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book: The Roots of Modern Biochemistry
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The Roots of Modern Biochemistry

Fritz Lippmann's Squiggle and its Consequences
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Language: English
Published/Copyright: 1988
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About this book

“The Roots of Modern Biochemistry is a superb introduction into modern biochemistry, much recommended as initial overview of the subject.”
Prof. Dr. Hans Fritz, Ludwig-Maximilians-University Munich

Topics

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    I-VI

    I
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    Preface

    VII
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    Contents

    IX
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  • 1. Fritz Lipmann (1899-1986)
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    1. Fritz Lipmann (1899-1986)

    1
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    Life with Fritz

    3
    Freda Hall Lipmann
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    A Long Life in Times of Great Upheaval

    9
    Fritz Lipmann
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    Fritz Lipmann: In Memoriam

    37
    Christian de Duve
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    Lipmann's Remarkably Fulfilled Life as a Researcher

    43
    Koscak Maruyama
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    Fritz Lipmann: June 12, 1899 - July 24, 1986

    63
    Hans G. Zachau
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    Fritz Lipmann Molding the Design of Molecular Bioenergetics

    67
    Herman Μ. Kalckar
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    Recollections of Fritz Lipmann, 1941-1945

    73
    H.A. Barker
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    In Celebration of the Scientific Genius of Fritz Lipmann

    81
    Sarah Ratner
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    Lipmann and "Not Strictly Biochemistry"

    85
    Thomas Peter Bennett
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    Communication in Metabolic Control Intuition and Method in Biochemistry: Four Years each with Krebs and Lipmann

    95
    Wieland Gevers
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    Fritz Lipmann: Squiggle to Protein Sulfation

    105
    Barbara Petrack
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    Fritz Lipmann (1899-1986), Honorary Member of the Leopoldina Academy

    109
    Β. Parthier
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    Dahlem in the Late Nineteen Twenties

    111
    Hans A. Krebs and Fritz Lipmann
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    Our Apprenticeship

    125
    Η. Blaschko
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    The Kaiser-Wilhelm-Institutes in Berlin-Dahlem in the Late 1930ies and Early 1940ies: Reminiscences of a Student of Biochemistry

    129
    Peter Karlson
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    On the Origin of the Squiggle (~)

    135
    Paul A. Srere
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  • 2. Biochemistry Comes of Age
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    2. Biochemistry Comes of Age

    139
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    The History of Metabolites Isolated from Urine

    141
    L.J. Moulton and H.A. Akers
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    The Pentose Phosphate Pathway

    147
    B.L. Horecker
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    Glycolysis and the Dawn of Modern Biochemistry

    157
    S.M. Rapoport
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    Energy-Rich Bonds and Enzymatic Peptide Synthesis

    165
    Joseph S. Fruton
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    A Nostalgic View of the TCA Cycle in Bacteria

    181
    Lester O. Krampitz
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    The Role of Vitamins and their Carrier Proteins in Citrate Fermentation

    191
    Peter Dimroth
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    Lipmann's Influence on Firefly Luminescence

    205
    W.D. McElroy
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    Sulfur in Biomimetic Peptide Syntheses

    213
    Th. Wieland
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    The Function of Teichoic Acids in Walls and Membranes of Bacteria

    223
    James Baddiley
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    The Amidotransferases: Origins of the Concept of Affinity Labeling of Enzymes

    231
    John M. Buchanan
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    Intracellular Protein Degradation: Past, Present and Future

    251
    S. Grisolia, E. Knecht and J. Hernández-Yago
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    Lipmann's Squiggle and the Unification of Cellular Structure and Function

    261
    Heinz Herrmann and Anne L. Hiskes
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    The Historical Intermingling of Biochemistry and Cell Biology

    285
    Philip Siekevitz
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    Regulation of Function of Membrane Proteins by Phosphorylation and Dephosphorylation

    295
    Efraim Racker
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    Molecular Biology of Brain Peptides and their Cognate Receptors

    305
    Dietmar Richter, Wolfgang Meyerhof, Steven D. Morley, Evita Mohr, Susanne Fehr and Hartwig Schmale
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    The Biological Activity of Tuftsin, Thr-Lys-Pro-Arg

    323
    V.A. Najjar
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    Biosynthesis of Linear Gramicidin, Pentadeca Peptide, is Tight Linked to Serine Metabolism and to Membranous Phosphoglyceride

    331
    Kou Kubota
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    From Phosphoenolpyruvate Carboxykinase to Sporulation: Personal Reflections on Dr. F. Lipmann

    339
    Kiyoshi Kurahashi, Toshihiko Ikeuchi and Jun Kudoh
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    Research on Nonribosomal Systems: Biosynthesis of Peptide Antibiotics

    355
    Hans von Döhren and Horst Kleinkauf
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    Metabolism of Carnosine and Related Peptides

    369
    Karl Bauer
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  • 3. Molecular Biology Sharpens its Tools
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    3. Molecular Biology Sharpens its Tools

