Chapters in this book

1. Frontmatter ii
2. Contents vii
3. Acknowledgments ix
4. Abbreviations xi
5. One. Risk, Chance, and Causation 1
6. Two. Chance and Randomness 15
7. Three. Risk 35
8. Four. Randomization and Clinical Trials 51
9. Five. More Trials and Some Tribulations 70
10. Six. Harm 86
11. Seven. Screening, Diagnosis, and Prognosis 113
12. Eight. A Statistical Sojourn 127
13. Nine. Disease Clusters 144
14. Ten. Genetics and the Genome 154
15. Eleven. The Study of Mankind Is Man 171
16. Twelve. Celebrity Trumps Science 185
17. Thirteen. Replication and Pooling 200
18. Fourteen. Bias in Publication and Reporting 224
19. Fifteen. Causes 239
20. Sixteen. Ultimate Causation 260
21. Notes 277
22. Bibliography and Further Reading 303
23. Index 305