Home Medicine Vitamin D. Basic Research and its Clinical Application
book: Vitamin D. Basic Research and its Clinical Application
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Vitamin D. Basic Research and its Clinical Application

Proceedings of the Fourth Workshop on Vitamin D, Berlin, West Germany, February 1979
  • Edited by: A. W. Norman , K. Schaefer , D. v. Herrath , H.-G. Grigoleit , J. W. Coburn , H. F. De Luca , E. B. Mawer and T. Suda
Language: English
Published/Copyright: 1979
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    Frontmatter

    I
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    Foreword

    V
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    Contents

    IX
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  • Chemistry, Structure, Function and Biological Assay
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    Introduction

    1
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    Synthesis of Some Side Chain Analogues of Vitamin D3 Metabolites

    13
    N. Ikekawa, M. Morisaki, N. Koizumi and Y. Hirano
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    Structural Transformations on Vitamin D

    21
    E. Zbiral and W. Reischl
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    Distribution and Activity of a Vitamin D3 Compound in Trisetum Flavescens

    33
    W. A. Rambeck, A. Wetzel, O. Kreutzberg and H. Zucker
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    Synthesis and Biological Activity of 24R-Hydroxy-25-fluorocholecalciferol and 1a, 24R-Dihydroxy-25-fluorocholecalciferol

    37
    J. J. Partridge, S.-J. Shiuey, A. Boris, J. P. Mallon and M. R. Uskokovic
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    The Synthesis and Biological Evaluation of Fluorinated Analoges as Probes of Vitamin Da Metabolism

    45
    J. L. Napoli, W. S. Mellon, M. A. Fivizzani, H. K. Schnoes and H. F. De Luca
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    19-Substituted-10,19-Dihydrovitamins via Hydrozirconation of Vitamin D3

    51
    A. W. Messing, F. P. Ross, M. Miura, A. W. Norman and W. H. Okamura
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    The Synthesis of 1a, 3a-Dihydroxy-25Methylcholesta-5,7-Diene-24-OIC Acid, and of la, 3a-Dihydroxy-25 Methylcholesta-5,7-Diene

    55
    J. M. Midgley, R. M. Upton, R. Watt and W. B. Whalley
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    Interconversion of Vitamin D and Trans-Vitamin D by Triplet-Sensitized Isomerization

    61
    H. J. C. Jacobs, J. W. J. Gielen and E. Havinga
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    The Use of UV, CD, 2H-NMR Spectroscopy and Mass Spectrometry for the Investigation of Conformational Mobility of Vitamin D and Previtamin D and their Interconversion

    65
    E. Berman, N. Friedman, Y. Mazur, M. Sheves and Zeev V. I. Zaretskii
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    25 (R), 26 and 25 (S), 26-(OH)2D3: Biological Activity in Intact and Nephrectomized Rats. Comparative Effects of 1, 25, 24 (R), 25-(OH)2D3 and I, 24 (R), 25-(OH)3D3

    73
    M. Thomasset, J. Redel, P. Marche and P. Cuisinier-Gleizes
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    Inhibitors of Vitamin D Metabolism and Action

    77
    B. L. Onisko, H. K. Schnoes and H. F. De Luca
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    C(1)-Hydroxylation of Vitamin D3 and Related Compounds

    81
    H. E. Paaren, H. K. Schnoes and H. F. De Luca
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    Vitamin D3 Sulfate in Lactating normally fed Rats and Suckling Pups After Maternal Administration of 3H Vitamin D3 or 35S Vitamin D3 Sulfate

    85
    N. Le Boulch, M. Laromiguiere, C. Marnay-Gulat, L. Miravet and Y. Raoul
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    Synthesis of Vitamin D Analogues and their Covalent Binding to Affinity Chromatographic Media

    89
    F. P. Ross, W. R. Wecksler, W. H. Okamura and A. W. Norman
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  • Osteoporosis
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    Calcium Absorption and Plasma 1,25 (OH)2D Levels in Post-Menopausal Osteoporosis

    99
    B. E. C. Nordin, M. Peacock, R. G. Crilly and D. H. Marshall
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    Osteoporosis and Age-Related Osteopenia: Evaluation of Possible Role of Vitamin D Endocrine System in Pathogenesis of Intestinal Calcium Absorption

    107
    B. L. Riggs, J. C. Gallagher and H. F. De Luca
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    Two Years Experience of Oral Treatment with 1a-Hydroxyvitamin D and Calcium in Patients with Senile or Postmenopausal Osteoporosis

    115
    T. S. Lindholm
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    The Treatment of Osteoporosis with 24,25 Dihydroxycholecalciferol A Pilot Study

    119
    J. Reeve, R. Hesp, P. Hulme, J. A. Kanis, L. Klenerman, P. Meunier, R. G. G. Russell, M. Tellez-Yudilevich, D. Williams and R. Wootton
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    Osteomalacic Factors in the Osteoporosis and the Treatment of Osteoporotic Patients with Vitamin D2 and 1aOHD3

