Fostering Acceptance of Human Papillomavirus Vaccines
-
Anthony H. Dekker
Abstract
Multivalent prophylactic human papillomavirus (HPV) vaccines currently in the late stages of clinical testing are safe, immunogenic, and efficacious; and phase 3 tests of a quadrivalent vaccine show that it is 100% effective at preventing HPV types 16 and 18–associated cervical intraepithelial neoplasia grades 2 and 3, adenocarcinoma in situ, and cervical cancer through 2 years of postvaccination follow-up. These vaccines promise to reduce the burden of HPV-related disease. Realizing the full benefit of these vaccines will require a vaccination program that addresses the needs and concerns of healthcare providers, parents, and young adolescent patients who will be involved in the vaccine decision-making process. Osteopathic physicians, by virtue of their dedication to holistic care, are in an optimal position to play a key role in facilitating acceptance of these vaccines among potential vaccinees and their parents and guardians.
-
The comments within are not necessarily the position of the Indian Health Service or the US Public Health Service.
1 Gust DA, Woodruff R, Kennedy A, Brown C, Sheedy K, Hibbs B. Parental perceptions surrounding risks and benefits of immunization. Semin Pediatr Infect Dis. 2003;14:207 –212.10.1016/S1045-1870(03)00035-9Search in Google Scholar
2 Koutsky LA, Galloway DA, Holmes KK. Epidemiology of genital human papillomavirus infection. Epidemiol Rev. 1988;10:122 –163.10.1093/oxfordjournals.epirev.a036020Search in Google Scholar
3 Myers ER, McCrory DC, Nanda K, Bastian L, Matchar DB. Mathematical model for the natural history of human papillomavirus infection and cervical carcinogenesis. Am J Epidemiol. 2000;151:1158 –1171.10.1093/oxfordjournals.aje.a010166Search in Google Scholar
4 Newacheck PW, Park MJ, Brindis CD, Biehl M, Irwin CE Jr. Trends in private and public health insurance for adolescents. JAMA. 2004;291:1231 –1237.10.1001/jama.291.10.1231Search in Google Scholar
5 Burstein GR, Lowry R, Klein JD, Santelli JS. Missed opportunities for sexually transmitted diseases, human immunodeficiency virus, and pregnancy prevention services during adolescent health supervision visits. Pediatrics. 2003;111:996 –1001.10.1542/peds.111.5.996Search in Google Scholar
6 Yacobi E, Tennant C, Ferrante J, Pal N, Roetzheim R. University students' knowledge and awareness of HPV. Prev Med. 1999;28:535 –541.10.1006/pmed.1999.0486Search in Google Scholar
7 Lambert EC. College students' knowledge of human papillomavirus and effectiveness of a brief educational intervention. J Am Board Fam Pract. 2001;14:178 –183.Search in Google Scholar
8 Mays RM, Zimet GD, Winston Y, Kee R, Dickes J, Su L. Human papillomavirus, genital warts, Pap smears, and cervical cancer: knowledge and beliefs of adolescent and adult women. Health Care Women Int. 2000;21:361 –374.10.1080/07399330050082218Search in Google Scholar
9 Boehner CW, Howe SR, Bernstein DI, Rosenthal SL. Viral sexually transmitted disease vaccine acceptability among college students. Sex Transm Dis. 2003;30:774 –778.10.1097/01.OLQ.0000078823.05041.9ESearch in Google Scholar
10 Kahn JA, Rosenthal SL, Hamann T, Bernstein DI. Attitudes about human papillomavirus vaccine in young women. Int J STD AIDS. 2003;14:300 –306.10.1258/095646203321605486Search in Google Scholar
11 Mays RM, Sturm LA, Zimet GD. Parental perspectives on vaccinating children against sexually transmitted infections. Soc Sci Med. 2004;58:1405 –1413.10.1016/S0277-9536(03)00335-6Search in Google Scholar
12 Olshen E, Woods ER, Austin SB, Luskin M, Bauchner H. Parental acceptance of the human papillomavirus vaccine. J Adolesc Health. 2005;37:248 –251.10.1016/j.jadohealth.2005.05.016Search in Google Scholar PubMed
13 Prochaska JO, DiClemente CC, Norcross JC. In search of how people change. Applications to addictive behaviors. Am Psychol. 1992;47:1102 –1114.10.1037/0003-066X.47.9.1102Search in Google Scholar
14 Zimet GD, Mays RM, Winston Y, Kee R, Dickes J, Su L. Acceptability of human papillomavirus immunization. J Womens Health Gend Based Med. 2000;9:47 –50.10.1089/152460900318957Search in Google Scholar PubMed
15 Hoover DR, Carfioli B, Moench EA. Attitudes of adolescent/young adult women toward human papillomavirus vaccination and clinical trials. Health Care Women Int. 2000;21:375 –391.10.1080/07399330050082227Search in Google Scholar PubMed
16 Raley JC, Followwill KA, Zimet GD, Ault KA. Gynecologists' attitudes regarding human papilloma virus vaccination: a survey of Fellows of the American College of Obstetricians and Gynecologists. Infect Dis Obstet Gynecol. 2004;12:127 –133.10.1080/10647440400020661Search in Google Scholar PubMed PubMed Central
17 Mays RM, Zimet GD. Recommending STI vaccination to parents of adolescents: the attitudes of nurse practitioners. Sex Transm Dis. 2004;31:428 –432.10.1097/01.OLQ.0000130536.71812.E5Search in Google Scholar
18 HPV Vaccines: Are We Closer to Preventing Cervical Cancer and Other HPV-Related Diseases? American College of Osteopathic Family Physicians Symposium at American Osteopathic Association Unified Convention in Orlando, Fla, 1026,2005 .Search in Google Scholar
The American Osteopathic Association
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles in the same Issue
- EDITOR'S MESSAGE
- Infections With Human Papillomavirus: Hope for Prevention and Guidance for Diagnosis and Management
- INTRODUCTORY MESSAGE
- HPV Vaccines: Are We Closer to Preventing Cervical Cancer and Other HPV-Related Diseases?
- ARTICLES
- 10.7556/jaoa.2006.20002
- 10.7556/jaoa.2006.20003
- 10.7556/jaoa.2006.20004
- Quizzes in AOA Publications Now Have 18-Month Life Span
Articles in the same Issue
- EDITOR'S MESSAGE
- Infections With Human Papillomavirus: Hope for Prevention and Guidance for Diagnosis and Management
- INTRODUCTORY MESSAGE
- HPV Vaccines: Are We Closer to Preventing Cervical Cancer and Other HPV-Related Diseases?
- ARTICLES
- 10.7556/jaoa.2006.20002
- 10.7556/jaoa.2006.20003
- 10.7556/jaoa.2006.20004
- Quizzes in AOA Publications Now Have 18-Month Life Span