Contents

Chapters in this book

1. Frontmatter i
2. About the Editors v
3. Historical Development and Perspectives of the Series vii
4. Preface to Volume 18 ix
5. Contents xiii
6. Contributors to Volume 18 xix
7. Titles of Volumes 1–44 in the Metal Ions in Biological Systems Series xxiii
8. Contents of Volumes in the Metal Ions in Life Sciences Series xxv
9. 1. CISPLATIN AND OXALIPLATIN: OUR CURRENT UNDERSTANDING OF THEIR ACTIONS 1
10. 2. POLYNUCLEAR PLATINUM COMPLEXES. STRUCTURAL DIVERSITY AND DNA BINDING 43
11. 3. PLATINUM(IV) PRODRUGS 69
12. 4. METALLOGLYCOMICS 109
13. 5. THE DECEPTIVELY SIMILAR RUTHENIUM(III) DRUG CANDIDATES KP1019 AND NAMI-A HAVE DIFFERENT ACTIONS. WHAT DID WE LEARN IN THE PAST 30 YEARS? 141
14. 6. MULTINUCLEAR ORGANOMETALLIC RUTHENIUM-ARENE COMPLEXES FOR CANCER THERAPY 171
15. 7. MEDICINAL CHEMISTRY OF GOLD ANTICANCER METALLODRUGS 199
16. 8. COORDINATION COMPLEXES OF TITANIUM(IV) FOR ANTICANCER THERAPY 219
17. 9. HEALTH BENEFITS OF VANADIUM AND ITS POTENTIAL AS AN ANTICANCER AGENT 251
18. 10. GALLIUM COMPLEXES AS ANTICANCER DRUGS 281
19. 11. NON-COVALENT METALLO-DRUGS: USING SHAPE TO TARGET DNA AND RNA JUNCTIONS AND OTHER NUCLEIC ACID STRUCTURES 303
20. 12. NUCLEIC ACID QUADRUPLEXES AND METALLO-DRUGS 325
21. 13. ANTITUMOR METALLODRUGS THAT TARGET PROTEINS 351
22. 14. METALLOINTERCALATORS AND METALLOINSERTORS: STRUCTURAL REQUIREMENTS FOR DNA RECOGNITION AND ANTICANCER ACTIVITY 387
23. 15. IRON AND ITS ROLE IN CANCER DEFENSE: A DOUBLE-EDGED SWORD 437
24. 16. COPPER COMPLEXES IN CANCER THERAPY 469
25. 17. TARGETING ZINC(II) SIGNALLING TO PREVENT CANCER 507
26. SUBJECT INDEX 531