    123
    K. Mizuno and J. Tanaka
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  • Transcalciferan/D-Binding Protein(s)
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    Biologic Significance of Genetic Variation in Human Gc (Vitamin D-Binding Protein)

    129
    S. P. Daiger
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    The Transport of Vitamin D

    137
    R. Bouillon and H. Van Baelen
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    Structure and Properties of Human Plasma Vitamin D Transport Protein (Group-Specific Component)

    149
    J. Svasti, A. Kurosky, A. Bennett, R. Surarit and B. H. Bowman
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    Serum Vitamin D Binding and Gc Polymorphism

    153
    J. Constans, M. Viau, J. P. Moatti and J. L. Clavere
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  • Sunlight, Skin and Seasonal Effects
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    Identification of in Vivo Generated Previtamin D3, Vitamin D3 and 25-Hydroxyvitamin D3 in the Vitamin D-Deficient Rats Irradiated by Ultraviolet Light

    159
    T. Kobayashi, T. Okano, K. Mizuno, N. Matsuyama, N. Nobuhara, K. Takada and T. Takao
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    Response of Plasma 250HD to Standardized Ultra Violet Radiation

    163
    M. Davie and D. E. M. Lawson
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    Effects of Sunlight Exposure on Blood Concentration of Vitamin D Derivatives in Healthy Japanese Adults

    165
    R. Morita, S. Dokoh, M. Fukunaga, I. Yamamoto and K. Torizuka
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    Contribution of Skin Vitamin D3 Synthesis in Patients Receiving Total Parenteral Nutrition

    169
    G. Jones, B. Byrnes, D. Duthie and K. N. Jeejeebhoy
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    The Photo-Biochemistry of Vitamin D3 in Vivo in the Skin

    173
    M. F. Holick, S. A. Holick, S. M. McNeill, N. Richtand, M. B. Clark and J. T. Potts
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  • Assays for Vitamin D Metabolites
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    Measurement of Plasma 1,25 (OH)2 Vitamin D by Protein Binding Assay and Radioimmunoassay

    179
    M. Peacock, G. A. Taylor and W. B. Brown
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    Use of Isotope Dilution Mass Fragmentography in Vitamin D Research

    183
    I. Björkhem, I. Holmbeg, T. Kristiansen, A. Larsson and J. I. Pedersen
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    Assay of 1,25-Dihydroxyvitamin D and Other Active Vitamin D Metabolites in Serum: Application to Animals and Humans

    189
    M. R. Haussler, M. K. Drezner, J. W. Pike, J. S. Chandler and L. A. Hagan
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    24,25-Dihydoxyvitamin D in Human Serum

    197
    C. M. Taylor
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    Radioimmunoassay of Vitamin D Metabolites

    205
    P. C. Schaefer and R. S. Goldsmith
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    Assays for Vitamin D and its Metabolites

    213
    R. L. Horst, R. M. Shepard, N. A. Jorgensen and H. F. De Luca
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    Radioimmunoassay for Circulating 1,25- and 25,26-Dihydroxycholecaliferols in Man

    221
    J. L. H. O’Riordan, T. L. Clemens, G. N. Hendy, L. J. Fraher, L. M. Sandler and S. E. Papapoulos
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    Hemisuccinates of Vitamin D3 and of its Metabolites

    229
    K. Lichtwald, E. Mayer, H. Schmidt-Gayk, J. Varga and S. Walch
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    Studies on Antisera against Vitamin D Metabolites

    233
    H. Schmidt-Gayk, E. Mayer, R. Schjier, K. Lichtwald, R. Bouillon and T. L. Clemens
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    The Measurement of Various Vitamin D Derivatives in Plasma Using High-Pressure Liquid Chromatography

    239
    S. Dokoh, R. Morita, M. Fukunaga, I. Yamamoto, A. Miyaji and K. Torizuka
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    Assay of 1,25- and 24,25 Dihydoxycholecalciferol in Human Serum - some Technical Considerations

    243
    R. S. Mason, D. Lissne, C. Reek and S. Posen
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    Radiocompetitive Protein Binding Assays for 25-Hydroxy Vitamin D, 24,25-Dihydroxyvitamin D and 1,25-Dihydroxy-vitamin D in Human Serum

    247
    S. Guillemant, R. Kremer, J. Eurin and J. Guillemant
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    Steroid Receptors: What do We not Know?

