4 Chiral imidazolidinones: A class of priviliged organocatalysts in stereoselective organic synthesis
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Laura Raimondi
Abstract
Chiral molecules hold a mail position in Organic and Biological Chemistry, so pharmaceutical industry needs suitable strategies for drug synthesis. Moreover, Green Chemistry procedures are increasingly required in order to avoid environment deterioration. Catalytic synthesis, in particular organocatalysis, in thus a continuously expanding field. A survey of more recent researches involving chiral imidazolidinones is here presented, with a particular focus on immobilized catalytic systems.
Abstract
Chiral molecules hold a mail position in Organic and Biological Chemistry, so pharmaceutical industry needs suitable strategies for drug synthesis. Moreover, Green Chemistry procedures are increasingly required in order to avoid environment deterioration. Catalytic synthesis, in particular organocatalysis, in thus a continuously expanding field. A survey of more recent researches involving chiral imidazolidinones is here presented, with a particular focus on immobilized catalytic systems.
Chapters in this book
- Frontmatter I
- Preface V
- Contents VII
- Contributors List XIII
- 1 Domino and one-pot syntheses of biologically active compounds using diphenylprolinol silyl ether 1
- 2 Recent advances in reactions promoted by amino acids and oligopeptides 29
- 3 Amino-cinchona derivatives 85
- 4 Chiral imidazolidinones: A class of priviliged organocatalysts in stereoselective organic synthesis 177
- 5 Phase-transfer catalysis and the ion pair concept 197
- 6 Stereoselective organocascades: from fundamentals to recent developments 229
- 7 Basic principles of substrate activation through non-covalent bond interactions 263
- 8 Recent developments in stereoselective organocatalytic oxyfunctionalizations 293
- 9 Stereoselective synergystic organo photoredox catalysis with enamines and iminiums 331
- 10 Stereoselective organocatalysis and flow chemistry 365
- 11 Enantioselective organocatalytic approaches to active pharmaceutical ingredients – selected industrial examples 401
- Index 435
Chapters in this book
- Frontmatter I
- Preface V
- Contents VII
- Contributors List XIII
- 1 Domino and one-pot syntheses of biologically active compounds using diphenylprolinol silyl ether 1
- 2 Recent advances in reactions promoted by amino acids and oligopeptides 29
- 3 Amino-cinchona derivatives 85
- 4 Chiral imidazolidinones: A class of priviliged organocatalysts in stereoselective organic synthesis 177
- 5 Phase-transfer catalysis and the ion pair concept 197
- 6 Stereoselective organocascades: from fundamentals to recent developments 229
- 7 Basic principles of substrate activation through non-covalent bond interactions 263
- 8 Recent developments in stereoselective organocatalytic oxyfunctionalizations 293
- 9 Stereoselective synergystic organo photoredox catalysis with enamines and iminiums 331
- 10 Stereoselective organocatalysis and flow chemistry 365
- 11 Enantioselective organocatalytic approaches to active pharmaceutical ingredients – selected industrial examples 401
- Index 435
