Cervical immunoglobulin A and altered vaginal flora in pregnant women with threatened preter delivery
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S. Glasow
Abstract
The aim of our study was to investigate the cervical immunoglobulin A concentration in women with threatened preterm delivery. Immunoglobulin A concentration in the cervical mucus of 80 women with symptoms of preterm delivery was measured using radial immunodiffusion. The results were compared with those of 60 healthy pregnant women. Concentrations of immunoglobulins in maternal serum were also measured. There was no significant difference of cervical immunoglobulin A (IgA) concentration between women with threatened preterm delivery and controls: 53.98 (0.0-189.7) mg/l vs. 61.7 (1.4-400.9; p<0.4) mg/l (median, range). The median of cervical IgA levels in the group of threatened preterm delivery did not differ significantly between patients delivered preterm (n=34) or at term (n=46): 38.3 (0.0-187.9) vs. 65.7 (1.4-189.7; p<0.2) mg/l. Women with a normal vaginal flora showed a significantly higher cervical IgA concentration than those with a pathological colonization: 72.7 (0.0-187.9) vs. 42.5 (0.0-189.7) mg/l. Patients with a pathological vaginal smear and preterm delivery had the lowest IgA levels (35.0; 0.0-187.9 mg/l). Measurement of cervical IgA concentration does not differentiate between women who deliver before or at term.
Copyright © 2004 by Walter de Gruyter GmbH & Co. KG
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- Congress Calendar
- Roster of Perinatal Societies
Articles in the same Issue
- Editorial
- The role of ultrasonography in recognizing the cause of fetal cerebral ventriculomegaly
- A kick from within – fetal movement counting and the cancelled progress in antenatal care
- DNA microarrays detect the expression of apoptosis-related genes in preeclamptic placentas
- Indicated labor induction with vaginal prostaglandin E2 increases the risk of cesarean section even in multiparous women with no previous cesarean section
- Cervical immunoglobulin A and altered vaginal flora in pregnant women with threatened preter delivery
- Multiple courses of antenatal corticosteroid therapy in patients with preterm premature rupture of membranes
- Implication of cord blood myeloperoxidase but of soluble p-selectin levels in preterm deliveries
- Fetal and early postnatal magnetic resonance imaging – is there a difference?
- Bone turnover markers and bone strength during the first weeks of life in very low birth weight premature infants
- The ponderal index in triplets: I. Relationship to small for gestational age neonates
- The ponderal index in triplets: II. Gestational age-related patterns of neonatal weights and lengths
- The ponderal index in triplets: III. Association with birth weight discordance
- The ponderal index in triplets: IV. Relationship with maternal height
- Intratracheal albumin reduces interleukin-8 in tracheobronchial aspirates in piglets after meconium aspiration
- The pulmonary paradox in premature infants: in-utero infected lungs do better than those with accelerated maturation
- Congenital syphilis: unique clinical presentation in three preterm newborns
- Twin-to-twin transfusion syndrome complicated by spontaneous mid-trimester uterine rupture
- Persistent pulmonary hypertension in a premature newborn after 16 hours of antenatal indomethacin exposure
- Congress Calendar
- Roster of Perinatal Societies
