Chapter
Licensed
Unlicensed
Requires Authentication
Proteins and Polypeptides
-
Emil Fischer
You are currently not able to access this content.
You are currently not able to access this content.
Chapters in this book
- Frontmatter i
- General Editor’s Preface v
- Preface vii
- Contents xi
- Introduction 1
-
Part I. Techniques
-
ANALYTICAL METHODS
-
Microanalysis
- On Microchemistry, with Special Attention to the Work of H. Behrens 3
- Quantitative Organic Microanalysis 6
-
PHYSIOCHEMICAL ANALYSIS
- The Inner Friction of Binary Mixtures. Characteristics of Definite Compounds 8
-
POLAROGRAPHY
- The Processes at the Mercury Dropping Cathode. Part I. The Deposition of Metals 10
-
Hydrogen Ion Concentration; pH
- Enzyme Studies II. The Measurement and Meaning of Hydrogen Ion Concentration in Enzymatic Processes 16
-
OPTICAL METHODS
-
The Ultramicroscope
- On Making Visible and Determining the Size of Ultramicroscopic2 Particles with Special Attention to Gold Ruby Glasses 19
-
METHODS OF SEPARATION
-
CHROMATOGRAPHY
- Physical Chemical Studies on Chlorophyll. Adsorptions 22
- Qualitative Analysis of Proteins: A Partition Chromatographic Method Using Paper 28
- The Separation of Rare Earths by Ion Exchange. I. Cerium and Yttrium 30
-
SEPARATIONS OF PROTEINS BY SEDIMENTATION AND ELECTROPHORESIS
- Determination of the Size and Distribution of Size of Particles by Centrifugal Methods 31
- Sedimentation of Molecules in Centrifugal Fields 35
- A New Apparatus for Electrophoretic Analysis of Colloidal Mixtures 42
-
RADIOACTIVE TRACERS
- The Absorption and Translocation of Lead by Plants. A Contribution to the Application of the Method of Radioactive Indicators in the Investigation of the Change of Substance in Plants 48
- Radioactive Indicators in the Study of Phosphorus Metabolism in Rats 50
-
CRYSTAL STRUCTURE
- Interference Phenomena in Roentgen Rays 53
- The Reflection of X-Rays by Crystals 54
-
Part II. General and Physical Chemistry
-
ATOMIC AND MOLECULAR STRUCTURE
-
RADIOACTIVE DECAY SERIES
- Radioactive Transformations and the Periodic System of the Elements 67
- The Radio-Elements and the Periodic Law 75
-
ISOTOPES
- The Atomic Weight of Lead of Radioactive Origin 78
- The Atomic Weight of Lead from Pitchblende 82
- The Constitution of Atmospheric Neon 84
- A Hydrogen Isotope of Mass 2 91
-
MOLECULAR STRUCTURE
- Molecule Formation as a Question of Atomic Structure 93
- The Atom and the Molecule 100
- The Arrangement of Electrons in Atoms and Molecules 107
- Polarity and Ionization from the Standpoint of the Lewis Theory of Valence 110
- Co-ordination Compounds 112
-
DIPOLE MOMENTS
- Some Results of a Kinetic Theory of Insulators (Preliminary Communication) 116
-
SPREADING OF FILMS ON LIQUIDS
- The Constitution and Fundamental Properties of Solids and Liquids. II Liquids 123
-
APPLICATION OF QUANTUM MECHANICS
- Significance of Tautomerism and of the Reactions of Aromatic Compounds in the Electronic Theory of Organic Reactions 131
- The New Quantum Mechanics 141
- Wave Mechanics and the Normal State of the Hydrogen Molecule 151
- The Nature of the Chemical Bond. V The Quantum Mechanical Calculation of the Resonance Energy of Benzene and Naphthalene and the Hydrocarbon Free Radicals 156
-
PHYSICAL CHEMISTRY
-
COLLOIDS
- On the Systematics of Colloids 162
-
THERMODYNAMICS
- On the Calculation of Chemical Equilibrium from Thermal Measurements 167
- The Osmotic Pressure and Conductivity of Aqueous Solutions of Congo-Red, and Reversible Membrane Equilibria 173
- The Production of Temperatures below One Degree Absolute by Adiabatic Demagnetization of Gadolinium Sulfate 176
-
ELECTROLYTES
- The Dissociation of Strong Electrolytes 181
- The Activity Coefficient of Strong Electrolytes 188
- Report on Conductivity of Strong Electrolytes in Dilute Solutions 191
-
ACIDS, BASES, AND SALTS
