Startseite Medizin Normal standards for fetal neurobehavioral developments – longitudinal quantification by four-dimensional sonography
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Normal standards for fetal neurobehavioral developments – longitudinal quantification by four-dimensional sonography

  • Asim Kurjak , Wiku Andonotopo , Tomislav Hafner , Aida Salihagic Kadic , Milan Stanojevic , Guillermo Azumendi , Badreldeen Ahmed , Jose M. Carrera und J.M. Troyano
Veröffentlicht/Copyright: 11. Januar 2006

Abstract

Aim: To construct normal standards for fetal neurobehavioral development using longitudinal observations through all trimesters by four-dimensional sonography.

Subject and methods: A group of 100 healthy normal singleton pregnancies were recruited for longitudinal 4D US examinations to evaluate fetal neurodevelopmental parameters between 7 to 40 weeks' gestation. Variables of maternal and fetal characteristics including gestational age, eight fetal movements patterns in the first trimester and 14 parameters of fetal movement and fetal facial expression patterns recorded thereafter for the construction of fetal neurological charts.

Results: Measurement of 7 parameters in the first trimester and 11 parameters in the second and third trimesters correlated with gestational age (P<0.05). Those parameters have been followed longitudinally through all trimesters and showed increasing frequency of fetal movements during the first trimester. A tendency towards decreased frequency of facial expressions and movement patterns with increasing gestational age from second to third trimesters has been noticed.

Conclusion: With 4D sonography, it is possible to quantitatively assess normal neurobehavioral development. There is urgent need for further multicentric studies until a sufficient degree of normative data is available and the predictive validity of the specific relationship between fetal neurobehavior and child developmental outcome is better established.

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Corresponding author: Wiku Andonotopo, MD Department of Obstetrics and Gynecology Medical School, University of Zagreb Sveti Duh Hospital Sveti Duh 64 Zagreb/Croatia Tel.:+385 91 8895288 Fax:+385 1 3745534

References

1 Andonotopo W, A Kurjak, G Azumendi: Ultrasound studies on early pregnancy. In: Kurjak A, JM Carrera (eds): Atlas of Clinical Application of Ultrasound in Obstetrics and Gynecology. Jaypee Brothers Medical Publishers, New Delhi 2005 (In Press)Suche in Google Scholar

2 Andonotopo W, A Kurjak, MI Kosuta: Behavioral of anencephalic fetus studied by 4D sonography. J Matern Fetal Neonatal Med17 (2005) 165Suche in Google Scholar

3 Andonotopo W, M Medic, A Salihagic-Kadic, D Milenkovic, N Maiz, E Scazzocchio: The assessment of embryonic and fetal neurodevelopment in early pregnancy: comparison between 2D and 4D sonographic scanning. J Perinat Med (In Press)Suche in Google Scholar

4 Andonotopo W, M Stanojevic, A Kurjak, G Azumendi, JM Carrera: Assessment of fetal behavior and general movements by four-dimensional sonography. Ultrasound Rev Obstet Gynecol4 (2004) 103Suche in Google Scholar

5 Azumendi G, A Kurjak: Three-dimensional and four-dimensional sonography in the study of the fetal face. Ultrasound Rev Obstet Gynecol3 (2003) 160Suche in Google Scholar

6 Azumendi G, JB Arenas, W Andonotopo, A Kurjak: Three dimensional sonoembriology. In: Kurjak A, JB Arenas (eds): Textbook of Transvaginal Sonography. Taylor & Francis, London 2005, pp 407Suche in Google Scholar

7 Azumendi G, A Kurjak, JM Carrera, W Andonotopo, E Scazzocchio: 3D and 4D sonography in the evaluation of normal and abnormal fetal facial expression. In: Kurjak A, JM Carrera (eds): Atlas of Clinical Application of Ultrasound in Obstetrics and Gynecology. Jaypee Brothers Medical Publishers, New Delhi 2005 (In Press)Suche in Google Scholar

8 Carrera JM: Fetal ultrasonography: the first 40 years. Ultrasound Rev Obstet Gynecol4 (2004) 14110.3109/14722240400023537Suche in Google Scholar

9 Cioni G, HF Prechtl, F Ferrari, PB Paolicelli, C Einspieler, MF Roversi: Which better predicts later outcome in full term infants: quality of general movements or neurological examination? Early Hum Dev50 (1997) 71Suche in Google Scholar

10 de Vries JIP, GHA Visser, HFR Prechtl: Fetal motility in the first half of the pregnancy. In: Prechtl HFR (Ed): Continuity of Neural Functions from Prenatal to Postnatal Life. Lippincott, Philadelphia, PA 1984, pp 44Suche in Google Scholar

11 de Vries JIP, GHA Visser, HFR Prechtl: The emergence of fetal behaviour I. Qualitative aspects. Early Human Dev7 (1982) 301Suche in Google Scholar

12 de Vries JIP, GHA Visser, HFR Prechtl: The emergence of fetal behaviour II. Quantitative aspects. Early Human Dev12 (1985) 99Suche in Google Scholar

13 Di Pietro JA: Neurobehavioral assessment before birth. Mental retardation and developmental disabilities11(2005) 410.1002/mrdd.20047Suche in Google Scholar

14 Einspieler C, HFR Prechtl, F Ferrari, G Cioni, AF Bos: The qualitative assessment of general movements in preterm, term and young infants-review of the methodology. Early Hum Dev24 (1997) 47Suche in Google Scholar

