Chapter
Publicly Available
2.3 Understanding the Metabolic Syndrome Using a Biomedical Chemistry Profile
-
Cidália Pereira
, Rosário Monteiro and Maria João Martins
Chapters in this book
- Frontmatter I
- Contents V
- Preface XI
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Section 1: Chemical Principles in Drug Design and Discovery
- 1.1 Functional Groups of Biomolecules and their Reactions 2
- 1.2 Designing Covalent Inhibitors: A Medicinal Chemistry Challenge 44
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Section 2: Chemical Basis of Drug Action and Diseases
- 2.1 Pharmacokinetics and Bioanalysis to Improve Drug Development 62
- 2.2 Translational Research in Endocrinology and Neuroimmunology Applied to Depression 119
- 2.3 Understanding the Metabolic Syndrome Using a Biomedical Chemistry Profile 132
- 2.4 Brain Neurochemistry and Cognitive Performance: Neurotransmitter Systems 148
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Section 3: Strategies to Develop New and Better Drugs
- 3.1 Amino Acids and Peptides in Medicine: Old or New Drugs? 178
- 3.2 Targeting Calcium-mediated Excitotoxicity in the CNS 229
- 3.3 Strategies for Conversion of Peptides to Peptidomimetic Drugs 245
- 3.4 Synthetic Vs. Natural Bioactive Compounds Against Tropical Disease 275
- 3.5 Current Trends and Developments for Nanotechnology in Cancer 290
- Index 343
Chapters in this book
- Frontmatter I
- Contents V
- Preface XI
-
Section 1: Chemical Principles in Drug Design and Discovery
- 1.1 Functional Groups of Biomolecules and their Reactions 2
- 1.2 Designing Covalent Inhibitors: A Medicinal Chemistry Challenge 44
-
Section 2: Chemical Basis of Drug Action and Diseases
- 2.1 Pharmacokinetics and Bioanalysis to Improve Drug Development 62
- 2.2 Translational Research in Endocrinology and Neuroimmunology Applied to Depression 119
- 2.3 Understanding the Metabolic Syndrome Using a Biomedical Chemistry Profile 132
- 2.4 Brain Neurochemistry and Cognitive Performance: Neurotransmitter Systems 148
-
Section 3: Strategies to Develop New and Better Drugs
- 3.1 Amino Acids and Peptides in Medicine: Old or New Drugs? 178
- 3.2 Targeting Calcium-mediated Excitotoxicity in the CNS 229
- 3.3 Strategies for Conversion of Peptides to Peptidomimetic Drugs 245
- 3.4 Synthetic Vs. Natural Bioactive Compounds Against Tropical Disease 275
- 3.5 Current Trends and Developments for Nanotechnology in Cancer 290
- Index 343