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Intravenous immunoglobulin (IVIG): modes of action in the clinical management of recurrent pregnancy loss (RPL) and selected autoimmune disorders
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Charles O. A. Omwandho
Published/Copyright:
June 1, 2005
Abstract
Recurrent pregnancy loss has been associated with autoimmune responses to membrane phospholipids and alloimmune reactions against paternally derived molecules on the trophoblast. The problem is psychologically and economically stressful as it undermines the capacity of some couples to reproduce and participate effectively in the day-to-day economic activities. This article reviews the adoption of intravenous immunoglobulin as a form of therapy for the clinical management of recurrent pregnancy loss and of selected autoimmune disorders. Side effects, contraindications and safety of use are discussed.
Published Online: 2005-6-1
Published in Print: 2004-4-5
Copyright © 2004 by Walter de Gruyter GmbH & Co. KG
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Articles in the same Issue
- How useful are haematology analyser flags?
- Intravenous immunoglobulin (IVIG): modes of action in the clinical management of recurrent pregnancy loss (RPL) and selected autoimmune disorders
- Automated flagging influences the inconsistency and bias of band cell and atypical lymphocyte morphological differentials
- Extracellular concentration of homocysteine in human cell lines is influenced by specific inhibitors of cyst(e)ine transport
- Generation of eight adjacent mutations in a single step using a site-directed mutagenesis kit
- Prohepcidin accumulates in renal insufficiency
- Impurities from polypropylene microcentrifuge tubes as a potential source of interference in simultaneous analysis of multiple lipid-soluble antioxidants by HPLC with electrochemical detection
- Cerebrospinal fluid tau and Aβ42 concentrations in healthy subjects: delineation of reference intervals and their limitations
- The influence of smoking on plasma homocysteine and cysteine levels in passive and active smokers
- Reference change values and power functions
- A different approach to analyzing age-related HbA1c values in non-diabetic subjects
- Ratio of urinary free immunoglobulin light chain κ to λ in the diagnosis of Bence Jones proteinuria
- Influence of blood collection in plastic vs. glass evacuated serum-separator tubes on hormone and tumour marker levels
- Multicenter evaluation of a new immunoassay for procalcitonin measurement on the Kryptor® System
- Comparison of three commercial assays for the measurement of 17α-hydroxyprogesterone (17α-OHPR): limitations of the quality control system
- Analytical performance of the Albumin Cobalt Binding (ACB®) test on the Cobas MIRA® Plus analyzer
- Letter to the Editor
- Meetings and Awards