    251
    R. J. B. King
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  • Vitamin D - Parathyroid Hormone
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    Cholecalcifediol suppression of PTH Secretion from Monolayer Culture of Human Parathyroid Carcinoma Cells

    261
    M. Fukase, M. Tsutsumi, J. Iwasaki and T. Fujita
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    The Effect of Human Growth Hormone Replacement on Parathyroid Function and Vitamin D Metabolism

    265
    J. M. Gertner, R. L. Horst, M. Genel and H. Rasmussen
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    Serum Calcium Concentration: Possible Regulator of Renal Parathyroid Hormone Action

    267
    H. V. Lilienfeld-Toal, K. G. Mackes and E. Keck
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    Effects of Vitamin D3 Metabolites Injection into Thyro-parathyroidectomized Pregnant Rats on Fetal Weight and Liver Glycogen Stores in Mothers and Fetuses

    271
    J. M. Garel, M. Gilbert and P. Besnard
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    Effects of Vitamin Deficiency on Calcium-Binding Proteins and on Plasma Calcitonin and Parathyroid Hormone Levels in Growing Pigs

    275
    A. Pointiiiart, M. Thomasset and J. M. Garel
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    1,25 Dihydroxycholecalciferol effect on in Vitro Immunoreactive Human Parathyroid Hormone Secretion from Hyperplastic Glands

    279
    E. Mallet, J. P. Basuyau, M. C. Tonon and H. Vaudry
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    Quantitative Changes of Rat Thyroid C Cell Population in Hyper- and Hypovitaminosis D

    285
    M. Petko
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    The Interactions Between Vitamin D Metabolites, Parathyroid Hormone and Calcitonin

    289
    A. D. Care, D. W. Pickard, S. E. Papapoulos, J. L. H. O’Riordan, J. M. Garel and J. Redel
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    In Vivo Suppression of Parathyroid Hormone Secretion by 24,25 Dihydroxy Cholecalciferol in Hyperparathyroid Dogs

    297
    J. M. Canterbury, G. Gavellas, J. J. Bourgoignie and E. Reiss
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  • Renal Actions
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    Acute and Chronic Effects of Vitamin D Metabolites on the Renal Handling of Phosphate

    307
    J.-P. Bonjour, J. Caverzasio, H. Fleisch and U. Trechsel
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    Interaction of Vitamin D Metabolites with Parathyroid Hormone and Vasopressin

    315
    J. B. Puschett
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    Phosphaturie Effect of Parathyroid Hormone in Phosphate Depleted Man

    325
    J. C. Pena, J. Guerrero, S. Quiröz and J. Herrera
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  • Vitamin D in Maternal, Fetal and Neonatal Conditions
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    Long Term Effects of Low 25-Hydroxyvitamin D (25-OHD) Serum Concentrations in Premature infants: A Preliminary Report

    331
    L. S. Hillmann, D. V. Huebener and J. G. Haddad
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    Vitamin D, Calcium and Phosphorus Requirements and Bone Mineralization in Preterm Infants

    335
    J. J. Steichen, T. L. Gratton, L. Abrams-Becker and R. C. Tsang
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    The Transplacental Movement of Metabolites of Vitamin D in the Sheep

    341
    R. Ross, A. D. Care, C. M. Taylor, B. Pelc and B. A. Sommerville
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    The Effects of Solanum Glaucophyllum Ingestion by Pregnant Cows on Plasma Calcium Levels in Dams, Fetuses and Neonates and on the Mineral Composition of Colostrum

    345
    J. P. Barlet, R. Roux and M.-J. Davicco
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    The Vitamin D3 Requirement for Premature Infants

    349
    H. Wolf, V. Gräff and G. Offermann
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    Calcium Uptake and Binding by Membrane Fractions of Human Placenta: ATP Dependent Calcium Accumulation

    353
    J .A. Whitsett, M. Costello, D. Lo, J. Bohn and R. C. Tsang
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  • Skeletal Actions
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    Influence of 1,25(OH)2D3 on Bone Surface Lining Cells and on cartilage mineralisation in vitro. Ultrastructural studies

    359
    B. Krempien and F. Klimpel
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    The Role of Vitamin D Metabolites in Calcification of Chicken Epiphysis

    363
    A. Ornoy, E. Sekeles, R. Cohen and S. Edelstein
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    Bone Mineral Solubility and its Alteration by 1,25-Dihydroxyvitamin D3

    369
    R. Brommage and W. F. Neuman
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    Accelerated Bone Formation in End Stage Renal Disease

    373
    S. L. Teitelbaum, M. A. Bergfled, J. Freitag and K. A. Hruska
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    24,25-Dihydroxyvitamin D: The Preferred Metabolite for Bone

    381
    S. Edelstein and A. Ornoy
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    Cellular Location and Regulation of the 24,25-Dihydroxyvitamin D3 Formation in Cultured Cells from Bone and Cartilage

    391
    M. Carabedian, M. Lieberherr, M. T. Corvol, H. Guiollozo, C. L. Thil and S. Balsan
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    Comparison of the Histological Effect and Metabolism of 25-(OH)D and 1,25-(OH)2D in Rat Bone

    399
    J .A. Gallagher and D. E. M. Lawson
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    Action of Solanum Malacoxylon on Bone Histology of Vitamin D Deficient Rats

