Artikel
Lizenziert
Nicht lizenziert Erfordert eine Authentifizierung

Psychiatric manifestations of latent toxoplasmosis. Potential mediation by indoleamine 2,3-dioxygenase

  • , , , , , , und
Veröffentlicht/Copyright: 1. November 2010
Veröffentlichen auch Sie bei De Gruyter Brill
Informationen für Autor*innen Erkunden Sie dieses Fachgebiet
International Journal on Disability and Human Development
Aus der Zeitschrift Band 9 Heft 1

Abstract

Toxoplasma gondii, a prevalent neurotropic parasite, induces immunological reactions that have the potential to affect brain and behavior. One possible connection between molecular mediators of inflammation (cytokines) and brain function and behavior is the activation of the enzyme indole-amine 2,3-dioxygenase, a mechanism implicated in containing T. gondii in the immunocompetent host, resulting in relative tryptophan depletion and kynurenine production. This could potentially lead to mood and behavioral dysregulation in latent toxoplasmosis.

Keywords: brain; depression; indoleamine 2,3-dioxygenase; schizophrenia toxoplasmosis
Corresponding author: Teodor T. Postolache, MD, Mood and Anxiety Program (MAP), Department of Psychiatry, University of Maryland School of Medicine, 685 West Baltimore Street, MSTF Building Room 930, Baltimore, MD 21201, USA
Received: 2009-11-16
Accepted: 2009-12-20
Published Online: 2010-11-01
Published in Print: 2010-11-01

©2010 by Walter de Gruyter Berlin New York

Artikel in diesem Heft

  1. Editorial
  2. New directions for disability and human development
  3. Review
  4. Psychiatric manifestations of latent toxoplasmosis. Potential mediation by indoleamine 2,3-dioxygenase
  5. Original Articles
  6. Associations between parent and child pain and functioning in a pediatric chronic pain sample: a mixed methods approach
  7. Health service utilization in patients with major depressive disorder experiencing significant somatic symptoms in Korea
  8. Movement skills in persons with Down syndrome decrease with aging
  9. Development of a community-specific health promotion plan to improve children's health in rural Guatemala
  10. No impact of gonadal steroid levels on the association between C-reactive protein and prepartum depression scores
  11. Pulmonary capillary wedge pressure estimation by Doppler echocardiography and cardiac catheterization: a study at a tertiary level hospital in Bangladesh
  12. National survey 2008 on medical services for persons with intellectual disability in residential care in Israel
  13. A longitudinal analysis of poverty among families supporting a child with a disability
  14. Case Reports
  15. Benign myelomalacia mimicking malignant spinal cord compression in a patient with metastatic non-small cell lung carcinoma: a case report
  16. A patient with the Fregoli syndrome: a case report and discussion of the relevant literature
https://doi.org/10.1515/IJDHD.2010.002
Schlagwörter für diesen Artikel
brain; depression; indoleamine 2,3-dioxygenase; schizophrenia toxoplasmosis

Artikel in diesem Heft

  1. Editorial
  2. New directions for disability and human development
  3. Review
  4. Psychiatric manifestations of latent toxoplasmosis. Potential mediation by indoleamine 2,3-dioxygenase
  5. Original Articles
  6. Associations between parent and child pain and functioning in a pediatric chronic pain sample: a mixed methods approach
  7. Health service utilization in patients with major depressive disorder experiencing significant somatic symptoms in Korea
  8. Movement skills in persons with Down syndrome decrease with aging
  9. Development of a community-specific health promotion plan to improve children's health in rural Guatemala
  10. No impact of gonadal steroid levels on the association between C-reactive protein and prepartum depression scores
  11. Pulmonary capillary wedge pressure estimation by Doppler echocardiography and cardiac catheterization: a study at a tertiary level hospital in Bangladesh
  12. National survey 2008 on medical services for persons with intellectual disability in residential care in Israel
  13. A longitudinal analysis of poverty among families supporting a child with a disability
  14. Case Reports
  15. Benign myelomalacia mimicking malignant spinal cord compression in a patient with metastatic non-small cell lung carcinoma: a case report
  16. A patient with the Fregoli syndrome: a case report and discussion of the relevant literature
Heruntergeladen am 10.4.2026 von https://www.degruyterbrill.com/document/doi/10.1515/IJDHD.2010.002/html
Button zum nach oben scrollen