Does raising the glucose challenge test threshold impact birthweight in Asian gravidas?
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Nikki Koklanaris
Abstract
Objective: Some authors suggest a glucose challenge test (GCT) threshold of 150 mg/dL in Asian gravidas. The impact of such a policy on outcomes is unknown.
Study Design: A retrospective cohort of 1705 Asian gravidas. Subjects (n=95) had a GCT of 140–150 mg/dL and underwent a 3-h glucose tolerance test (GTT). Matched controls (n=190) had a GCT of <140 mg/dL. Birthweight was the primary outcome and the secondary outcomes were cesarean delivery (CD) rate and macrosomia.
Results: Eight subjects (11.9%) had gestational diabetes mellitus (GDM); none had GTT fasting values of >90 mg/dL. Mean birthweight was 3282 g in the subjects and 3238 g in the controls (P=0.39). There were no significant differences in the secondary outcomes.
Conclusion: Compared with controls, study patients did not deliver significantly larger infants. However, raising the GCT threshold would have missed 8 subjects (11.9%) with GDM. Raising the GCT threshold to 150 mg/dL in Asian gravidas may unacceptably lower the sensitivity of the screening test.
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©2007 by Walter de Gruyter Berlin New York
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Artikel in diesem Heft
- To all readers, authors and subscribers
- The relationship between periodontal disease, bacterial vaginosis, and preterm birth
- Does raising the glucose challenge test threshold impact birthweight in Asian gravidas?
- Puerperal complications following elective cesarean sections for twin pregnancies
- Fortified mineral water improves folate status and decreases plasma homocysteine concentration in pregnant women
- Milk iron content in breast-feeding mothers after administration of intravenous iron sucrose complex
- Uteroplacental circulation, preeclampsia, and maternal abdominal aortic stiffness in normal and compromised pregnancies
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- Reference intervals for the cross sectional area of the umbilical cord during gestation
- The combined effect of betamethasone and ritodrine on the middle cerebral artery in low risk third trimester pregnancies
- Association between peak serum bilirubin and severity of respiratory distress syndrome in infants of less than 30 weeks' gestation
- Ranitidine and late-onset sepsis in the neonatal intensive care unit
- Outcome of infants born at 21–28 weeks' gestation in an inner-city hospital over an eight-year period
- Detection rate of Helicobacter pylori stool antigen in newborn infants and small children
- The potential role of high or low birthweight as risk factor for adult schizophrenia
- Multiple vascular accidents: Pentalogy of Cantrell in one twin with left sided colonic atresia in the second twin
- Solitary hepatic lymphangioma in an infant
- Spontaneous twin pregnancy in a 56-year-old primipara
- Fetal behavior analyzed by ultrasonic actocardiogram in cases with central nervous system lesions
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