    403
    M. C. de Vernejoul, M. L. Queille, R. W. Nordin, C. A. Mautalen and L. Miravet
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    Dual Action of Parathyroid Hormone on the Mineralization of Rat Incisor Dentin

    411
    S. Matsumoto, T. Tsudzki and M. Yamaguchi
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    Influence of Diet on the Response of Bone Cells to 1,25-OH)2D3 in Thyroparathyroidectomized Rats

    415
    S. E. Weisbrode, C. C. Capen and A. W. Norman
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    Nuclear Binding of 24,25-(OH)2D3 and its Effect on DNA Polymerase Activities in Cultured Chondrocytes

    419
    M. T. Corvol, M. F. Dumontier, A. Ulmann, M. Garabedian and G. Witmer
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    Effects and Interaction of 1,25 (OH)2Ds and 24,25 (OH)2D3 on Bone

    425
    H. H. Malluche, H. Henry, W. A. Meyer, D. Sherman, S. G. Massry and A. W. Norman
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    Effects on Mineral Homeostasis of 1,25 (OH)2D3 and 24,25 (OH)2D3, Alone and in Combination, in Rats

    429
    B. S. Levine, D. B. N. Lee, N. Brautbar, M. W. Walling, C. R. Kleeman and J. W. Coburn
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    Effect of Dihydroxylated Vitamin D Metabolites on Experimental Rickets

    431
    D. Kraft, G. Offermann and R. Steldinger
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    Evidence for the Presence of 25-OH-D3 Binding Proteins in Embryonic Cartilage

    435
    F. Vittur, M. Zanetti, N. Stagni, R. Camerotto and B. de Bernard
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    Glucocorticoid Dependence of Cytosol 1,25-Dihydroxycholecalciferol Receptors in Fetal Rat Calvaria

    439
    S. C. Manolagas, D. C. Anderson and G. A. Lumb
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  • Vitamin D Metabolism
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    Recent Developments in the Metabolism of Vitamin D

    445
    H. F. De Luca and H. K. Schnoes
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    The Role of Systemic PH in the Bioactivation of Vitamin D

    459
    L. V. Avioli
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    The Site of Synthesis of 1,25(OH)2 Vitamin D3 in the Kidney A Microenzymatic Assay on Isolated Tubules

    463
    M. G. Brunette, M. Chan, C. Ferriere and K. D. Roberts
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    Response of Chick Kidney Cell Cultures to 1,25-Dihydroxyvitamin D3

    467
    H. E. Henry
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    Growth Hormone and Prolactin Action on Vitamin D Metabolism in the Rat

    475
    E. M. Spencer, O. Tobiassen, P. Ling and E. Braunstein
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    Effective Liver 25-Hydroxylation of Vitamin D under Chronic Ethanol Administration in the Rat

    479
    M. Gascon, B. Hollis and S. Mah
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    Calcium Transport by Rat Colon: Response to 1a,25(OH)2D3 and Dietary Calcium Restriction

    483
    M. J. Favus, S. C. Kathpalia and F. L. Coe
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    Direct Vitamin D3-Metabolite Regulation of Kidney 25-Hydroxyvitamin D3 Metabolism

    493
    J. L. Omdahl, L. A. Hunsaker and A. P. Evan
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    The Regulation of 25-Hydroxylation by Vitamin D Intake in Man: A Theoretical Model

    497
    A. M. Parfitt, M. Mathews, D. S. Rao and M. Kleerekoper
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    Minimal Deprivation of Vitamin D Enables Parathyroid Hormone to Stimulate 25-OH Vitamin D - 1a-Hydroxylase

    501
    B. E. Booth, H. C. Tsai and R. Curtis Morris
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    Vitamin D Metabolism in Japanese Quail: Effects of Lead Exposure and Dietary Calcium

    503
    S. N. Baksi and A. D. Kenny
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    Evidence for a Calcium-Dependent, PTH-lndependent Regulation of Plasma 1,25-Dihydroxyvitamin D in Rats

    511
    U. Trechsel, J. A. Eismann, J.-P. Bonjour and H. Fleisch
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    Computer Modeling of Vitamin Metabolism

    515
    J. L. Omdahl, R. C. Allen and R. P. Eaton
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    Prolactin, Growth Hormone and Vitamin D Metabolism

    523
    I. Maclntyre, D. J. Brown and E. Spanos
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    A Study of the Physiologic Significance of 24-Hydroxylation of 25-Hydroxyvitamin D

    531
    Y. Tanaka, H. F. DeLuca and N. Ikekawa
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    Dynamic Aspects of Vitamin D Metabolism: Formation of Hydroxylated Metabolites from A Physiological Dose of Cholecalciferol in Vitamin D Depleted Man

    537
    S. W. Stanbury
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    The Regulation of Plasma 1,25-(OH)2-D Concentrations in Healthy Adults

    545
    R. W. Gray, J. Lemann and N. D. Adams
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    The Role of the Liver in the Control of Vitamin D Metabolism

