Management of Retinoblastoma

Chapters in this book

1. Frontmatter 1
2. Preface 5
3. Contents 7
4. Introduction
5. Modern Aspects of Malignant Growth 15
6. Section I. Tumors of the Uveal Tract
7. Chapter 1: Natural History of Uveal Melanomas
8. Changing Concepts Concerning the Natural History of Melanocytic Tumors of the Uvea 23
9. Small Melanomas: Diagnosis, Prognosis and Management 32
10. Very small Melanomas and Nevi of the Choroid. A Multifunctional Study 39
11. Melanomas: Ocular vs. Nonocular; Postmortem Metastatic Patterns 51
12. Congenital Melanosis Oculi and Its Relationship to Uveal Malignant Melanoma 58
13. Uveal Malignant Melanoma: Occurrence in Black Patients and Pregnancy 66
14. On Our Cases of Necrotic Choroidal Melanoma 75
15. Hormonal Influence on the Nevus of Ota 80
16. Malignant Melanomas of the Human Uvea in Denmark. Incidence and a 25-Year Follow-up of Cases Diagnosed Between 1943 and 1952 85
17. Organization of the Danish Centralized Centre for Patients with Malignant Choroidal Melanomas 93
18. Statistical Analysis of the Mortality from Malignant Neoplasms of the Eye in Japan and 17 Other Countries 100
19. Treatment of Malignant Choroidal Melanomas: Comparison of Survival after Conservative (¹⁰⁶Ru/¹⁰⁶Rh Applicator) Treatment and Enucleation, First Results of a GDR-wide Study, 1960—1980 109
20. Scanning Electron Microscopy of Epiretinal Choroidal Malignant Melanoma Cells 113
21. Prognostic Parameters in Malignant Melanoma of the Iris 120
22. Tumors of the Ciliary Body 129
23. Leiomyoma of the Ciliary Body, Clinical Aspects 138
24. Choroidal Osteoma 143
25. Streak Retinal Pigment Epitheliopathy. New Evidence in the Diagnosis of Choroidal Hemangioma 150
26. Chapter 2: Diagnostic Modalities
27. Diagnosis of Intraocular Tumors with Standardized Echography 154
28. Echographic Examinations on 110 Histologically Proven Intraocular Melanomas 176
29. Fluorescein-Angiography and the Differential Diagnosis of Intraocular Tumors 183
30. The Use of Fluorescein Angiography in the Differential Diagnosis of Secondary Retinal Detachment 191
31. Ophthalmochromoscopy in Choroidal and Optic Nerve Tumors 195
32. A Clinical Report on Infrared Photography for the Differential Diagnosis and Follow-up of Choroidal Tumors 199
33. The Value of Spectroscopy in the Diagnosis of Intraocular Tumors 203
34. The Spectral Analysis of Tumors. A new Diagnostic Concept 208
35. Non Contact Detection of Intraocular Tumors with Radionuclides ; Radiopharmaceuticals, Instrumentation and Clinical Aspects 219
36. Non-invasive Nuclear Detection of Choroidal Melanoma 227
37. More Precise Nuclear Studies for the Management of Small Choroidal Melanomas 235
38. The Reliability of Radioactive Phosphorus (³²P) in the Diagnosis of Intraocular Tumors; Experience with 912 Patients 239
39. The Significance of the ³²P test in Malignant Melanomas of the Eye 247
40. The Role of the ³²P Test in the Diagnosis of Ocular Tumors 251
41. Gamma-Isotope Scanning with ⁶⁷Gallium-. and ^99mTechnetium-Citrate in Choroidal Melanoma1 258
42. Chapter 3: Management of Uveal Melanomas (All Types of Therapy)
43. Modern Approaches to the Management of Intraocular Tumors 263
44. Photocoagulation of Choroidal Melanomas — Thirty Years Experience — 269
45. Treatment of Malignant Choroidal Melanomas by Xenon Photocoagulation 277
46. Conservative Treatment of Choroidal Melanoma by Cobalt 60 Applicators 286
47. Beta Irradiation with Ru-106/Rh-106 Applicators of Choroidal Melanomas: Sixteen Year's Experience 290
