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Biologically Active Tin Compounds Based on Aziridine and Azepane Derivatives

  • H. El-Sharkawy Ali
Published/Copyright: March 31, 2013
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Tenside Surfactants Detergents
From the journal Tenside Surfactants Detergents Volume 45 Issue 2

Abstract

Four of new tin(IV) compounds derived from aziridine and azepane substituents have been synthesized and characterization by elemental microanalysis, atomic absorption, FT-IR and 1H-NMR spectroscopy. These tin-derived compounds exhibited biocidal activities on four different microorganisms: Escherichia coli, Staphylococcus aureus, Candida albicans and Aspergillus niger. The use of common and effective biocides depends on the surfactant molecules. On this basis, surface tension measurements were used to determine the critical micellar concentration (cmc), the minimum average area per surfactant molecule (Amin) and the surface excess concentration (Γ∞). A direct relationship has found between the antimicrobial efficacy and Γ∞.

Kurzfassung

Vier von neuen Zinn(IV)-Verbindungen, derivatisiert aus Aziridin- und Azepan-Substituenten, wurden synthetisiert und mittels elementarer Mikroanalyse, Atomabsorption, FT-IR- und 1H-NMR-Spekroskopie charakterisiert. Diese zinnderivatisierten Verbindungen zeigen eine biozide Aktivität auf vier verschiedene Mikroorganismen: Escherichia coli, Staphylococcus aureus, Candida albicans und Aspergillus niger. Die allgemeine Anwendung und Biozideffektivität ist abhängig von den Tensidmolekülen. Aufgrund dessen wurden Messungen von Oberflächenspannungen genutzt, um die kritische Mizellbildungskonzentration (cmc), die Minimumdurchschnittsfläche pro Tensidmolekül (Amin) und die Oberflächenüberschusskonzentration (Γ∞) zu bestimmen. Dabei wurde ein direkter Zusammenhang zwischen der antimikrobiellen Wirksamkeit und Γ∞ gefunden.

Key words:: Nitrogen heterocycles; aziridine and azepane derivatives; critical micelle concentration; surface tension; antimicrobial activity of surfactants
Stichwörter:: Stickstoffheterozyklus; Aziridin- und Azepan-Derivate; kritische Mizellbildungskonzentration; Oberflächenspannung; antimikrobielle Aktivität von Tensiden
∗ Hanan El-Sharkawy Ali, Petrochemicals Department, Egyptian Petroleum Research Institute (EPRT), Nasr City, Cairo, Egypt. E-mail:

Hanan El-Sharkawy Ali Ahmed is a doctor in the Surfactant Laboratory, Petrochemicals Department, Egyptian Petroleum Research Institute (EPRI). She earned her Ph.D. in Organic Chemistry in 2003, and her M.Sc. in Organic Chemistry in 1999, both from the College of Women, Ain Shams University, Cairo, Egypt. Her experience includes working as an instructor in the field of instrumental analysis, surfactants, petrochemicals and advanced organic chemistry; bioremediation and waste water; bioremediation and crude oil; microorganisms and environmental effects; metal complexes, antimicrobial activity and anti-tumors; chemical reactions and synthesis (PTC/OH); surfactants and surface tension measurements; and instrumental analysis with UV & IR.

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Received: 2007-10-30
Published Online: 2013-03-31
Published in Print: 2008-03-01

© 2008, Carl Hanser Publisher, Munich

Articles in the same Issue

  1. Contents/Inhalt
  2. Contents
  3. Abstracts
  4. Abstracts
  5. Application
  6. Impact of Heat Treatment on the Performance of Polymers as Ferric Ions Stabilization Agents for Aqueous Systems
  7. Novel Surfactants
  8. Preparation and Performance Properties of a Series of Novel Anionic Gemini Surfactants
  9. Biologically Active Tin Compounds Based on Aziridine and Azepane Derivatives
  10. Obituary
  11. Obituary
  12. Synthesis
  13. Synthesis and Properties Evaluation of Nonionic-Anionic Surfactants Suitable for Enhanced Oil Recovery Using Sea Water
  14. Synthesis and Characterisation of Antifungal Agents Containing Copper(II) Soaps and Derived from Mustard and Soyabean Oil
https://doi.org/10.3139/113.100364
Keywords for this article
Nitrogen heterocycles; aziridine and azepane derivatives; critical micelle concentration; surface tension; antimicrobial activity of surfactants

Articles in the same Issue

  1. Contents/Inhalt
  2. Contents
  3. Abstracts
  4. Abstracts
  5. Application
  6. Impact of Heat Treatment on the Performance of Polymers as Ferric Ions Stabilization Agents for Aqueous Systems
  7. Novel Surfactants
  8. Preparation and Performance Properties of a Series of Novel Anionic Gemini Surfactants
  9. Biologically Active Tin Compounds Based on Aziridine and Azepane Derivatives
  10. Obituary
  11. Obituary
  12. Synthesis
  13. Synthesis and Properties Evaluation of Nonionic-Anionic Surfactants Suitable for Enhanced Oil Recovery Using Sea Water
  14. Synthesis and Characterisation of Antifungal Agents Containing Copper(II) Soaps and Derived from Mustard and Soyabean Oil
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