Chapters in this book

1. Frontmatter i
2. Contents vii
3. List of Illustrations ix
4. Preface xi
5. Acknowledgments xxi
6. List of Abbreviations xxv
7. 1. Hunting for the Elusive “Magic Bullet” 1
8. 2. A Hesitant Start: Patents, Politics, and Process 25
9. 3. Breakthroughs at the Bench 47
10. 4. The First Medical Applications 69
11. 5. Joy, Disappointment, Determination: Early Clinical Tests 88
12. 6. The Wild West of Antibody Commercialization 110
13. 7. The Challenge of Monoclonal Antibody Drugs 139
14. 8. Antibody Engineering: A Renaissance for Mab Therapeutics 159
15. 9. Blockbuster Mab Drugs 184
16. 10. A Quiet Revolution: The Legacy of Monoclonal Antibodies 218
17. Notes 237
18. Glossary 293
19. Bibliography 301
20. Index 307