    553
    E. B. Mawer
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    Prostaglandins and 25-Hydroxyvitamin D-1a-Hydroxylase

    563
    J. D. Wark, R. G. Larkins, J. A. Eiman and T. J. Martin
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    Regulation of Plasma Levels of 1,25 Dihydroxy Vitamin D in Growing Dogs with Thyroparathroidectomy and Varying Amounts of Parathyroid Hormone

    567
    L. A. Nagode and C. L. Steinmeyer
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    Both 24R,25-Dihydroxyvitamin D3 and 1a,25-Dihydroxyvitamin D3 are Indispensable for Normal Calcium and Phosphorus Homeostasis

    571
    A. W. Norman and H. L. Henry
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    New Renal Metabolites of 24,25-Dihydroxyvitamin Ds in the Chick

    579
    T. Suda, Y. Takasaki and N. Horiuchi
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    The 1a- and 24-Hydroxylases of 25-Hydroxycholecalciferol: one or two Enzymes?

    587
    J. G. Ghazarian
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    Regulation of 25-Hydroxycholecalciferol-1 and -24-Hydroxylases in Cultured Kidney Cells

    597
    U. Trechsel, J. P. Bonjour and H. Fleisch
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    Possible Extra-Renal 25-OHD3-1a-Hydroxylase Activity in the Pregnant Rat

    605
    G. E. Lester, T. K. Gray and R. S. Lorenc
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    The Absorption and Metabolism of Vitamin D3 from Parenteral Injection Sites

    609
    M. Davies and E. B. Mawer
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    1,25-(OH)2 Vitamin D3 & 24,25-(OH)2 Vitamin D3 Synthesis by the Isolated Perfused Rat Kidney

    613
    A. M. Rosenthal, G. Jones, D. Fraser and S. W. Kooh
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    In Vitro Regulation of 25-Hydroxyvitamin D3 Metabolism by Avian Kidney Cells in Serum-Free Medium

    617
    R. Turner, G. A. Howard, J. I. Rader, B. L. Bottemiller and D. J. Baylink
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    Comparative Studies on Mitochondrial and Microsomal NADPH-Cytochromec Reductases of Chick Tissues

    621
    J .A. Kulkoski, J. L. Weber, J. E. Martinez and J. G. Ghazarian
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    Effect of Pregnancy, Acromegaly, Primary Hyperparathyroidism and Prolactinoma on 1,25-Dihydroxyvitamin D in Man

    625
    D. J. Brown, E. Spanos, P. Raptis and I. Maclntyre
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    Relationship of Dietary Phosphorus Restriction to Calcium Absorption and Vitamin D Metabolism

    629
    A. Bar and S. Hurwitz
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  • Intestinal Actions and Calcium Binding Protein: Meaning of Non-Parallel 1,25-Dihydroxycholecalciferol Mediated
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    Response Relationship in Intestine and Bone to Dose and Time

    639
    D. T. Zolock, R. L. Morrissey and D. D. Bikle
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    Cytoplasmic Localization of the Calcium Binding Protein in Rat Duodenal Absorptive Cells

    643
    P. Marche, C. Le Guern and P. Cassier
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    Visualization of Vitamin D-Dependent Calcium Binding Protein in Chick Intestine by Immuno-Scanning Electron Microscopy

    647
    S. Moriuchi, S. Yoshizawa, N. Hosoya, S. Noda and K. Kubota
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    Influence of High Doses of Vitamin D3 on Broilers and Adult Hens

    651
    P. Garcia Partida, C. Panizo, F. P. Montana and I. D. Prieto
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    Purification of the Intestinal Receptor for 1,25-Dihydroxyvitamin D

    659
    J. W. Pike and M. R. Haussler
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    Recent Progress on the Application of Affinity and Covalent Chromatography to the Purification of the 1,25-Dihydroxyvitamin D3 Receptor from Chick Intestinal Mucosa

    663
    W. R. Wecksler, F. P. Ross, W. H. Okamura and A. W. Norman
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    1,25-Dihydroxycholecalciferol and the Prevention of Parturient Hypocalcemia and Paresis ("Milk Fever") in Pregnant Dairy Cows

    667
    C. C. Capen, G. F. Hoffsis and A. W. Norman
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    A Vitamin D-Induced, Calcium-Binding Protein from Rat Intestinal Brush Border

    675
    A. Miller, T.-H. Ueng and F. Bronner
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    Relationship of Intestinal Calcium Absorption to Intestinal and Plasma Calcium Binding Protein Measured by a Radioimmunoassay

    679
    A. Bar and S. Hurwitz
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    The Effect of 1,25-Dihydroxycholecalciferol and Hydrocortisone on the Development of the Embryonic Chick Duodenum

    683
    N. Hosoya, S. Moriuchi, S. Yoshizawa, S. Noda and K. Kubota
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    Theories on the Mechanism of Action of 1,25(OH)3D3 on Active Intestinal Calcium and Inorganic Phosphate Absorption: are the Calcium and Phosphate Transport Processes Coupled, Uncoupled or Both?

