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Incidence and birth weight characteristics of twins born to mothers aged 40 years or more compared with 35-39 years old mothers: a population study

  • Isaac Blickstein , Ran D. Goldman and Ram Mazkereth
Published/Copyright: June 1, 2005
Journal of Perinatal Medicine
From the journal Volume 29 Issue 2

Abstract

Objective: To compare the incidence of twin births and their birth weight characteristics in mothers aged ≥ 40 years with those of mothers aged 35–39 years.

Methods: We used a population-based cohort of Israeli twins delivered between 1993–98 to compare birth weight characteristics of 510 and 2102 twin pairs delivered to mothers aged ≥ 40 years (cases) and 35–39 years (controls), respectively.

Results: The incidence of twin mothers aged 40 years or more increased 50% during the study period, ten times more than mothers aged 35–39. There were significantly more nulliparas (P < .001, OR 1.54, 95% CI 1.2, 1.9) and more para ≥ 4 (P< .004, OR 1.38, 95% CI 1.1, 1.7) among older mothers. Irrespective of parity, there were no significant differences between mean twin birth weight, total twin birth weight < 3000 g, 3000–4999 g, and ≥ 5000 g, and frequencies of very low birth weight neonates.

Conclusions: Twin birth at the age of ≥ 40 years is significantly more likely among either nulliparas or para ≥ 4. Birth weight characteristics of twins delivered to mothers aged ≥ 40 years are not different from those delivered to 35–39 years old mothers.

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Published Online: 2005-06-01
Published in Print: 2001-04-05

Copyright © 2001 by Walter de Gruyter GmbH & Co. KG

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