15 Hopkins B, HFR Prechtl: A qualitative approach to the development of movements during early infancy. In: Prechtl HFR (Ed): Continuity of Neural Functions from Perinatal to Postnatal Life. Blackwell Scientific Publications, Oxford 1984, pp 179Suche in Google Scholar

16 Kurjak A, W Andonotopo, G Azumendi, N Vecek, B Funduk-Kurjak: Normal and abnormal fetal hand movements studied by 4D sonography. In: Kurjak A, JM Carrera (eds): Atlas of Clinical Application of Ultrasound in Obstetrics and Gynecology. Jaypee Brothers Medical Publishers, New Delhi 2005 (In Press)10.5005/jp/books/10226_16Suche in Google Scholar

17 Kurjak A, G Azumendi, N Vecek, S Kupesic, M Solak, D Varga: Fetal hand movements and facial expression in normal pregnancy studied by four-dimensional sonography. J Perinat Med31 (2003) 496Suche in Google Scholar

18 Kurjak A, JM Carrera, W Andonotopo, G Azumendi, M Medic, A Salihagic-Kadic: Behavioral perinatology assessed by four.dimensional sonography. In Kurjak A, FA Chervenak (eds): Textbook of Perinatal Medicine. Taylor & Francis, London 2005 (In Press)Suche in Google Scholar

19 Kurjak A, JM Carrera, W Andonotopo, M Stanojevic, E Scazzocchio, et al.: The role of 4D sonography in the neurological assessment of early human development. Ultrasound Rev Obstet Gynecol4 (2004) 148Suche in Google Scholar

20 Kurjak A, JM Carrera, A Salihagic Kadic, M Medic, W Andonotopo, et al.: The Antenatal development of fetal behavioural patterns assessed by four-dimensional sonography. J Matern Fetal Neonatal Med6 (2005) 401Suche in Google Scholar

21 Kurjak A, RK Pooh, JM Carrera, L Merce, A Salihagic-Kadic, W Andonotopo: Structural and functional early human development assessed by three-dimensional (3D) and four-dimensional (4D) sonography. Fertil Steril 2005 (In press)10.1016/j.fertnstert.2005.03.084Suche in Google Scholar

22 Kurjak A, M Stanojevic, W Andonotopo, A Salihagic-Kadic, G Azumendi, JM Carrera: Behavioral pattern continuity from prenatal to postnatal life – a study by four-dimensional (4D) ultrasonography. J Perinat Med32 (2004) 346Suche in Google Scholar

23 Kurjak A, M Stanojevic, W Andonotopo, E Scazzocchio-Duenas, G Azumendi, et al.: Fetal behaviour assessed in all three trimesters of normal pregnancy by four-dimensional (4D) ultrasonography. Croat Med J 2005 (In press)Suche in Google Scholar

24 Kurjak A, M Stanojevic, G Azumendi, JM Carrera. The potential of four-dimensional (4D) ultrasonography in the assessment of fetal awareness. J Perinat Med33 (2005) 46Suche in Google Scholar

25 Kurjak A, N Vecek, T Hafner, T Bozek, B Funduk-Kurjak, et al.: Prenatal diagnosis: what does four-dimensional ultrasound add? J Perinat Med30 (2002) 57Suche in Google Scholar

26 Kurjak A, N Vecek, S Kupesic, G Azumendi, M Solak: Four-dimensional ultrasound: how much does it improve perinatal practice? In: Carrera JM, FA Chervenak, A Kurjak (eds): Controversies in Perinatal Medicine, Studies on the Fetus as a Patient. Parthenon Publishing, New York 2003, pp 222Suche in Google Scholar

27 Nijhuis JG: Neurobehavioral Development of the fetal brain. In: Nijhuis JG (Ed): Fetal Behaviour: Developmental and Perinatal Aspects. Oxford University Press, Oxford 1992, pp 489Suche in Google Scholar

28 Pooh RK, T Ogura: Normal and abnormal fetal hand positioning and movement in early pregnancy detected by three- and four-dimensional ultrasound. Ultrasound Rev Obset Gynecol1 (2004) 46Suche in Google Scholar

29 Prechtl HFR, C Einspieler: Is neurological assessment ofthe fetus possible? Eur J Obstet Gynecol Reprod Biol75(1997) 8110.1016/S0301-2115(97)00197-8Suche in Google Scholar

30 Prechtl HFR: Qualitative changes of spontaneous movements in fetus and preterm infant are a marker of neurological dysfunction. Early Hum Dev23 (1990) 15110.1016/0378-3782(90)90011-7Suche in Google Scholar

31 Prechtl HFR: State of the art of a new functional assessment of the young nervous system. An early predictor of cerebral palsy. Early Hum Dev50 (1997) 110.1016/S0378-3782(97)00088-1Suche in Google Scholar

32 Prechtl HFR: Ultrasound studies of human fetal behaviour. Early Hum Dev12 (1985) 9110.1016/0378-3782(85)90173-2Suche in Google Scholar

33 Roodenburg PJ, JW Wladimiroff, A van Es, HFR Prechtl: Classification and quantitative aspects of fetal movements during the second half of normal pregnancy. Early Hum Dev25 (1991) 19Suche in Google Scholar

34 Stanojevic M, JM Perlman, W Andonotopo, A Kurjak: From fetal to neonatal behavioral status. Ultrasound Rev Obstet Gynecol4 (2004) 59Suche in Google Scholar

Published Online: 2006-01-11
Published in Print: 2006-02-01

©2006 by Walter de Gruyter Berlin New York

Heruntergeladen am 31.12.2025 von https://www.degruyterbrill.com/document/doi/10.1515/JPM.2006.007/html?lang=de
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