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5 Recent developments in the green synthesis of biologically relevant cinnolines and phthalazines

  • Ramadan Ahmed Mekheimer , Mohamed Abd-Elmonem , Mohamed Abou Elsebaa , Maiiada Hassan Nazmy and Kamal Usef Sadek
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Abstract

Both cinnolines and phthalazines are heterocyclic compounds which have a wide range of biological activities and pharmacological profiles. This work represents the recent advances in the green synthesis of cinnolines and phthalazines as 1,2 and 2,3-diazanaphalenes were cited. The docking studies and mode of action for key scaffolds were also reported.

Abstract

Both cinnolines and phthalazines are heterocyclic compounds which have a wide range of biological activities and pharmacological profiles. This work represents the recent advances in the green synthesis of cinnolines and phthalazines as 1,2 and 2,3-diazanaphalenes were cited. The docking studies and mode of action for key scaffolds were also reported.

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