    687
    M. W. Walling and D. B. N. Lee
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    Fundamental Actions of 1,25 Dihydroxycholecalciferol on Intestinal Ion Transport do not Involve Gene Activation

    693
    O. Fontaine, T. Matsumoto, M. Simoniescu, D. B. P. Goodman and H. Rasmussen
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    The Effect of Cholecalciferol on the Phosphorylation of Intestinal Membrane Proteins

    703
    R. H. Wasserman and M. E. Brindak
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    Some Biochemical Responses of Chick Intestine to 1,25- Dihydroxyvitamin D

    711
    D. E. M. Lawson, H. Harding, S. Lane and P. Wilson
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    Induction of Metallothionein(s) in Organ-Cultured Duodenum: Relationship to 1a,25-(OH)2D3-lnduced CaBP Synthesis

    731
    R. A. Corradino, C. S. Fullmer, E. Frelier and S. Maxwell
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    Vitamin D and Calcium Absorption: Computer Simulation

    735
    S. Hurwitz, H. Talpaz and A. Bar
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  • Renal Osteodystrophy
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    Clinical Assessments of Vitamin D3 - Therapy in Patients on Longterm Haemodialysis

    745
    W. Seeger, P. Müller, K. Buchali, I. Grossmann and C. Hansen
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    Adverse Effects of Vitamin D Metabolites on Osteitis Fibrosa in Patients on Chronic Hemodialysis: Critical Role of Induced Hyperphosphatemia

    751
    J. L. Sébert, J. F. de Frémont, J. Guéris, B. Coevoet, P. Marie, A. Smadja, D. Kuntz, A. Ryckewaert, P. Meunier and A. Fournier
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    Assessment of Long-Term Effects of 1a(OH)D3 on PTH Secretion, Intestinal Calcium Absorption and Bone in Chronic Renal Failure

    755
    S. Madsen, K. Ølgaard and J. Ladefoged
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    Hypergonadotropic Hypogonadism in Renal Failure - A Defect Responsive to 1,25(OH)2D3

    763
    W. Kreusser, U. Spiegelberg and E. Ritz
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    Comparative Effects of 1,25-Dihydroxycholecalciferol and Cholecalciferol in non-Dialyzed Chronic Renal Failure

    767
    M. S. Christensen, F. Meisen, C. Christiansen, B. Hartnack, O. Sjo and P. Rodbro
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    Medium term Effects of 1,25-Dihydroxy-vitamin D in Patients with Renal Osteopathy

    771
    E. Leicht, G. Biro, H. Baumhöfener and Chr. Blumy
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    The Early Detection and Treatment of Renal Osteodystrophy

    775
    P. E. Cordy
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    The Combined Use of Human Calcitonin and 1,25-Dihydroxycholecalciferol in the Treatment of Renal Osteodystrophy

    781
    K. Farrington, Z. Varghese and J. F. Moorhead
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    Intestinal Calcium Transport in Vitro as Influenced by Azotemia, Dietary Calcium, Parathyroidectomy and 1,25-Dihydroxycholecalciferol (1,25-DHCC) Treatment. - Role of Calcium - ATPase

    787
    H. Schiffl, N. Oswald and U. Binswanger
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    Recurrence of Hyperparathyroidism from Autografted Parathyroid Fragments in Uremic Patients in Spite of Administration of 25(OH)D3 and 1a(OH)D3

    791
    T. Drüeke, J. Zingraff, J. Guéris, N. Chkoff and C. Dubost
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    25 Hydroxycholecalciferol Plasma Levels in Anephric Patients After Oral Loading of Vitamin D

    795
    D. Brancaccio, G. Coen, C. Galmozzi, S. Casati and G. Lucentini
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    The Histological Study on Experimental Renal Osteodystrophy in Rats

    799
    R. Niki, H. Ohkawa, S. Suzuki, Y. Takagaki, M. Fukushima, M. Ono, T. Shimizu, Y. Nishii and T. Suda
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    Long Term Effects of Small Doses of 1,25 Dihydroxycholecalciferol in Dialysis Patients

    803
    B. Hochman, V. Gura, G. Boner, A. Weiss, A. J. Olah and J. Rosenfeld
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    Clinical and Biological Efficiency of 1,25 Dihydrocholecalciferol in Chronic Dialysis Patients with Renal Osteodystrophy

    807
    R. L. Schmitt, M. A. Dambacher, J. Gunçaga, A. G. Olah, A. Omichi and H. A. Jahn
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    Histomorphometric Evaluation of the effect of 1,25-DHCC in Type II and III of Renal Bone Disorders

    811
    G. Delling, H. Lühmann, M. Bulla, Ch. Fuchs, H. V. Henning, J. L. J. Jansen, R. Ziegler and W. Schulz
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    Histomorphometry of Bone Changes in Renal Osteodystrophy After Treatment with 1,25-Dihydroxycholecalciferol