    377
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    DNA Repair in Human Cells: Molecular Cloning of cDNAS Coding for Enzymes Related to Repair

    379
    Manfred Schweiger, Rainer Schneider, Monica Hirsch-Kauffmann, Bernhard Auer, Helmut Klocker, Elisabeth Scherzer, Martin Thurnher, Herbert Herzog, Hans-Peter Vosberg and Erwin F. Wagner
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    Acyl ~ Phosphate Intermediates in Oxidative DNA Sugar Damage by Antibiotics

    389
    Irving H. Goldberg
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    Rts1: A Multiphenotypic, Unusual Temperature Sensitive Drug Resistance Factor

    397
    A. Kaji, N. Okawa, M. Tanaka, K. Mori and S. Finver
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    The Partial Dependency of Human Prostatic Growth Factor on Steroid Hormones in Stimulating Thymidine Incorporation into DNA

    407
    Marion T. Hierowski, Michael W. McDonald, Lily Dunn and Jerry W. Sullivan
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    Developmentally Regulated Gene Amplification in Rhynchosciara

    417
    F.J.S. Lara
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    Fritz Lipmann, a Few Personal Memories, and: What Else Came Out of the High-Energy Phosphate Bond?

    423
    Wilfried F. Η. Μ. Mommaerts
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    Regulation of Gene Expression by Posttranslational Modification of Transcription Factors

    431
    Peter Herrlich and Michael Karin
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    How Does the Arginine Repressor Regulate the Synthesis of Arginine Biosynthetic Enzymes?

    441
    Werner K. Maas
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    The Biochemistry and Molecular Biology of the Terminal Reactions of Methionine Biosynthesis in Escherichia coli

    447
    Robert L. Shoeman, Mary E. Maxon, Timothy Coleman, Betty Redfield, Nathan Brot and Herbert Weissbach
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    The Wheat Embryo, Then and Now

    457
    B.G. Lane
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    Mechanism of Cytotoxic Action and Structures of Thiadiazolo-pyrimidines

    477
    M. Suiko
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    Architecture of Ribosomal Particles as Investigated by Image Reconstruction and X-Ray Crystallographic Studies

    481
    H.G. Wittmann and A. Yonath
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    Initiation of Protein Synthesis: Early Participation and Recent Revisit

    493
    Masayasu Nomura
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    Structure of Ribosomal RNA Genes of Eukaryotes: Some Solved and Unsolved Questions

    505
    A.A. Hadjiolov
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    Energetics and Dynamics of the Protein- Synthesizing Machinery

    511
    Alexander S. Spirin
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    Expression

    535
    J. Lawrence Fox
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    Punctuation in the Genetic Code: A Plausible Basis for the Degeneracy of the Code to Initiate Translation

    539
    M. Clelia Ganoza
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    Reconstruction of Translation: Role of EF-P in Regulation of Peptide Bond Formation

    551
    M. Clelia Ganoza, Ross M. Baxter and J. Lawrence Fox
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    On the Role of Spermine in Protein Synthesis

    555
    Željko Kućan
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  • 4. Functional Dynamics
  • 4.1 The Squiggle - Symbol of Bioenergetics
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    4.1 The Squiggle - Symbol of Bioenergetics

    565
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    Energy-Rich Compounds and Work

    569
    William P. Jencks
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    Squiggle Phosphate of Inorganic Pyrophosphate and Polyphosphates

    581
    Harland G. Wood
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    Enzymology of 3'-Squiggled Nucleotides

    603
    Jun-Ichiro Mukai
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    Pyridine Nucleotides as Group Transfering Coenzymes

    609
    H. Hilz
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    The Nature of Squiggle in Oxidative Phosphorylation

    625
    E.C. Slater
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    Motional Dynamics of Fatty Acids: Advantages of 15N and Deuterium Substituted Fatty Acid Spin Labels for Studies of Lipid-Protein Interactions and Motion in Membrane Bilayers

    631
    Jane Harting Park, Τ. K. Moore, B. Anderson and C. R. Park
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    Thyroid Hormones and Oxidative Phosphorylation

    645
    F. L. Hoch
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    Structure-Activity Relationships of Natural and Synthetic E-β-Methoxyacrylates of the Strobilurin and Oudemansin Series

    657
    T. Anke, G. Schramm, W. Steglich and G. von Jagow
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    The Intracellular Mechanism of Insulin Action

    663
    Samuel P. Bessman and Chandra Mohan
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    Unity and Diversity in Biological Redox Catalysis: Comparative Enzymology of Some Microbial Oxidoreductases Showing Variation in Cofactor Identity

    671
    J. A. Duine
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    Ammonia-Forming, Dissimilatory Nitrite Reductases as a Homologous Group of Hexaheme C-Type Cytochromes in Metabolically Diverse Bacteria

