Contents

Chapters in this book

1. Frontmatter I
2. Contents V
3. Introduction 1
4. Chapter 1 Route, reagent and solvent selection 4
5. Chapter 2 Scale-up hazards 26
6. Chapter 3 Purification 43
7. Chapter 4 Polymorphs 62
8. Chapter 5 Optimisation and experimental design 74
9. Chapter 6 Automation 92
10. Chapter 7 Environmental and toxicology issues 103
11. Bibliography 119
12. Index 135