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Umbilical artery pulsatility index: reliability at different sampling sites

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Published/Copyright: September 11, 2006
Journal of Perinatal Medicine
From the journal Volume 34 Issue 5

Abstract

Objectives: To analyse the inter-observer and inter-artery reliability of the umbilical artery (UA) pulsatility index (PI) at different sampling sites.

Methods: One hundred consecutive singleton pregnancies between 24 and 40 weeks were included. The PI was calculated by two independent operators from both umbilical arteries at the placental end, at a free-floating loop and at the perivesical segment. Reliability analyses were performed between observers and between arteries at each sampling site.

Results: The mean percentage of PI difference between arteries was 15.2, 14.5 and 22% at the placental end, free-loop and perivesical site, respectively. The Intraclass correlation coefficients at each site were 0.51, 0.59 and 0.67, respectively. Whereas about 20% of cases showed a percentage of PI difference between arteries greater than 20% at free-loop and placental end sites, and at the perivesical site this figure was 45%.

Conclusions: The perivesical sampling site for UA PI calculation is more reliable than at a free-floating loop, albeit without significance, and is significantly more reliable than at the placental end of the umbilical cord. Since discordances in PI between both arteries are more pronounced at the perivesical site, it seems mandatory to evaluate both arteries in this segment.

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Corresponding author: Francesc Figueras Retuerta, MD Obstetrics Department Hospital Clinic Sabino de Arana, 1 08034 Barcelona, Spain Tel.: +34-932275600 Fax: +34-932275605

References

1. Abramowicz JS, SL Warsof, J Arrington, DL Levy: Doppler analysis of the umbilical artery. The importance of choosing the placental end of the cord. J Ultrasound Med8 (1989) 219Search in Google Scholar

2. Acharya G, T Wilsgaard, GK Berntsen, JM Maltau, T Kiserud: Reference ranges for serial measurements of blood velocity and pulsatility index at the intra-abdominal portion, and fetal and placental ends of the umbilical artery. Ultrasound Obstet Gynecol26 (2005) 162Search in Google Scholar

3. Bland JM, DG Altman: Applying the right statistics: analyses of measurement studies. Ultrasound Obstet Gynecol22 (2003) 85Search in Google Scholar

4. Degani S, RM Lewinsky, H Berger, D Spiegel: Sonographic estimation of umbilical coiling index and correlation with Doppler flow characteristics. Obstet Gynecol86 (1995) 990Search in Google Scholar

5. Di Naro E, F Ghezzi, L Raio, M Franchi, V D'Addario: Umbilical cord morphology and pregnancy outcome. Eur J Obstet Gynecol Reprod Biol96 (2001) 150Search in Google Scholar

6. Fleiss J: Statistical methods for rates and proportions (2nd edn). New York, John Wiley, 1981Search in Google Scholar

7. Forouzan I, AW Cohen, P Arger: Measurement of systolic-diastolic ratio in the umbilical artery by continuous-wave and pulsed-wave Doppler ultrasound: comparison at different sites. Obstet Gynecol77 (1991) 209Search in Google Scholar

8. Gudmundsson S, F Fairlie, G Lingman, K Marsal: Recording of blood flow velocity waveforms in the uteroplacental and umbilical circulation: reproducibility study and comparison of pulsed and continuous wave Doppler ultrasonography. J Clin Ultrasound18 (1990) 97Search in Google Scholar

9. Kay HH, BA Carroll, JD Bowie, AP Killam, BS Hertzberg: Nonuniformity of fetal umbilical systolic/diastolic ratios as determined with duplex Doppler sonography. J Ultrasound Med8 (1989) 417Search in Google Scholar

10. Luiz RR, AJ Costa, PL Kale, GL Werneck: Assessment of agreement of a quantitative variable: a new graphical approach. J Clin Epidemiol56 (2003) 963Search in Google Scholar

11. Maulik D, P Yarlaggada: In vitro validation of Doppler waveform indices, in Doppler ultrasound measurements of maternal-fetal hemodynamics. Maulik D, (ed). Perinatology Press, New York, 1987, 257Search in Google Scholar

12. Maulik D, AP Yarlagadda, JP Youngblood, L Willoughby: Components of variability of umbilical arterial Doppler velocimetry – a prospective analysis. Am J Obstet Gynecol160 (1989) 1406; discussion 1409–12Search in Google Scholar

13. Mehalek KE, J Rosenberg, GS Berkowitz, U Chitkara, RL Berkowitz: Umbilical and uterine artery flow velocity waveforms. Effect of the sampling site on Doppler ratios. J Ultrasound Med8 (1989) 171Search in Google Scholar

14. Nienhuis SJ, JM van Vugt, HJ Hoogland, CJ Ruissen, J de Haan: Interexaminer variability of fetal Doppler velocity waveforms. Gynecol Obstet Invest25 (1988) 152Search in Google Scholar

15. Predanic M, J Kolli, P Yousefzadeh, J Pennisi: Disparate blood flow patterns in parallel umbilical arteries. Obstet Gynecol91 (5 Pt 1) (1998) 75710.1097/00006250-199805000-00022Search in Google Scholar

16. Pretorius DH, C Chau, DM Poeltler, A Mendoza, VA Catanzarite, KA Hollenbach: Placental cord insertion visualization with prenatal ultrasonography. J Ultrasound Med15 (1996) 585Search in Google Scholar

17. Raio L, F Ghezzi, E di Naro, M Franchi, D Balestreri, P Durig, H Schneider: In-utero characterization of the blood flow in the Hyrtl anastomosis. Placenta22 (2001) 597Search in Google Scholar

18. Ruissen CJ, MM von Drongelen, HJ Hoogland, W Jager, AP Hoeks: Characteristics of the umbilical artery velocity waveform as function of measurement site. Gynecol Obstet Invest30 (1990) 212Search in Google Scholar

19. Schulman H, A Fleischer W Stern, G Farmakides, N Jagani, P Blattner: Umbilical velocity wave ratios in human pregnancy. Am J Obstet Gynecol148 (1984) 985Search in Google Scholar

20. Skoll MA, JC Fouron, SE Sonesson, H Nyctelius, M Lessard, SP Drblik: Doppler velocimetric indices from the abdominal and placental ends of the umbilical artery of growth-restricted fetuses. J Clin Ultrasound25 (1997) 421Search in Google Scholar

21. Sonesson SE, JC Fouron, SP Drblik, C Tawile, M Lessard, A Skoll, MC Guertin, GR Ducharme: Reference values for Doppler velocimetric indices from the fetal and placental ends of the umbilical artery during normal pregnancy. J Clin Ultrasound21 (1993) 317Search in Google Scholar

22. Vieyres P, A Durand, F Patat, P Descamps, JM Gregoire, D Pourcelot, L Pourcelot: Influence of the measurement location on the resistance index in the umbilical arteries: a hemodynamic approach. J Ultrasound Med10 (1991) 671Search in Google Scholar

23. Walter SD, M Eliasziw, A Donner: Sample size and optimal designs for reliability studies. Stat Med17 (1998) 101Search in Google Scholar

Published Online: 2006-09-11
Published in Print: 2006-10-01

©2006 by Walter de Gruyter Berlin New York

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