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Cadmium concentration in maternal and cord blood and infant birth weight: a study on healthy non-smoking women

  • C. D. Salpietro , S. Gangemi , P. L. Minciullo , S. Briuglia , M. V. Merlino , A. Stelitano , M. Cristani , D. Trombetta and A. Saija
Published/Copyright: June 1, 2005
Journal of Perinatal Medicine
From the journal Volume 30 Issue 5

Abstract

The aim of our study was to measure, at delivery, maternal and cord blood cadmium levels (by means of atomic absorption spectrometry) in 45 healthy non-smoking pregnant women exposed to a low cadmium challenge, and to evaluate the relationship between these cadmium levels and the birth weight of the infants. Our results showed fairly low cadmium levels in maternal blood, in accordance with the fact that all women enrolled in this study lived in areas with low toxic metal contamination and that they did not smoke during their pregnancy. Furthermore, a highly significant direct correlation was found between maternal and cord blood cadmium concentrations. Since cadmium concentration appeared of the same order of magnitudine both in cord and maternal serum, one could speculate that cadmium is transferred easily from the mother to the fetus through the placenta. Finally, we found that birth weight is inversely correlated with maternal and cord blood cadmium concentrations; thus birth weight might be negatively influenced by cadmium levels as a result of the toxic effects of the metal on the placenta. Although preliminary, our data show that (also not-predictable) prenatal exposure to even low cadmium levels might be a risk factor for developmental impairment in infants.

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Published Online: 2005-06-01
Published in Print: 2002-09-26

Copyright © 2002 by Walter de Gruyter GmbH & Co. KG

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  6. Anal sphincter injury during vaginal delivery – an argument for cesarean section on request?
  7. Doppler sonography of uterine arteries at 20–23 weeks: risk assessment of adverse pregnancy outcome by quantification of impedance and notch
  8. Cadmium concentration in maternal and cord blood and infant birth weight: a study on healthy non-smoking women
  9. The effects of oral carbohydrate administration on fetal acid base balance
  10. Labor induction and meconium: in vitro effects of oxytocin, dinoprostone and misoprostol on rat ileum relative to myometrium
  11. Catch-up growth in fetal malnourished term infants
  12. Role of surfactant inhibitors in amniotic fluid in respiratory distress syndrome
  13. Congenital tuberculosis proven by percutaneous liver biopsy: report of a case
  14. A case of peripartum cardiomyopathy with a transient increase of plasma interleukin-6 concentration occurred following mirror syndrome
  15. Bilateral cystic adenomatoid lung malformation type III – a rare differential diagnosis of pulmonary hypertension in neonates
  16. An unexpected case of primary pulmonary hypertension of the neonate (PPHN). Potential role of topical administration of enoxolone
  17. Urethral catheterization in neonates – how far is too far?
  18. Congress Calendar
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