    683
    Ming-Cheh Liu and Harry D. Peck
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    Halorhodopsin

    693
    Janos Κ. Lanyi
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    Control of Futile Transmembrane Potassium Cycling in Escherichia coli

    699
    Evert P. Bakker
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    Bioenergetics of Protein Transport into Mitochondria: Role of ΔΨ and of Nucleoside Triphosphates

    707
    Nikolaus Pfanner and Walter Neupert
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    Some Recent Functional and Structural Contributions to the Molecular Mechanism of Photosynthesis

    713
    H. T. Witt
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    Salt Toxicity and Mineral Deficiency in Plants: Cytoplasmic Ion Homeostasis, a Necessity for Growth and Survival under Stress

    721
    Werner M. Kaiser, Georg Kaiser, Enrico Martinoia and Ulrich Heber
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  • 4.2 Molecular Recognition and Communication
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    4.2 Molecular Recognition and Communication

    735
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    Dawn of Ca Research: Regulation of Muscle Contraction

    737
    Setsuro Ebashi
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    Comparative Aspects of the Mechanisms of Energy Transduction in Sarcoplasmic Reticulum between Rabbit and Frog Skeletal Muscle

    747
    Yasuo Ogawa
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    Caltrin: A Versatile Regulator of Calcium Transport in Spermatozoa

    759
    Henry Lardy, Jovenal San Agustin and Carlos Coronel
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    Protein Kinase C, the Structural Heterogeneity and Differential Expression in Rat Brain

    765
    K. Ogita, U. Kikkawa, K. Ase, M.S. Shearman, Y. Nishizuka, Y. Ono, T. Fujii, T. Kurokawa, K. Igarashi, N. Saito and C. Tanaka
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    Regulation of Erythrocyte Membrane Cytoskeletal Protein Interactions by Phosphorylation

    771
    Mariano Tao
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    A Kinase Splitting Membranal Proteinase: Use in the Study of Receptors Involved in the Cellular Response to Hormones

    781
    S. Shaltiel, R. Seger and D. Goldblatt
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    Fritz Lipmann, Phosphoproteins and Regulation of Aromatic Amino Acid Hydroxylase Activity

    791
    Robert Roskoski
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    The Regulation of Hepatic Phenylalanine Hydroxylase by Phosphorylation- Dephosphorylation

    805
    S. Kaufman
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    Catabolite Inactivation and Adenylate Cyclase in Yeast

    813
    J. Sy, Y. Tamai and Y. Toyoda
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    Protein Modification by Tyrosine-Sulfation: Possible Functional Implications

    817
    Masahito Suiko and Ming-Cheh Liu
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    Proteoglycans and Connective Tissue Pathobiochemistry

    827
    A. Delbrück and E. Gurr
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    Acylation of Myelin Proteolipid Protein: A Link to the Past

    835
    Marjorie B. Lees
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    The Unusual Regulation of the Adenylyl cyclase of Amphibian Oocytes by Progesterone - A Review

    841
    Jorge E. Allende
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    Sterol Synergism, a Tool for Studies on Sterol Function

    853
    Konrad Bloch
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    Chemical Modification of Benzodiazepine Receptors of Cortical P2 Membranes

    857
    Le Fei, Zhang Zhao-geng and Zhou Ting-chung
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    Dual Pathways for the Catabolism of γ- Hydroxybutyrate: Cytosolic and Mitochondrial Mechanisms

    867
    Elaine E. Kaufmann
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  • 5. Evolution
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    5. Evolution

    879
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    Prebiotic Syntheses and the Mechanism of Early Chemical Evolution

    881
    Christian de Duve
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    Prebiotic Roots of Informed Protein Synthesis: Nature of the Lipmann Connection

    895
    Sidney W. Fox
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    A Case for an Additional RNA Base Pair in Early Evolution

    911
    Geoffrey Zubay
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    Inorganic Pyrophosphate in Cellular Energetics and Evolution

    917
    Herrick Baltscheffsky, Margareta Baltscheffsky, Maria Lundin and Pål Nyrén
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    Selforganization in Biosystems

    923
    A. Babloyantz
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    List of Contributors

    935
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    Acknowledgements

    943
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    Lipmann's Coworkers at Massachusetts General Hospital, Boston, and the Rockefeller University, New York

    945
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    Fritz Lipmann: Bibliography 1924-1985

    949
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    Index

    979
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Publishing information
Pages and Images/Illustrations in book
eBook published on:
July 13, 2011
eBook ISBN:
9783110852455
Hardcover published on:
April 1, 1988
Hardcover ISBN:
9783110115857
Edition:
Reprint 2011
Pages and Images/Illustrations in book
Front matter:
12
Main content:
994
Other:
Num. figs.
https://doi.org/10.1515/9783110852455
eBook ISBN: 9783110852455
Hardcover ISBN: 9783110115857
Keywords for this book
Biochemie; Kongress; Lipmann, Fritz Albert; Bibliographie 1924-1985
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