14 Additive manufacturing and 4D printing applications for Industry 4.0-enabled digital biomedical and pharmaceutical sectors
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Sachin Sharma
Abstract
For the Industry 4.0-enabled digital biomedical and pharmaceutical sectors, additive manufacturing (AM) and four-dimensional (4D) printing have emerged as viable technologies. Layer-by-layer printing of 3D structures is what is known as AM, whereas 4D printing goes one step further by enabling the printed structures to change shape or functionality over time in response to outside stimuli. In the biomedical sector, AM and 4D printing offer the potential to revolutionize medical devices, prosthetics, and implants. In the pharmaceutical sector, AM and 4D printing offer the potential to revolutionize drug delivery systems. In this chapter, we study enabling technologies of drugdelivery systems that can release drugs at specific times and locations in response to physiological cues. This can improve drug efficacy and reduce side effects. However, the implementation of AM and 4D printing in the biomedical and pharmaceutical sectors also presents challenges related to regulatory approval, scalability, and safety. We also discuss AM and 4D printing in this chapter, which have enormous potential for the digital biomedical and pharmaceutical industries. These technologies have the potential to alter the way healthcare is delivered while also improving patient outcomes, lowering healthcare costs, and overcoming implementation-related obstacles.
Abstract
For the Industry 4.0-enabled digital biomedical and pharmaceutical sectors, additive manufacturing (AM) and four-dimensional (4D) printing have emerged as viable technologies. Layer-by-layer printing of 3D structures is what is known as AM, whereas 4D printing goes one step further by enabling the printed structures to change shape or functionality over time in response to outside stimuli. In the biomedical sector, AM and 4D printing offer the potential to revolutionize medical devices, prosthetics, and implants. In the pharmaceutical sector, AM and 4D printing offer the potential to revolutionize drug delivery systems. In this chapter, we study enabling technologies of drugdelivery systems that can release drugs at specific times and locations in response to physiological cues. This can improve drug efficacy and reduce side effects. However, the implementation of AM and 4D printing in the biomedical and pharmaceutical sectors also presents challenges related to regulatory approval, scalability, and safety. We also discuss AM and 4D printing in this chapter, which have enormous potential for the digital biomedical and pharmaceutical industries. These technologies have the potential to alter the way healthcare is delivered while also improving patient outcomes, lowering healthcare costs, and overcoming implementation-related obstacles.
Chapters in this book
- Frontmatter I
- Acknowledgments V
- Preface VII
- Contents XI
- List of contributors XV
- 1 3D-printed antennas 1
- 2 The recent developments in 3D bioprinting: a general bibliometric study and thematic investigation 39
- 3 Additive manufacturing of compositionally complex alloys: trends, challenges, and future perspectives 61
- 4 Adoptability of additive manufacturing process: design perceptive 77
- 5 Advanced bioprinting processes using additive manufacturing technologies: revolutionizing tissue engineering 95
- 6 Comparative analysis of thermal characteristics and optimizing laminar flow within medical-grade 3D printers for fabrication of sterile patientspecific implants (PSIs) using computational fluid dynamics 119
- 7 Review of 4D printing and materials enabling Industry 4.0 for implementation in manufacturing: an Indian context 143
- 8 Processing of smart materials by additive manufacturing and 4D printing 181
- 9 A comprehensive review on effect of DMLS process parameters and post-processing on quality of product in biomedical field 197
- 10 Finite element method investigation on delamination of 3D printed hybrid composites during the drilling operation 223
- 11 Analyzing the dimensional stability in direct ink written composite ink: a machine learning approach 235
- 12 Recent applications of rapid prototyping with 3D printing: a review 245
- 13 3D printing insight: techniques, application, and transformation 259
- 14 Additive manufacturing and 4D printing applications for Industry 4.0-enabled digital biomedical and pharmaceutical sectors 289
- 15 Application of three-dimensional printing in medical, agriculture, engineering, and other sectors 311
- 16 Recent developments in 3D printing: a critical analysis and deep dive into innovative real-world applications 335
- 17 Exploring design strategies for enhanced 3D printing performance 353
- Biographies 371
- Index 375
Chapters in this book
- Frontmatter I
- Acknowledgments V
- Preface VII
- Contents XI
- List of contributors XV
- 1 3D-printed antennas 1
- 2 The recent developments in 3D bioprinting: a general bibliometric study and thematic investigation 39
- 3 Additive manufacturing of compositionally complex alloys: trends, challenges, and future perspectives 61
- 4 Adoptability of additive manufacturing process: design perceptive 77
- 5 Advanced bioprinting processes using additive manufacturing technologies: revolutionizing tissue engineering 95
- 6 Comparative analysis of thermal characteristics and optimizing laminar flow within medical-grade 3D printers for fabrication of sterile patientspecific implants (PSIs) using computational fluid dynamics 119
- 7 Review of 4D printing and materials enabling Industry 4.0 for implementation in manufacturing: an Indian context 143
- 8 Processing of smart materials by additive manufacturing and 4D printing 181
- 9 A comprehensive review on effect of DMLS process parameters and post-processing on quality of product in biomedical field 197
- 10 Finite element method investigation on delamination of 3D printed hybrid composites during the drilling operation 223
- 11 Analyzing the dimensional stability in direct ink written composite ink: a machine learning approach 235
- 12 Recent applications of rapid prototyping with 3D printing: a review 245
- 13 3D printing insight: techniques, application, and transformation 259
- 14 Additive manufacturing and 4D printing applications for Industry 4.0-enabled digital biomedical and pharmaceutical sectors 289
- 15 Application of three-dimensional printing in medical, agriculture, engineering, and other sectors 311
- 16 Recent developments in 3D printing: a critical analysis and deep dive into innovative real-world applications 335
- 17 Exploring design strategies for enhanced 3D printing performance 353
- Biographies 371
- Index 375