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Bringing light to the inner life of synapses

  • S.J. Sigrist

    Studied chemistry and biochemistry in Berlin and Tübingen. He received his PhD from the University of Tübingen in 1997. After postdoctoral training in neurogenetics he led a Max-Planck Junior Research Group at the European Neuroscience Institute (ENI) in Göttingen. Since 2008 he has been a full professor of neurogenetics at the Freie Universitaet Berlin, and a director of the Neurocure Cluster of Excellence. His work focuses on mechanisms of synapse assembly and plasticity, particularly the question of how functional and structural differentiation of synapses is integrated. To this end, high resolution light microscopy and intravital imaging are combined with genetic approaches in Drosophila melanogaster.

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    and C. Wichmann

    studied biology at the Georg-August University of Göttingen, Germany, from 1993 to 1999. After receiving her PhD in 2002, for which she investigated the activity of liposome-bound enzymes, she changed from microbiology to the field of neurosciences. She worked on the morphology of wild-type and mutant synapses of the fruitfly Drosophila via transmission electron microscopy as a member of Prof. Dr. Stephan Sigrist’s group at the European Neuroscience Institute Göttingen. She has been leading her own junior research group under Prof. Dr. Tobias Moser in the department of Otolaryngology at the UMG in Göttingen since July 2011. In this context, she is focusing on the molecular architecture and vesicle dynamics of mouse inner ear ribbon synapses, mainly using electron tomography and 3D serial reconstructions.

Published/Copyright: February 25, 2017
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Published Online: 2017-2-25
Published in Print: 2011-12-1

© 2017 by Walter de Gruyter Berlin/Boston

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