The source of Helicobacter pylori infection in the neonatal period
-
Maria Elisabetta Baldassarre
Abstract
Aims: To investigate the transmission of Helicobacter pylori in the perinatal period.
Methods: H. pylori status of 180 women was preliminarily screened by serology and stool antigen test (SAT) within the fourth day after delivery and a positive value was confirmed by 13C-urea breath test. Infants were analyzed by SAT at 1, 6, 12 and 18 months of age. H. pylori status was also investigated in the medical and paramedical staff of the Neonatology Unit.
Results: H. pylori infection was found in 34.4% of the women. At the 1st month of age, 5 out of 172 newborns (2.9%) were H. pylori positive by SAT. Three out of the five positive infants were born to H. pylori non-infected mothers. Formula feeding (P=0.02) and admission in intermediate-risk neonatal unit (P=0.01) were significantly related to a positive H. pylori result. Medical and paramedical staff of the neonatology unit was found H. pylori positive in 34.8% of cases. All five H. pylori positive children spontaneously cleared the infection.
Conclusions: Perinatal H. pylori SAT positive status is low in our area, and it may be found both in infants from infected or non-infected mothers. Formula feeding and admission in intermediate-risk neonatal unit appear to be related with H. pylori infection.
©2009 by Walter de Gruyter Berlin New York
Articles in the same Issue
- Immunologic and infectious consequences of immediate versus delayed umbilical cord clamping in premature infants: A prospective, randomized, controlled study
- Opinion paper
- The Groningen Protocol: Is it necessary? Is it scientific? Is it ethical?
- Original articles – Obstetrics
- Maternal visfatin concentration in normal pregnancy
- Visfatin in human pregnancy: maternal gestational diabetes vis-à-vis neonatal birthweight
- Values of amniotic fluid index in cases of preterm premature rupture of membranes
- Access to level III perinatal care for pregnancies of very short duration (<32 weeks)
- Statistical model predicting a short duration to birth in women with preterm labor at 22–35 weeks' gestation: the importance of large vaginal Gram-positive rods
- Pregnant women's perception of cesarean section on demand
- Adiponectin induced placental cell apoptosis could be mediated via the ADIPOR1-receptor in pre-eclampsia with IUGR
- The effect of bilateral pelvic neurectomy on cervical ripening in pregnant rats
- Original article – Fetus
- Evaluation of normal neurological development of human fetuses from 21 to 30 weeks' gestation through fetal auditory evoked response
- Do fetal heart rate deceleration patterns during labor differ between various umbilical cord abnormalities?
- Original articles – Newborn
- Immunologic and infectious consequences of immediate versus delayed umbilical cord clamping in premature infants: A prospective, randomized, controlled study
- The source of Helicobacter pylori infection in the neonatal period
- Neonatal phrenic nerve injury due to traumatic delivery
- Developmental alterations of the prefrontal cerebral cortex in sudden unexplained perinatal and infant deaths
- Letter to the editor
- Palivizumab for prophylaxis of RSV infection: five epidemic seasons' experience on adverse effects (2002–2007)
- Prevention of intrauterine growth restriction: Are there no effective methods available?
- Congress Calender
- 10.1515/JPM.2009.073
Articles in the same Issue
- Immunologic and infectious consequences of immediate versus delayed umbilical cord clamping in premature infants: A prospective, randomized, controlled study
- Opinion paper
- The Groningen Protocol: Is it necessary? Is it scientific? Is it ethical?
- Original articles – Obstetrics
- Maternal visfatin concentration in normal pregnancy
- Visfatin in human pregnancy: maternal gestational diabetes vis-à-vis neonatal birthweight
- Values of amniotic fluid index in cases of preterm premature rupture of membranes
- Access to level III perinatal care for pregnancies of very short duration (<32 weeks)
- Statistical model predicting a short duration to birth in women with preterm labor at 22–35 weeks' gestation: the importance of large vaginal Gram-positive rods
- Pregnant women's perception of cesarean section on demand
- Adiponectin induced placental cell apoptosis could be mediated via the ADIPOR1-receptor in pre-eclampsia with IUGR
- The effect of bilateral pelvic neurectomy on cervical ripening in pregnant rats
- Original article – Fetus
- Evaluation of normal neurological development of human fetuses from 21 to 30 weeks' gestation through fetal auditory evoked response
- Do fetal heart rate deceleration patterns during labor differ between various umbilical cord abnormalities?
- Original articles – Newborn
- Immunologic and infectious consequences of immediate versus delayed umbilical cord clamping in premature infants: A prospective, randomized, controlled study
- The source of Helicobacter pylori infection in the neonatal period
- Neonatal phrenic nerve injury due to traumatic delivery
- Developmental alterations of the prefrontal cerebral cortex in sudden unexplained perinatal and infant deaths
- Letter to the editor
- Palivizumab for prophylaxis of RSV infection: five epidemic seasons' experience on adverse effects (2002–2007)
- Prevention of intrauterine growth restriction: Are there no effective methods available?
- Congress Calender
- 10.1515/JPM.2009.073