- The Constitution of Ampholytes, Especially the Amino Acids, and Their Dissociation Constants 198
- Some Remarks on the Concept of Acids and Bases 204
- The Constitution of Acids and Salts and Their Chemical Alterations by Solvents 207
-
CHEMICAL KINETICS
- A Theory of Photochemical Reaction Velocities 213
- The Oxidation of Phosphorus Vapor at Low Pressure 216
- The Activated Complex in Chemical Reactions 219
- The Preparation of Free Methyl 222
-
ARTIFICIAL RADIOACTIVITY
- I. Artificial Production of Radioactive Elements. II. Chemical Proof of Transmutation of Elements 226
- Process for the Production of Radioactive Substances 234
- The Detection and Behavior of the Alkaline Earth Metals Which Result from the Irradiation of Uranium by Neutrons 240
- Disintegration of Uranium by Neutrons. A New Type of Nuclear Reaction 244
- Radioactive Element 93 246
- Radioactive Element 94 from Deuterons on Uranium 249
- Radioactive Element 94 from Deuterons on Uranium 250
- The Chemical Properties of Elements 94 and 93 251
-
Part III Organic Chemistry
-
SYNTHETIC METHODS
- Some New Organometallic Compounds of Magnesium and Their Application to the Synthesis of Alcohols and Hydrocarbons 253
- The “Diene Synthesis,” an Ideal Synthetic Principle for Organic Substances 256
-
POLYMERS
- On Polymerization 259
- On the Constitution of Rubber (Sixth Paper) 264
- Studies on Polymerization and Ring Formation. I. An Introduction to the General Theory of Condensation Polymers 265
-
NATURAL COMPOUNDS
-
Proteins
- Proteins and Polypeptides 268
-
NUCLEIC ACIDS
- Yeast Nucleic Acid 276
-
Alkaloids
- A Theory of the Mechanism of the Phytochemical Synthesis of Certain Alkaloids 276
-
LARGE RINGS
- Knowledge of Carbon Rings. II. Synthesis of Carbocyclic Ketones with Ten- to Eighteen-member Rings 283
-
CHOLESTEROL COMPOUNDS
- Studies on the Constitution of the Bile Acids. XXXIX. Concerning 12-Hydroxycholanic Acid 287
- The Chemistry of the Sex Hormones 294
-
PORPHYRINS
- Hemin and Porphyrins 297
-
CAROTENOIDS AND VITAMIN A
- The Chemistry of Vitamins A and С 302
-
Part IV. Biochemistry
-
HORMONES AND VITAMINS
- The Mechanism of Pancreatic Secretion 311
- The Croonian Lectures on the Chemical Correlation of the Functions of the Body 313
- Feeding Experiments Illustrating the Importance of Accessory Factors in Normal Dietaries 317
-
ENZYMES AND NUCLEOPROTEINS
- The Isolation and Crystallization of the Enzyme Urease. Preliminary Paper 322
- Crystalline Pepsin. I. Isolation and Tests of Purity 327
- Isolation of a Crystalline Protein Possessing the Properties of Tobacco-mosaic Virus 333
-
Biological Oxidations
- The Action of Carbon Monoxide on the Metabolism of Yeast 335
- The Mechanism of Oxidation Processes 336
- Cytochrome and Intracellular Respiratory Enzymes 340
-
FAT METABOLISM
- The Degradation of Aromatic Fatty Acids in the Animal Body 342
- Deuterium as an Indicator in the Study of Intermediary Metabolism. III The Role of the Fat Tissues 346
-
PROTEINS
-
METABOLISM
- The Degradation and Formation of Amino Acids by Transamination. I Exchange of 1(+) Glutamic Acid in Muscle Tissue 354
-
DETERMINATION OF STRUCTURE
- The Free Amino Groups of Insulin 357
-
CARBOHYDRATE METABOLISM
-
Anaerobic Phase
- The Alcoholic Ferment of Yeast-juice 359
- The Alcoholic Ferment of Yeast-Juice. Part II–The Coferment of Yeast-Juice 365
- The Alcoholic Ferment of Yeast-Juice. Part III–The Function of Phosphates in the Fermentation of Glucose by Yeast-Juice 366
- The Pyrophosphate Fraction in Muscle 367
- Phosphorus Compounds of Muscle and Liver 369
- On Intermediate Behavior in Glycolysis in the Musculature 370
- Glycogen Breakdown and Synthesis in Animal Tissues 375
-
MECHANISM OF ENERGY UTILIZATION AND PRODUCTION
- Myosine and Adenosinetriphosphatase 378
- Metabolic Generation and Utilization of Phosphate Bond Energy 381
-
AEROBIC PHASE
- The Role of Citric Acid in Intermediate Metabolism in Animal Tissues 383
