heart rate from abdominal signals: evaluation of beat-to-beat accuracy in relation to the direct fetal electrocardiogram
- Feature selection using binary particle swarm optimization and support vector machines for medical diagnosis
- Interoperability optimization in healthcare collaboration networks
- Three-dimensional image fusion across PET+MRI modalities based on the approach of characteristic coregistration
