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Neonatal phrenic nerve injury due to traumatic delivery

  • Claire A.I. Stramrood , Cornelia A. Blok , David C. van der Zee and Leo J. Gerards
Published/Copyright: February 9, 2009

Abstract

Aims: To describe the clinical course of infants recovering spontaneously from diaphragmatic paralysis due to perinatal phrenic nerve injury as well as those that underwent plication of the diaphragm.

Methods: Between 1990 and 2006, 14 newborns admitted to the Neonatal Intensive Care Unit (NICU) of the Wilhelmina Children's Hospital in Utrecht, The Netherlands, were diagnosed with diaphragmatic paralysis due to obstetric phrenic nerve injury. The clinical and follow-up data were studied retrospectively.

Results: Four infants recovered spontaneously and could be weaned from mechanical ventilation within nine days without further treatment. Plication of the diaphragm was performed in 10 infants because of failure to wean from ventilatory support or serious persistent respiratory distress. Time between birth and plication ranged from 10 to 51 days, with a median of 19 days. Satisfactory respiratory outcome was achieved in 86% of the cases.

Conclusions: The minority of infants suffering from diaphragmatic paralysis due to perinatal phrenic nerve injury recovers spontaneously. Infants who fail to wean from ventilatory support and undergo early plication have a quick recovery and can be extubated successfully within a few days.


Corresponding author: Cornelia A. Blok Department of Neonatology Room KE.04.123.1 Wilhelmina Children's Hospital University Medical Center Utrecht PO BOX 85090 3508 AB Utrecht The Netherlands Tel.: +31-88-7554545 Fax: +31-88-7555320

Received: 2008-6-4
Revised: 2008-9-19
Accepted: 2008-9-29
Published Online: 2009-02-09
Published Online: 2009-02-09
Published in Print: 2009-05-01

©2009 by Walter de Gruyter Berlin New York

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