-
Biographies. Index
- Bibliography of Biographies 393
- Name Index 403
Chapters in this book
- Frontmatter i
- General Editor’s Preface v
- Preface vii
- Contents xi
- Introduction 1
-
Part I. Techniques
-
ANALYTICAL METHODS
-
Microanalysis
- On Microchemistry, with Special Attention to the Work of H. Behrens 3
- Quantitative Organic Microanalysis 6
-
PHYSIOCHEMICAL ANALYSIS
- The Inner Friction of Binary Mixtures. Characteristics of Definite Compounds 8
-
POLAROGRAPHY
- The Processes at the Mercury Dropping Cathode. Part I. The Deposition of Metals 10
-
Hydrogen Ion Concentration; pH
- Enzyme Studies II. The Measurement and Meaning of Hydrogen Ion Concentration in Enzymatic Processes 16
-
OPTICAL METHODS
-
The Ultramicroscope
- On Making Visible and Determining the Size of Ultramicroscopic2 Particles with Special Attention to Gold Ruby Glasses 19
-
METHODS OF SEPARATION
-
CHROMATOGRAPHY
- Physical Chemical Studies on Chlorophyll. Adsorptions 22
- Qualitative Analysis of Proteins: A Partition Chromatographic Method Using Paper 28
- The Separation of Rare Earths by Ion Exchange. I. Cerium and Yttrium 30
-
SEPARATIONS OF PROTEINS BY SEDIMENTATION AND ELECTROPHORESIS
- Determination of the Size and Distribution of Size of Particles by Centrifugal Methods 31
- Sedimentation of Molecules in Centrifugal Fields 35
- A New Apparatus for Electrophoretic Analysis of Colloidal Mixtures 42
-
RADIOACTIVE TRACERS
- The Absorption and Translocation of Lead by Plants. A Contribution to the Application of the Method of Radioactive Indicators in the Investigation of the Change of Substance in Plants 48
- Radioactive Indicators in the Study of Phosphorus Metabolism in Rats 50
-
CRYSTAL STRUCTURE
- Interference Phenomena in Roentgen Rays 53
- The Reflection of X-Rays by Crystals 54
-
Part II. General and Physical Chemistry
-
ATOMIC AND MOLECULAR STRUCTURE
-
RADIOACTIVE DECAY SERIES
- Radioactive Transformations and the Periodic System of the Elements 67
- The Radio-Elements and the Periodic Law 75
-
ISOTOPES
- The Atomic Weight of Lead of Radioactive Origin 78
- The Atomic Weight of Lead from Pitchblende 82
- The Constitution of Atmospheric Neon 84
- A Hydrogen Isotope of Mass 2 91
-
MOLECULAR STRUCTURE
- Molecule Formation as a Question of Atomic Structure 93
- The Atom and the Molecule 100
- The Arrangement of Electrons in Atoms and Molecules 107
- Polarity and Ionization from the Standpoint of the Lewis Theory of Valence 110
- Co-ordination Compounds 112
-
DIPOLE MOMENTS
- Some Results of a Kinetic Theory of Insulators (Preliminary Communication) 116
-
SPREADING OF FILMS ON LIQUIDS
- The Constitution and Fundamental Properties of Solids and Liquids. II Liquids 123
-
APPLICATION OF QUANTUM MECHANICS
- Significance of Tautomerism and of the Reactions of Aromatic Compounds in the Electronic Theory of Organic Reactions 131
- The New Quantum Mechanics 141
- Wave Mechanics and the Normal State of the Hydrogen Molecule 151
- The Nature of the Chemical Bond. V The Quantum Mechanical Calculation of the Resonance Energy of Benzene and Naphthalene and the Hydrocarbon Free Radicals 156
-
PHYSICAL CHEMISTRY
-
COLLOIDS
- On the Systematics of Colloids 162
-
THERMODYNAMICS
- On the Calculation of Chemical Equilibrium from Thermal Measurements 167
- The Osmotic Pressure and Conductivity of Aqueous Solutions of Congo-Red, and Reversible Membrane Equilibria 173
- The Production of Temperatures below One Degree Absolute by Adiabatic Demagnetization of Gadolinium Sulfate 176
-
ELECTROLYTES
- The Dissociation of Strong Electrolytes 181
- The Activity Coefficient of Strong Electrolytes 188
- Report on Conductivity of Strong Electrolytes in Dilute Solutions 191
-
ACIDS, BASES, AND SALTS
- The Constitution of Ampholytes, Especially the Amino Acids, and Their Dissociation Constants 198
- Some Remarks on the Concept of Acids and Bases 204