    817
    A. J. Olah, H. Jahn, F. W. Reutter, R. König, A. Blumberg and A. Colombi
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    The use of 5,6-trans-25-OH-Cholecalciferol in the Treatment of Patients with Fully Developed Renal Osteopathy Requiring Dialysis: Therapeutical Application and Treatment Results

    821
    W. Cremer, N. Graben, H.-G. Grigoleit and P. Merguet
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    Clinical Experience in Long Term Treatment with 1,25-DHCC in Different Histological Forms of Renal Osteopathy

    827
    W. Schulz, P. Spiegel and G. Delling
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    Calcium-Phosphorus Metabolism and Renal Function During 1a-OH-D3 Vitamin Treatment of Patients with Chronic Renal Disease

    831
    H. E. Nielsen, M. S. Christensen, F. K. Romer, H. E. Hansen and F. Meisen
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    Newcastle Bone Disease

    835
    M. K. Ward, I. S. Parkinson, T. G. Feest, H. A. Ellis and D. N. S. Kerr
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    The Measurement of 1,25-(OH)2-D by Competitive Protein Binding Assay in the Plasma of Anephric Patients: The Effects of Dihydrotachysterol Therapy

    839
    R. W. Gray, N. D. Adams and J. Lemann
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    25-Hydroxycholecalciferol and 1,25 Dihydroxycholecalciferol in the Treatment of Renal Osteodystrophy

    843
    G. Coen, M. Taccone Gallucci, E. Bonucci and G. Bianchini
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    Bone Histomorphometry in Children with Early Chronic Renal Failure Treated with 25 (OH)D3

    847
    R. Baron, M. Norman, A. Mazur, A. Gruskin and H. Rasmussen
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    Hypercalcemia During Treatment of Uremic Patients with 1,25(OH)2D3: Analysis of 43 Cases

    851
    S. N. Winkler, A. S. Brickman, E. G. C. Wong, D. J. Sherrard, R. B. Miller, C. M. Bennet and J. W. Coburn
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    Renal Bone Disorder in Children: Therapy with Vitamin D3 or 1,25- Dihydroxycholecalciferol

    853
    M. Bulla, G. Delling, G. Offermann, R. Ziegler, G. Benz, H. Luehmann and A. Sanchez de Reutter
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    Treatment of Predialysis Renal Bone Disease with 1a-(OH) Vitamin D3 and 1.25-(OH)2 Vitamin D3. Initial Results of Balance Studies and the Effect on Intestinal Calcium Absorption, Serum PTH and Calcitonin Levels

    861
    J. R. Juttmann and J. C. Birkenhager
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    The Effect of 1-a-OHD3 on Bone Changes in Non-Dialysed Patients with Chronic Renal Insufficiency

    865
    F. Meisen, H. E. Nielsen and F. K. Romer
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    25 Hydroxyvitamin D in Renal Osteodystrophy: Long Term Results of A Six-Center Trial

    869
    R. R. Recker
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    Further Therapeutical Experience with the Vitamin D Analog 5,6-trans-25-OHCC in Renal Osteopathy

    877
    H.-G. Grigoleit, D. Kraft, K. Schaefer, G. Offermann, D. von Herrath and G. Delling
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    A New Laboratory Model for Renal Osteodystrophy and Vitamin D

    885
    Y. Nishii, M. Fukushima, T. Shimizu, M. Nanjo, R. Niki, H. Ohkawa, Y. Hinohara, M. Ogawa, Y. Tohira, H. Nakano, K. Okano and T. Suda
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    The Influence of Uremia, Aluminiumhydroxide and Various Vitamin D Compounds on the Course of Nutritional Rickets in Rats

    893
    D. von Herrath, K. Schaefer and B. Krempien
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    Effect of Vitamin D Analogs in Rats with Experimental Renal Osteodystrophy

    901
    K. Ueno, H. Kawashima, Y. Izawa, N. Ohnuma, T. Makita, S. Kurozumi, Y. Hashimoto, S. Ishimoto, Y. Kawaguchi, M. Yamamoto, Y. Kimura, Y. Ogura, Y. Ueda, K. Kushida and T. Inoue
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    Evaluation of Histological Procedures in the Investigation of Bone Disease Related to Vitamin D

    907
    E. Ritz, B. Krempien and H. H. Malluche
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  • Pathophysiology of Vitamin D Related Diseases
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    Effects of in Vitro and in Vivo Sodium Restriction on Corticosteroidinduced Intestinal Calcium Malabsorption

    915
    J. S. Adams and B. P. Lukert
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    Trisetum Calcinosis: Current Status of Clinical Research

    921
    G. Dirksen
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    X-Linked Hypophosphatemia is a Disorder of Phosphate Transport in the Renal Brush Border Membrane in the Hypophosphatemic Mouse. Why is Serum 1,25-(OH)2D Low in the Human Homologue?

