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Advanced titanium implants: combating corrosion and infection with cutting-edge coatings

  • Marijana R. Pantović Pavlović , Nenad L. Ignjatović ORCID logo , Senka Gudić , Ante Bilušić , Dragana Mladenović , Ladislav Vrsalović and Miroslav M. Pavlović ORCID logo EMAIL logo
Published/Copyright: December 17, 2024
Corrosion Reviews
From the journal Corrosion Reviews

Abstract

The presented research investigates the corrosion behavior of commercially pure titanium (cp-Ti) and amorphous calcium phosphate–chitosan (ACP@ChOL) coatings enriched with selenium on titanium in simulated body fluid (SBF). Using potentiodynamic polarization techniques, it was sought to derive essential corrosion parameters – corrosion potential, corrosion current density, breakdown potential, and passivation current. This study pioneers a comparative analysis of the corrosion stability of both samples. SEM/EDS analysis of surfaces pre- and postpotentiodynamic measurements offered insights into morphology and elemental composition. The aim was to elucidate the corrosion mechanism by integrating these techniques. Additionally, spontaneous corrosion behavior over 7 days, monitoring changes in open circuit potential, polarization resistance, and impedance were investigated. Furthermore, the antimicrobial efficacy of ACP@ChOL enriched with Se on titanium was assessed against Escherichia coli, Staphylococcus aureus, and Candida albicans, as well as in vitro release of Se. The presented study extends understanding, offering a unique perspective on the corrosion behavior and antimicrobial attributes of ACP@ChOL coatings enriched with Se on titanium. This composite material exhibits promise for medical applications, presenting an innovative avenue for addressing corrosion concerns and potentially reducing antibiotic reliance.


Corresponding author: Miroslav M. Pavlović, Department of Electrochemistry, Institute of Chemistry, Technology and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, Njegoševa 12, 11000 Belgrade, Serbia; and Center of Excellence in Chemistry and Environmental Engineering – ICTM, University of Belgrade, Njegoševa 12, 11000 Belgrade, Serbia, E-mail:

Funding source: Ministry of Science, Technological Development and Innovation of the Republic of Serbia

Award Identifier / Grant number: 451-03-66/2024-03/200026

Award Identifier / Grant number: 451-03-66/2024-03/200175

Award Identifier / Grant number: KK.01.1.1.02.0018

  1. Research ethics: Not applicable.

  2. Informed consent: The authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  3. Author contributions: Marijana R. Pantović Pavlović: conceptualization, methodology, validation, investigation, data curation, writing – original draft preparation, writing – review and editing, supervision. Nenad L. Ignjatović: conceptualization, methodology, formal analysis, resources, writing – review and editing, supervision, funding acquisition. Senka Gudić: investigation, methodology, writing – original draft preparation, writing – review and editing. Ante Bilušić: investigation, methodology, formal analysis. Dragana Mladenović: investigation, methodology, data curation. Ladislav Vrsalović: investigation, methodology, resources, writing – original draft preparation, writing – review and editing, funding acquisition. Miroslav M. Pavlović: methodology, validation, formal analysis, resources, data curation, writing – original draft preparation, writing – review and editing, visualization, supervision, funding acquisition.

  4. Use of Large Language Models, AI and Machine Learning Tools: No Large Language Models, AI and Machine Learning Tools have been used in preparation of the manuscript.

  5. Conflict of interest: The authors state no conflict of interest.

  6. Research funding: This work was supported by the Ministry of Science, Technological Development and Innovation of the Republic of Serbia (grant no. 451-03-66/2024-03/200026 and grant no. 451-03-66/2024-03/200175). The SEM/EDS analysis was made possible by the implementation of the project “Functional integration of the University of Split, PMF-ST, PFST AND KTFST through the development of scientific research infrastructure in the building of the three faculties” (KK.01.1.1.02.0018), funded by the European Commission through the European Regional Development Fund.

  7. Data availability: The raw data can be obtained on request from the corresponding author.

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Received: 2024-06-24
Accepted: 2024-10-21
Published Online: 2024-12-17

© 2024 Walter de Gruyter GmbH, Berlin/Boston

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