From transcription to translation: new insights in the structure and function of Argonaute protein

Corinna Giorgi; Carlo Cogoni; Caterina Catalanotto

doi:10.1515/bmc-2012-0024

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From transcription to translation: new insights in the structure and function of Argonaute protein

Corinna Giorgi
Corinna Giorgi obtained her PhD in Genetics and Molecular Biology in 2002 at the University of Rome “La Sapienza”, working in the laboratory of Prof. Irene Bozzoni. She then joined Prof. Melissa Laboratory as a Howard Hughes postdoctoral fellow in the Biochemistry Department of Brandeis University (MA) in the USA. Since 2007, she joined EBRI, the European Brain Research Institute in Rome, initially in Prof. Carlo Cogoni’s laboratory, and currently as a project leader. In 2009 she was awarded a Marie Curie International Reintegration Grant. The overarching focus of her research is to understand how post-transcriptional regulation of gene expression, particularly at the level of mRNA metabolism, participates in modulating neuronal functions.
, Carlo Cogoni
Carlo Cogoni studied Biology at the University of Rome, Italy. He was appointed Assistant Professor and Group Leader at the European Brain Research Institute in Rome. He is currently Associate Professor at the Dept. of Biotechnology and Haematology, Sapienza University of Rome. He pioneered the studies on the dissection of the silencing machinery by using the fungus Neurospora crassa as a model system. More recently, his research interests focus on the role of the RNA-mediated gene silencing machinery in neuronal cells.
and Caterina Catalanotto
Caterina Catalanotto received her PhD in “Human Biology: Cellular and Molecular Bases” from the University of Rome “Sapienza” in 2003. She became assistant professor at the University of Rome “Sapienza” in the Department of Cellular Biotechnology and Haematology in 2008. Her research program is focused on microRNAs and Argonaute proteins.

Published/Copyright: August 31, 2012

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From the journal BioMolecular Concepts Volume 3 Issue 6

Received: 2012-6-5

Accepted: 2012-7-20

Published Online: 2012-08-31

Published in Print: 2012-12-01

Articles in the same Issue

https://doi.org/10.1515/bmc-2012-0024

Keywords for this article

Argonaute; gene expression; GW182; miRNA