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Vestibular function is associated with immune inflammatory response

  • Zhaohui Song , Yuchuan Ding EMAIL logo , Nathan Sim , Ho Jun Yun , Jing Feng , Pan Gu and Xiaokun Geng EMAIL logo
Published/Copyright: January 1, 2024
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Abstract

Association between vestibular function and immune inflammatory response has garnered increasing interest. Immune responses can lead to anatomical or functional alterations of the vestibular system, and inflammatory reactions may impair hearing and balance. Vestibular disorders comprise a variety of conditions, such as vestibular neuritis, benign paroxysmal positional vertigo, Meniere’s disease, vestibular migraine, posterior circulation ischemia, and bilateral vestibular disease. Moreover, some patients with autoimmune diseases develop vestibulocochlear symptom. This paper offers an overview of prevalent vestibular diseases and discusses associations between vestibular dysfunction and immune diseases.


Corresponding authors: Yuchuan Ding, Department of Neurosurgery, Wayne State University School of Medicine, 550 E Canfield, 48201, Detroit, MI, USA, E-mail: ; and Xiaokun Geng, Department of Neurology and the Stroke Intervention and Translational Center (SITC), Beijing Luhe Hospital, Capital Medical University, No. 82 Xinhua South Road, 101149, Tongzhou District, Beijing, China; Department of Neurosurgery, Wayne State University School of Medicine, 550 E Canfield, 48201, Detroit, MI, USA; and China-America Institute of Neuroscience, Beijing Luhe Hospital, Capital Medical University, No. 82 Xinhua South Road, 101149, Tongzhou District, Beijing, China, E-mail:

  1. Research ethics: Not applicable.

  2. Author contributions: This paper was prepared by Zhaohui Song, supervised and revised by Yuchuan Ding, Jing Feng, Pan Gu, Xiaokun Geng, and objectively reviewed by Nathan Sim and Ho Jun Yun. All authors have contributed to the further revision of this article. The authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  3. Competing interests: The authors states no conflict of interest.

  4. Research funding: None declared.

  5. Data availability: Not applicable.

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Received: 2023-09-19
Accepted: 2023-11-10
Published Online: 2024-01-01
Published in Print: 2024-04-25

© 2023 Walter de Gruyter GmbH, Berlin/Boston

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