Progress towards the total synthesis of the enediyne anticancer antibiotics

Artikel in diesem Heft

1. Preface
2. Traditional Chinese medicines and new drug development
3. How Nature builds the pigments of life
4. Design, synthesis, and evaluation of DNA minor groove binding agents
5. Oxidative bond cleavage reactions in Nature; mechanistic and ecological aspects
6. From amino acids to prebiotic active peptides: A chemical reconstitution
7. Recent applications of radical reactions in natural product synthesis
8. Intramolecular strategies and stereoelectronic effects. Glycosides hydrolysis revisited
9. Hexose nucleic acids
10. Reflections on the total synthesis of natural products: Art, craft, logic, and the chiron approach
11. Evolution of catalytic function
12. DNA-drug interactions
13. Glycopeptides of biological interest: A challenge for chemical synthesis
14. Structural elucidation and chiral syntheses of insect pheromones and extension of the synthetic approaches
15. Possible evolutionary relationships in a signal transduction system
16. Biotin biosynthesis
17. Oncoprecipitins: A novel type of natural substances and oncofetal antigens
18. Comprehensive survey of endogenous regulators of crustacean moulting
19. Progress towards the total synthesis of the enediyne anticancer antibiotics
20. On the origins of organic matter in carbonaceous chondrites
21. The biosynthesis of triterpenoids of the hopane series in the Eubacteria: A mine of new enzymatic reactions
22. Genetically engineered synthesis of natural products
23. Biosynthesis and synthesis of bioactive natural lactams
24. Stereocontrolled synthesis via chiral aziridines
25. Superacidic cyclization of terpenoids
26. Oligonucleotide derivatives: Biologically active compounds targeted to specific genes
27. The cradle chemistry of life: On the origin of natural products in a pyrite-pulled chemoautotrophic origin of life
28. Synthesis of antitumour agents
29. Revised nomenclature for radicals, ions, radical ions and related species (IUPAC Recommendations 1993)