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Acute iliac vein thrombosis in pregnancy treated successfully by streptokinase lysis: a case report

  • Wolfgang Henrich , Annette Schmider , Martina Henrich and Joachim W. Dudenhausen
Published/Copyright: June 1, 2005
Journal of Perinatal Medicine
From the journal Volume 29 Issue 2

Abstract

Background: Postthrombotic syndrome is an important late complication after deep vein thrombosis in pregnancy. Thrombolytic agents are more efficient in preventing this condition but are rarely used in pregnant women.

Case: A 22-year-old woman at 29 weeks of gestation presented with acute iliac vein thrombosis. After application of a heparin bolus, systemic streptokinase lysis was performed. Low-dose heparin therapy was continued for the remainder of the, otherwise unremarkable, pregnancy. Spontaneous delivery of a healthy girl was without complications and thromboprophylaxis with low-molecular heparin was continued.

Conclusion: Thrombolysis in pregnancy is possible and may help to prevent severe long-term sequelae of thrombosis in young women. Bleeding is a major risk, which must be considered and therapy should only be administered under close observation.

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Published Online: 2005-06-01
Published in Print: 2001-04-05

Copyright © 2001 by Walter de Gruyter GmbH & Co. KG

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