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Clinical characteristics and follow up of Down syndrome infants without congenital heart disease who presented with persistent pulmonary hypertension of newborn
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P. S. Shah
Published/Copyright:
June 1, 2005
Abstract
We identified seventeen infants with Down syndrome without structural congenital heart disease who presented with persistent pulmonary hypertension in the newborn period. Respiratory distress with or without hypoxia was the presenting feature in these infants. Pulmonary hypertension resolved in the majority of the survivors. Two infants with refractory pulmonary hypertension benefited from patent ductus arteriosus ligation. Autopsies in two infants demonstrated structural lung immaturity. We suggest that infants with Down syndrome are at risk of developing persistent pulmonary hypertension even in the absence of structural heart disease and these infants should be followed up until resolution of the pulmonary hypertension.
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Published Online: 2005-06-01
Published in Print: 2004-03-15
Copyright © 2004 by Walter de Gruyter GmbH & Co. KG
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- Fetal cardiovascular response to large placental chorioangiomas
- Characteristics of mothers who delivered the heaviest, average-weight, and lightest triplet sets
- Amniotic fluid concentrations of collagenase-1 and collagenase-3 are increased in polyhydramnios
- Oxytocic activity of thrombin: modulation of thrombin-induced gravid rat myometrial contractions by 5-hydroxytryptamine receptor antagonists
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- Ultrasonographic fetal weight estimation: accuracy of formulas and accuracy of examiners by birth weight from 500 to 5000 g
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- Clinical characteristics and follow up of Down syndrome infants without congenital heart disease who presented with persistent pulmonary hypertension of newborn
- Mortality and long term morbidity in esophageal atresia: the reduced impact of low birth weight and maturity on surgical outcome
- Non-hydropic intrauterine fetal death more than five months after primary parvovirus B19 infection
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