Article
Publicly Available
Targeting neurodegenerative diseases: Drug discovery in a challenging arena
-
Magid Abou-Gharbia
Published/Copyright:
June 7, 2012
Online erschienen: 2012-6-7
Erschienen im Druck: 2012-6-7
© 2013 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Preface
- Analogue-based drug discovery: Contributions to medicinal chemistry principles and drug design strategies. Microtubule stabilizers as a case in point (Special Topic Article)
- Targeting neurodegenerative diseases: Drug discovery in a challenging arena
- An acyl-Claisen approach to the synthesis of lignans and substituted pyrroles
- Spiroketals: Toward the synthesis of 39-oxobistramide K
- Designer chiral phase-transfer catalysts for green sustainable chemistry
- Influence of the difluoromethylene group (CF2) on the conformation and properties of selected organic compounds
- Stereoselective construction of 5,11-methanomorphanthridine and 5,10b-phenanthridine structural frameworks: Total syntheses of (±)-pancracine, (±)-brunsvigine, (±)-maritidine, and (±)-crinine
- New strategies for natural products containing chroman spiroketals
- Radical azidation reactions and their application in the synthesis of alkaloids
- Total synthesis of gelsemoxonine
- Chiral 2,6-bis(5',5'-diphenyloxazoline)pyridine as an efficient ligand for asymmetric catalysis
- Dynamic boronic acid-mediated autoligation of DNA strands
- Names and symbols of the elements with atomic numbers 114 and 116 (IUPAC Recommendations 2012)
Keywords for this article
Alzheimer’s;
BACE1;
bioactive molecules;
bioorganic chemistry;
computer-aided molecular design;
enzyme ILS-920;
immunophilin;
inhibitors;
macromolecular chemistry;
medicinal chemistry;
stroke;
WAY-258,131
Articles in the same Issue
- Preface
- Analogue-based drug discovery: Contributions to medicinal chemistry principles and drug design strategies. Microtubule stabilizers as a case in point (Special Topic Article)
- Targeting neurodegenerative diseases: Drug discovery in a challenging arena
- An acyl-Claisen approach to the synthesis of lignans and substituted pyrroles
- Spiroketals: Toward the synthesis of 39-oxobistramide K
- Designer chiral phase-transfer catalysts for green sustainable chemistry
- Influence of the difluoromethylene group (CF2) on the conformation and properties of selected organic compounds
- Stereoselective construction of 5,11-methanomorphanthridine and 5,10b-phenanthridine structural frameworks: Total syntheses of (±)-pancracine, (±)-brunsvigine, (±)-maritidine, and (±)-crinine
- New strategies for natural products containing chroman spiroketals
- Radical azidation reactions and their application in the synthesis of alkaloids
- Total synthesis of gelsemoxonine
- Chiral 2,6-bis(5',5'-diphenyloxazoline)pyridine as an efficient ligand for asymmetric catalysis
- Dynamic boronic acid-mediated autoligation of DNA strands
- Names and symbols of the elements with atomic numbers 114 and 116 (IUPAC Recommendations 2012)