- The Constitution of Acids and Salts and Their Chemical Alterations by Solvents 207
-
CHEMICAL KINETICS
- A Theory of Photochemical Reaction Velocities 213
- The Oxidation of Phosphorus Vapor at Low Pressure 216
- The Activated Complex in Chemical Reactions 219
- The Preparation of Free Methyl 222
-
ARTIFICIAL RADIOACTIVITY
- I. Artificial Production of Radioactive Elements. II. Chemical Proof of Transmutation of Elements 226
- Process for the Production of Radioactive Substances 234
- The Detection and Behavior of the Alkaline Earth Metals Which Result from the Irradiation of Uranium by Neutrons 240
- Disintegration of Uranium by Neutrons. A New Type of Nuclear Reaction 244
- Radioactive Element 93 246
- Radioactive Element 94 from Deuterons on Uranium 249
- Radioactive Element 94 from Deuterons on Uranium 250
- The Chemical Properties of Elements 94 and 93 251
-
Part III Organic Chemistry
-
SYNTHETIC METHODS
- Some New Organometallic Compounds of Magnesium and Their Application to the Synthesis of Alcohols and Hydrocarbons 253
- The “Diene Synthesis,” an Ideal Synthetic Principle for Organic Substances 256
-
POLYMERS
- On Polymerization 259
- On the Constitution of Rubber (Sixth Paper) 264
- Studies on Polymerization and Ring Formation. I. An Introduction to the General Theory of Condensation Polymers 265
-
NATURAL COMPOUNDS
-
Proteins
- Proteins and Polypeptides 268
-
NUCLEIC ACIDS
- Yeast Nucleic Acid 276
-
Alkaloids
- A Theory of the Mechanism of the Phytochemical Synthesis of Certain Alkaloids 276
-
LARGE RINGS
- Knowledge of Carbon Rings. II. Synthesis of Carbocyclic Ketones with Ten- to Eighteen-member Rings 283
-
CHOLESTEROL COMPOUNDS
- Studies on the Constitution of the Bile Acids. XXXIX. Concerning 12-Hydroxycholanic Acid 287
- The Chemistry of the Sex Hormones 294
-
PORPHYRINS
- Hemin and Porphyrins 297
-
CAROTENOIDS AND VITAMIN A
- The Chemistry of Vitamins A and С 302
-
Part IV. Biochemistry
-
HORMONES AND VITAMINS
- The Mechanism of Pancreatic Secretion 311
- The Croonian Lectures on the Chemical Correlation of the Functions of the Body 313
- Feeding Experiments Illustrating the Importance of Accessory Factors in Normal Dietaries 317
-
ENZYMES AND NUCLEOPROTEINS
- The Isolation and Crystallization of the Enzyme Urease. Preliminary Paper 322
- Crystalline Pepsin. I. Isolation and Tests of Purity 327
- Isolation of a Crystalline Protein Possessing the Properties of Tobacco-mosaic Virus 333
-
Biological Oxidations
- The Action of Carbon Monoxide on the Metabolism of Yeast 335
- The Mechanism of Oxidation Processes 336
- Cytochrome and Intracellular Respiratory Enzymes 340
-
FAT METABOLISM
- The Degradation of Aromatic Fatty Acids in the Animal Body 342
- Deuterium as an Indicator in the Study of Intermediary Metabolism. III The Role of the Fat Tissues 346
-
PROTEINS
-
METABOLISM
- The Degradation and Formation of Amino Acids by Transamination. I Exchange of 1(+) Glutamic Acid in Muscle Tissue 354
-
DETERMINATION OF STRUCTURE
- The Free Amino Groups of Insulin 357
-
CARBOHYDRATE METABOLISM
-
Anaerobic Phase
- The Alcoholic Ferment of Yeast-juice 359
- The Alcoholic Ferment of Yeast-Juice. Part II–The Coferment of Yeast-Juice 365
- The Alcoholic Ferment of Yeast-Juice. Part III–The Function of Phosphates in the Fermentation of Glucose by Yeast-Juice 366
- The Pyrophosphate Fraction in Muscle 367
- Phosphorus Compounds of Muscle and Liver 369
- On Intermediate Behavior in Glycolysis in the Musculature 370
- Glycogen Breakdown and Synthesis in Animal Tissues 375
-
MECHANISM OF ENERGY UTILIZATION AND PRODUCTION
- Myosine and Adenosinetriphosphatase 378
- Metabolic Generation and Utilization of Phosphate Bond Energy 381
-
AEROBIC PHASE
- The Role of Citric Acid in Intermediate Metabolism in Animal Tissues 383
-
Biographies. Index
- Bibliography of Biographies 393
- Name Index 403