48. Ruthenium Irradiation of Choroidal Melanomas — Methods of Planning and Controlling Therapy 302
49. Retrogression of Choroidal Melanoma after Beta-Irradiation with Ruthenium-106/Rhodium-106 307
50. Tumor Regression and Functional Results in Sequential Ruthenium Therapy and Photocoagulation for Choroidal Melanoma 316
51. Ophthalmic Plaque Irradiation of Choroidal Melanoma 341
52. Proton Beam Irradiation of Uveal Melanomas: An Alternative of Enucleation 347
53. Helium Ion Therapy for Choroidal Melanoma 355
54. The Film as an Aid in the Documentation of the Management of Intraocular Tumors 364
55. Changing Attitudes Toward the Management of Posterior Uveal Melanomas 367
56. Results of Local Excision of Uveal Tumors 374
57. Indications, Technique and Results of the Surgical Treatment of Intraocular Melanomas 378
58. Blockexcision of Tumors of the Ciliary Body and Choroid 386
59. The Management of Uveal Neoplasm with Local Excision 396
60. Surgical Treatment of Tumors of the Anterior Uvea 404
61. Surgical Treatment of Melanomas of the Iris, Ciliary Body and Choroid 409
62. Conservative Treatment of Choroidal Melanomas Combined Use of Cobalt Plaques and Photocoagulation 417
63. Enucleation — When? 424
64. Cryotechnique for Freezing the Eye Before the So-called No-touch Enucleation 430
65. Chapter 4: Metastatic Tumors and Angiomatosis Retinae
66. Metastatic Tumors to the Uveal Tract 433
67. Ocular Involvement in Reticulum Cell Sarcoma ("Immunoblastic Sarcoma") 445
68. Angiomatosis Retinae Clinical, Epidemiological and Therapeutic Aspects 450
69. Section II. Retinoblastoma
70. The Histogenesis of Retinoblastoma 461
71. Diagnostic Techniques for Retinoblastoma 466
72. National Registration of Retinoblastoma in Japan 473
73. Genetic Counseling on Retinoblastoma 479
74. Transplantation of Retinoblastoma into the Nude Mouse and Radiation Effects 487
75. Management of Retinoblastoma 492
76. The New Essen Prognosis Classification for Conservative Sight Saving Treatment of Retinoblastoma 497
77. Therapeutic Techniques for Retinoblastoma 506
78. Immediate and Long term Results of Retinoblastoma Treatment in Children 514
79. Treatment of Retinoblastoma, Lausanne University Eye Hospital, 1944 to 1978 519
80. Treatment of Bilateral Retinoblastoma Results of Cases Treated at the Helsinki University Eye Hospital 1910—1980 525
81. Results Obtained in Treating Retinoblastoma Patients with Different Techniques at the Karolinska Hospital 529
82. Management of Retinoblastoma by Precision Megavoltage Irradiation 534
83. Chemotherapy in Retinoblastoma. Preliminary Report and Warning 541
84. Other Extraocular Neoplasms Associated with Retinoblastomas 543
85. Haptoglobin-Groups in Patients with Retinoblastoma 546
86. Lesions Clinically Simulating Retinoblastoma 550
87. Towards the Differential Diagnosis of the Retinoblastoma — the so-called Pseudoglioma 555
88. Section III. Immunology of Intraocular Tumors
89. A Contribution to the Immunology of Intraocular Melanoma 561
90. Retinoblastoma: Experimental Studies 569
91. Application of the Cell Electrophoretic Mobility Test and the Leucocyte Migration Inhibition Test in the Diagnosis of Malignant Intraocular Tumors 576
92. The Chances and Limits of Immunological Differentiation of Malignant Melanoma by the Macrophage Membrane Potential (MMP) Test 583
93. Immunologic Diagnosis of Uveal Melanoma 587
94. Carcinoembryonic Antigens in Retinoblastoma 592
95. Discussions 597
96. Contributors 618
97. Subject Index 622