Comparison between HELLP syndrome, chronic hypertension, and superimposed preeclampsia on chronic hypertension without HELLP syndrome
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Mehmet A. Osmanağaoğlu
Abstract
Aim: To compare perinatal outcome of patients with HELLP syndrome to that of patients with chronic hypertension and superimposed preeclampsia on chronic hypertension without HELLP syndrome.
Methods: We retrospectively evaluated the perinatal outcome of 147 pregnancies complicated by the HELLP syndrome, chronic hypertension, and superimposed preeclampsia on chronic hypertension without HELLP syndrome.
Results: Gestational age at delivery and birthweights were lower among women with HELLP syndrome than among women with superimposed preeclampsia and chronic hypertension (P < 0.05). There were no statistically significant differences among the three groups with respect to intrauterine growth retardation, respiratory distress syndrome, intraventricular hemorrhage, necrotizing enterocolitis, Apgar score, admission to neonatal intensive care unit, overall rate of cesarean delivery and cesarean delivery rate for fetal distress. The total perinatal mortality rate was 17% (28/147) and was more frequent in the HELLP group (27%). Multivariate logistic regression analysis showed that gestational age at delivery (RR 0.45) and birthweight (RR 0.99) were risk factors for adverse outcome.
Conclusions: Perinatal outcome is primarily influenced by gestational age at delivery and birthweight independent of the severity of the hypertensive status of pregnant women.
References
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© Walter de Gruyter
Articles in the same Issue
- Author Index
- Subject Index
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- Difficult delivery of the impacted fetal head during cesarean section: intraoperative disengagement dystocia
- Breech presenting twin A: is vaginal delivery safe?
- Maternal serum interleukin-1β, -6 and -8 levels and potential determinants in pregnancy and peripartum
- Comparison between HELLP syndrome, chronic hypertension, and superimposed preeclampsia on chronic hypertension without HELLP syndrome
- Fetal scalp pH and ST analysis of the fetal ECG as an adjunct to CTG. A multi-center, observational study
- Effects of nitric oxide and prostacyclin on hemodynamic response by big endothelin-1 in near term fetal sheep
- Strategy for management of newborns with cervical teratoma
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- Detection of parvovirus B19, cytomegalovirus and enterovirus infections in cases of intrauterine fetal death
- Plasma endothelin-1 and clinical manifestations of neonatal sepsis
- Noncompaction of the left ventricular myocardium diagnosed in pregnant woman and neonate
- Ventricular bigeminy misdiagnosed as fetal bradycardia by cardiotocography – the value of non-invasive fetal electrocardiography
- Prolonged fetal bradycardia as the presenting clinical sign in Streptococcus agalactiae chorioamnionitis
- Changes of blood pressure and heart rate variability precede a grand mal seizure in a pregnant woman
- Myocardial infarction in early pregnancy
- The baby and the bathwater – a comment
- Reply to the opinion paper “The baby or the bathwater: which one should be discarded?”
Articles in the same Issue
- Author Index
- Subject Index
- Contents
- Difficult delivery of the impacted fetal head during cesarean section: intraoperative disengagement dystocia
- Breech presenting twin A: is vaginal delivery safe?
- Maternal serum interleukin-1β, -6 and -8 levels and potential determinants in pregnancy and peripartum
- Comparison between HELLP syndrome, chronic hypertension, and superimposed preeclampsia on chronic hypertension without HELLP syndrome
- Fetal scalp pH and ST analysis of the fetal ECG as an adjunct to CTG. A multi-center, observational study
- Effects of nitric oxide and prostacyclin on hemodynamic response by big endothelin-1 in near term fetal sheep
- Strategy for management of newborns with cervical teratoma
- Predicting neonatal outcomes: birthweight, body mass index or ponderal index?
- Markers of platelets activation, CD 62P and soluble P-selectin in healthy term neonates
- Detection of parvovirus B19, cytomegalovirus and enterovirus infections in cases of intrauterine fetal death
- Plasma endothelin-1 and clinical manifestations of neonatal sepsis
- Noncompaction of the left ventricular myocardium diagnosed in pregnant woman and neonate
- Ventricular bigeminy misdiagnosed as fetal bradycardia by cardiotocography – the value of non-invasive fetal electrocardiography
- Prolonged fetal bradycardia as the presenting clinical sign in Streptococcus agalactiae chorioamnionitis
- Changes of blood pressure and heart rate variability precede a grand mal seizure in a pregnant woman
- Myocardial infarction in early pregnancy
- The baby and the bathwater – a comment
- Reply to the opinion paper “The baby or the bathwater: which one should be discarded?”