    925
    H. S. Tenenhouse, C. R. Scriver and H. F. De Luca
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    The Effect of Vitamin D3 and Metabolites on Magnesium Metabolism

    933
    B. S. Levine, N. Brautbar, D. B. N. Lee, M. W. Walling, K. Kurokawa, C. R. Kleeman and J. W. Coburn
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    Subnormal Serum 1,25-Dihydroxyvitamin D3 Levels in Children with Glomerular Disease Receiving Corticosteroids

    935
    R. W. Chesney, R. B. Mazess, A. J. Hamstra, S. O’Regan and H. F. De Luca
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    Regulation of Serum Phosphorus by 1,25(OH)2D3

    939
    D. B. N. Lee, B. S. Levine, M. W. Walling, N. Brautbar, R. K. Lessman, V. Silis and J. W. Coburn
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    Unexplained hypercalcemia:? Sarcoidosis sine Sarcoidosis: with Elevated Serum Level of 1,25 DHCC

    941
    B. Frame and A. M. Parfitt
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    Vitamin D Metabolites in Hypercalcitoninemic States

    945
    R. Ziegler, F. Raue, M. Grossmann and H. Schmidt-Gayk
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    Target Cell Resistance in Pseudohypoparathyroidism: Single or Multiple?

    949
    A. M. Parfitt
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    Vitamin D Metabolism In Patients with Nephrolithiasis

    957
    J. Lemann, R. W. Gray and N. D. Adams
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    Evidence for Abnormal Metabolism of Vitamin D in Sarcoidosis

    963
    N. H. Bell
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    Effects of Experimental Diabetes in the Rat on Calcium Transport and Vitamin D Metabolism

    967
    H. P. Schedl
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    Absorption of Vitamin D and 25-OH Vitamin D in patients with Intestinal Malabsorption

    975
    E. L. Krawitt, E. B. Mawer and M. Davies
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    Effect of Diabetes in Rats on the Metabolism of Cholecalciferol and 25-Hydroxycholecalciferol

    979
    S. Sulimovici and M. A. Roginsky
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    Do Alkaline Phosphatases Have a Physiological Function?

    983
    S. Posen
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    Clinical Application of the 1,25-(OH)2D Assay

    991
    B. Lund, O. H. Sorensen and B. Lund
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    Elevated Plasma 1,25-(OH)2D Following Massive Dosing of Vitamin D3 in Dairy Cattle

    999
    R. L. Horst and E. T. Littledike
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    Vitamin D Metabolism in the Diabetic Rat

    1003
    R. L. Horst, S. L. Spoede and E. T. Littledike
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    The Effect of Chronic Excess or Deficiency of Growth Hormone on Plasma 1,25-Dihydroxyvitamin D Levels in man

    1005
    R. Kumar, T. J. Merimee, P. Silva and F. H. Epstein
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    25-Hydroxylation of Vitamin D in the Elderly

    1011
    R. K. Skinner
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    Intestinal Absorption of Radiophosphate After Physiological Doses of 1,25-Dihydroxyvitamin D in Normals and Pathological Conditions

    1015
    A. Caniggia and A. Vattimo
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    Calcium Metabolism Following Proximal Gastric Vagotomy in Man

    1019
    D. Scholz, P. O. Schwüle, W. Engelhardt and C. Morcinietz
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    25-Hydroxyvitamin D Metabolism in Nontropical Sprue

    1023
    S. B. Arnaud, A. D. Newcomer, K. P. Offord and V. L. W. Go
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    Circulating Vitamin D Metabolites in A Hypoparathyroid Patient Resistent to Vitamin D

    1027
    E. Keck and H. V. Lilienfeld-Toal
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    The Ability of 1a, 25-Dihydroxycholecalciferol to Alter the Fatty Acid Composition of Phosphoglycerides in Rat Intestinal Mucosa and Smooth Muscle

    1031
    W. Alastair, M. Hay, A. G. Hassam, M. A. Crawford, P. Stevens, E. B. Mawer and Ch. Case
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    Vitamin D Dependent Clinical Disorders - Bone Disease : Clinical Aspects - Unanswered Questions in Renal Osteodystrophy - Problems of Vitamin D Nomenclature - Addendum

    1035
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    Author Index

    1261
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    Subject Index

    1273
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    Backmatter

    1319
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Publishing information
Pages and Images/Illustrations in book
eBook published on:
October 26, 2020
eBook ISBN:
9783112330029
Hardcover published on:
December 31, 1979
Hardcover ISBN:
9783112330012
Edition:
Reprint 2020
Pages and Images/Illustrations in book
Front matter:
26
Main content:
1318
Other:
Num. figs.
https://doi.org/10.1515/9783112330029
eBook ISBN: 9783112330029
Hardcover ISBN: 9783112330012
Keywords for this book
Medizin; Vitamin
Audience(s) for this book
College/higher education;
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