Incidence and birth weight characteristics of twins born to mothers aged 40 years or more compared with 35-39 years old mothers: a population study
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Isaac Blickstein
, Ran D. Goldman and Ram Mazkereth
Abstract
Objective: To compare the incidence of twin births and their birth weight characteristics in mothers aged ≥ 40 years with those of mothers aged 35–39 years.
Methods: We used a population-based cohort of Israeli twins delivered between 1993–98 to compare birth weight characteristics of 510 and 2102 twin pairs delivered to mothers aged ≥ 40 years (cases) and 35–39 years (controls), respectively.
Results: The incidence of twin mothers aged 40 years or more increased 50% during the study period, ten times more than mothers aged 35–39. There were significantly more nulliparas (P < .001, OR 1.54, 95% CI 1.2, 1.9) and more para ≥ 4 (P< .004, OR 1.38, 95% CI 1.1, 1.7) among older mothers. Irrespective of parity, there were no significant differences between mean twin birth weight, total twin birth weight < 3000 g, 3000–4999 g, and ≥ 5000 g, and frequencies of very low birth weight neonates.
Conclusions: Twin birth at the age of ≥ 40 years is significantly more likely among either nulliparas or para ≥ 4. Birth weight characteristics of twins delivered to mothers aged ≥ 40 years are not different from those delivered to 35–39 years old mothers.
Copyright © 2001 by Walter de Gruyter GmbH & Co. KG
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Articles in the same Issue
- Malignant disease in pregnancy
- Repeated ultrasound guided fetal injections of corticosteroid alter nervous system maturation in the ovine fetus
- Incidence and birth weight characteristics of twins born to mothers aged 40 years or more compared with 35-39 years old mothers: a population study
- Lipopolysaccharide stimulation of 70 kilo Dalton heat shock protein messenger ribonucleic acid production in cultured human fetal membranes
- Effect of positive end expiratory pressure on functional residual capacity and compliance in surfactant-treated preterm infants
- Neonatal nucleated red blood cell counts in twins
- Normalisation of a severely abnormal ductus venosus Doppler flow velocity waveform in a growth-retarded fetus with absent end-diastolic flow in the umbilical artery and congenital anomalies
- Acute iliac vein thrombosis in pregnancy treated successfully by streptokinase lysis: a case report
- Liquid ventilation in an infant with persistent interstitial pulmonary emphysema
- Renal vein thrombosis in a newborn with prothrombotic genetic risk factors
- Fetal pulse oximetry allows safe continuation of labor in the presence of mild-moderate non reassuring CTG
- WAPM-Newsletter No 1