Dry Chemistry Urinalysis of Pathological Proteinuria
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Dolphe Kutter
Abstract
The paper presents a review of the characteristics and analytical performance of the most current dry chemistry methods for detection and estimation of the different urinary proteins. Description of the classical “protein error” dipsticks for macroalbuminuria is supplemented by data on more sensitive alternatives based on the same principle, reaching into the zone of microalbuminuria. Immunological test strips are available for detection of low concentrations of albumin. Application of the same principle is attempted for detection of other specific proteins.
Highly sensitive enzymatic reactions allow detection of “lysis proteins”: haemoglobin, leukocyte esterase and β-N-acetyl-glucosaminidase.
An efficient strategy for screening for all types of pathological proteinuria based on detection of low albumin levels is presented.
Copyright © 1999 by Walter de Gruyter GmbH & Co. KG
Articles in the same Issue
- Author Index
- Contents
- Subject Index
- Polymorphisms of Coagulation Factor Genes a Review
- Urinalysis-Challenges by New Medical Needs and Advanced Technologies
- The Automation of Sediment Urinalysis Using a New Urine Flow Cytometer (UF-100™)
- Urinary Microscopy as Seen by Nephrologists
- Measurement of Urine Relative Density Using Refractometer and Reagent Strips
- Dry Chemistry Urinalysis of Pathological Proteinuria
- Physiopathology of Proteinuria and Laboratory Diagnostic Strategy Based on Single Protein Analysis
- Microalbuminuria in Diabetes
- European Multicentre Evaluation of the Super Aution SA-4220 Urinalysis Analyser
- Optimized Detection of DNA Point Mutations by Double Gradient Denaturing Gradient Gel
- Is the Association of Serum Lipase with β2-Microglobulin or C-Reactive Protein Useful for Establishing the Diagnosis and Prognosis of Patients with Acute Pancreatitis?
- Analytical and Clinical Performance of an Automated Immunoassay System (Immulite®) for Estradiol in Serum
- Evaluation of the Activated Partial Thrombo-plastin Time (APTT) Sensitivity to Heparin Using Five Commercial Reagents: Implications for Therapeutic Monitoring
- An Alternative Analysis for Crossover Studies that Accounts for Between-Group Disparities in Drug Response
Articles in the same Issue
- Author Index
- Contents
- Subject Index
- Polymorphisms of Coagulation Factor Genes a Review
- Urinalysis-Challenges by New Medical Needs and Advanced Technologies
- The Automation of Sediment Urinalysis Using a New Urine Flow Cytometer (UF-100™)
- Urinary Microscopy as Seen by Nephrologists
- Measurement of Urine Relative Density Using Refractometer and Reagent Strips
- Dry Chemistry Urinalysis of Pathological Proteinuria
- Physiopathology of Proteinuria and Laboratory Diagnostic Strategy Based on Single Protein Analysis
- Microalbuminuria in Diabetes
- European Multicentre Evaluation of the Super Aution SA-4220 Urinalysis Analyser
- Optimized Detection of DNA Point Mutations by Double Gradient Denaturing Gradient Gel
- Is the Association of Serum Lipase with β2-Microglobulin or C-Reactive Protein Useful for Establishing the Diagnosis and Prognosis of Patients with Acute Pancreatitis?
- Analytical and Clinical Performance of an Automated Immunoassay System (Immulite®) for Estradiol in Serum
- Evaluation of the Activated Partial Thrombo-plastin Time (APTT) Sensitivity to Heparin Using Five Commercial Reagents: Implications for Therapeutic Monitoring
- An Alternative Analysis for Crossover Studies that Accounts for Between-Group Disparities in Drug Response
