Pregnancy outcome of women who developed proteinuria in the absence of hypertension after mid-gestation
-
Mamoru Morikawa
Abstract
Objective: To characterize the clinical features of women with singleton pregnancies who develop proteinuria in the absence of hypertension after mid-gestation.
Methods: Seventy-nine women who developed proteinuria and/or hypertension at and after 20 weeks of gestation were reviewed, focusing on the gestational week at which significant proteinuria (>0.3 g/day) and/or hypertension developed.
Results: Thirty-seven (47%) women exhibited new-onset proteinuria (>0.3 g/day) in the absence of hypertension, 33 (42%) exhibited new-onset hypertension in the absence of proteinuria, and 9 (11%) exhibited both proteinuria and hypertension. Nineteen (51%) of 37 women who exhibited new proteinuria in the absence of hypertension and 5 (15%) of 33 women who exhibited new hypertension in the absence of proteinuria progressed to preeclampsia (P=0.002). Among women who exhibited new proteinuria, 10 (77%) out of 13 women and 9 (38%) out of 24 women who developed proteinuria at <32 weeks and ≥32 weeks, respectively, progressed to preeclampsia (P=0.022).
Conclusions: Women with new-onset proteinuria in the absence of hypertension may be more likely to progress to preeclampsia than women with a presumptive diagnosis of gestational hypertension, and the likelihood of progression may be significantly greater among women with earlier presentation.
©2008 by Walter de Gruyter Berlin New York
Artikel in diesem Heft
- Original articles – Obstetrics
- Premature labor: a state of platelet activation?
- Soluble receptor for advanced glycation end products (sRAGE) and endogenous secretory RAGE (esRAGE) in amniotic fluid: modulation by infection and inflammation
- Detection of feto-maternal infection/inflammation by the soluble receptor for advanced glycation end products (sRAGE): results of a pilot study
- Weight gain in pregnancy according to maternal height and weight
- A randomized trial of tight vs. less tight control of mild essential and gestational hypertension in pregnancy
- Pregnancy outcome of women who developed proteinuria in the absence of hypertension after mid-gestation
- Anxiety symptoms during late pregnancy and early parenthood following assisted reproductive technology
- Original article – Fetus
- Human fetal heart rate variability-characteristics of autonomic regulation in the third trimester of gestation
- Original articles – Newborn
- Bronchopulmonary dysplasia and early prophylactic inhaled nitric oxide in preterm infants: current concepts and future research strategies in animal models
- Side effects of angiotensin converting enzyme inhibitor (captopril) in newborns and young infants
- Letters to the editor
- Mirror syndrome due to coxackie B virus associated to maternal peripartum cardiomyopathy
- Non-cardiogenic lung edema in a woman treated with atosiban for preterm labor
- Commentary: A case of non-cardiogenic lung edema in a woman treated with atosiban for preterm labor
- Congress Calendar
- 10.1515/JPM.2008.095
- Erratum
- Total body water in small- and appropriate - for gestational age newborns
- Announcement
- Calling European Pediatric Research Networks
- WAPM-Newsletter
- WAPM-Newsletter No 1/2008
Artikel in diesem Heft
- Original articles – Obstetrics
- Premature labor: a state of platelet activation?
- Soluble receptor for advanced glycation end products (sRAGE) and endogenous secretory RAGE (esRAGE) in amniotic fluid: modulation by infection and inflammation
- Detection of feto-maternal infection/inflammation by the soluble receptor for advanced glycation end products (sRAGE): results of a pilot study
- Weight gain in pregnancy according to maternal height and weight
- A randomized trial of tight vs. less tight control of mild essential and gestational hypertension in pregnancy
- Pregnancy outcome of women who developed proteinuria in the absence of hypertension after mid-gestation
- Anxiety symptoms during late pregnancy and early parenthood following assisted reproductive technology
- Original article – Fetus
- Human fetal heart rate variability-characteristics of autonomic regulation in the third trimester of gestation
- Original articles – Newborn
- Bronchopulmonary dysplasia and early prophylactic inhaled nitric oxide in preterm infants: current concepts and future research strategies in animal models
- Side effects of angiotensin converting enzyme inhibitor (captopril) in newborns and young infants
- Letters to the editor
- Mirror syndrome due to coxackie B virus associated to maternal peripartum cardiomyopathy
- Non-cardiogenic lung edema in a woman treated with atosiban for preterm labor
- Commentary: A case of non-cardiogenic lung edema in a woman treated with atosiban for preterm labor
- Congress Calendar
- 10.1515/JPM.2008.095
- Erratum
- Total body water in small- and appropriate - for gestational age newborns
- Announcement
- Calling European Pediatric Research Networks
- WAPM-Newsletter
- WAPM-Newsletter No 1/2008
