Article
Licensed
Unlicensed
Requires Authentication
Exposure to Oscillating High Electrical Potential and the Associated Low Frequency Magnetic Field Enhances the Hepatoprotective Action of Schisandrin B in Vivo and in Vitro
-
Kam Ming Ko
Published/Copyright:
August 31, 2009
The effect of electromagnetic manipulation (EM), consisting of an oscillating (50 Hz) high electrical potential (a maximum value of 20,000 V and an output current < 100 µA) and its associated alternating magnetic field (50-60 Guass), on the hepatoprotective action of schisandrin B (Sch B, an active ingredient isolated from the fruit of Schisandra chinensis) was examined in the mouse model of carbon tetrachloride (CCl4) hepatotoxicity and the AML12 cell model of menadione-induced toxicity. EM was found to enhance the Sch B-induced hepatoprotective action against CCl4 toxicity in mice and cytoprotective action against menadione toxicity in AML12 hepatocytes. The potentiating effect of EM on the pharmacological action of Sch B may be mediated by the increase in drug availability to tissues or cells and/or the pro-oxidant action of electromagnetic field in vivo.
Keywords: high electrical potential; low frequency magnetic field; schisandrin B; carbon tetrachloride; liver; menadione; AML12
Published Online: 2009-8-31
©2011 Walter de Gruyter GmbH & Co. KG, Berlin/Boston
You are currently not able to access this content.
You are currently not able to access this content.
Articles in the same Issue
- Research Article
- Action of Portulaca oleracea against Streptozotocin-Induced Oxidative Stress in Experimental Diabetic Rats
- Effect of Naga Parpam, a Zinc-Based Siddha Medicine, on Hyperlipidemia in Rats
- The Organizational Support Necessary for Integrative Health Care (IHC): A Clinic for Artists in a Hospital Setting
- Investigation of Antihyperglycemic Activity of Glycine max (L.) Merr. on Serum Glucose Level in Diabetic Mice
- Aldose Reductase Inhibitory Activity of a C-glycosidic Flavonoid Derived from Enicostemma hyssopifolium
- Exploring Antidiabetic Mechanisms of Action of Galactomannan: A Carbohydrate Isolated from Fenugreek Seeds
- The Potential Role of Daucus carota Aqueous and Methanolic Extracts on Inflammation and Gastric Ulcers in Rats
- Free Radical Scavenging Activity and Inhibitory response of Ziziphus mauritiana (Lamk.) Seed Extract on Alcohol-Induced Oxidative Stress
- Antibacterial Activity and Anticorrosive Efficiency of Aqueous Methanolic Extract of Artemisia pallens (Asteraceae) and Its Major Constituent
- Ameliorative Role of Vitamin E on Adverse Impact of Azadirachta indica in Reproductive Indices of Male Rats
- Biphasic Modulation of Neutrophil Migration by Aqueous Extracts of Uncaria tomentosa in Murine Lung
- In Vitro Evaluation of Antioxidant and Free Radical Scavenging Activities of Rhodiola imbricata
- The Effect of Tai Chi in Reducing Anxiety in an Ambulatory Population
- Antidiarrhoeal Activity of Pterocarpus santalinoides L'Hérit ex DC Leaf Extract
- Phytochemical Constituents and Free Radical Scavenging Activity of Clerodendron glandulosum.Coleb Methanolic Extract
- Anti-Nociceptive and Anti-Inflammatory Activities of Extracts from the Stem Bark of Croton macrostachyus (Euphorbiaceae) in Mice and Rats
- Protective Effect of Red Wine Extract Supplement against Myocardial Ischemia/Reperfusion Injury in Rats: Effects on Mitochondrial Antioxidant and Structural Parameters
- Effect on Inhibition of Proliferation and Antioxidant Enzyme Level of Lippia nodiflora in EAC Cell Line Treated Mice
- Exposure to Oscillating High Electrical Potential and the Associated Low Frequency Magnetic Field Enhances the Hepatoprotective Action of Schisandrin B in Vivo and in Vitro
- Assessment of in Vitro Antioxidant and Free Radical Scavenging Activity of Cajanus cajan
- Antiproliferative, Antioxidant and Cyto/DNA Protective Properties in Andrographis serpyllifolia: Role of Andrographolide and Phenolic Acids
- Caudal Epididymal Sperm Characteristics and Testicular Morphometrics of Rabbits Fed Graded Levels of a Blood-Wild Sunflower Leaf Meal (BWSLM) Mixture Diet
- Probable Mechanism of the Antihyperglycemic Effect of Standardized Extract from Momordica charantia in Streptozotocin Diabetic Rats
- Effect of Citrullus colocynthis Schard on Testosterone-Induced Benign Prostatic Hyperplasia
- Static Electric Field by High Voltage Alternating Current Ameliorates Collagen-Induced Arthritis in Mice via the Inhibition of IL-1? Expression
- Effects of R-Alpha Lipoic Acid on HbA1c, Lipids and Blood Pressure in Type-2 Diabetics: A Preliminary Study
- Complementary or Alternative--Does It Matter In Your Questionnaire?
- Globularia alypum L. Lyophilized Methanolic Extract Decreases Hyperglycemia and Improves Antioxidant Status in Various Tissues of Streptozotocin-Induced Diabetic Rats
- Determination of Phenolic Content of Cassia sophera Linn. and the Potential Antiulcer Activity in Experimentally Induced Ulceration
- Augmentation of Antioxidant Defense System by Tinospora cordifolia: Implications in Radiation Protection
- Hepatoprotective Evaluation of Scoparia dulcis L.
- Discussion Paper
- Methodological Issues Pertaining to the Evaluation of the Effectiveness of Energy-Based Therapies, Avenues for a Methodological Guide
- Is All Glucosamine Alike? Clarifying the Controversies for Product Selection and Clinical Research
- Review Article
- Using the Biopsychosocial Model to Understand the Health Benefits of Yoga
- A Review of Side Effects and Adverse Events of Non-Drug Medicine (Nonpharmaceutical Complementary and Alternative Medicine): Psychotherapy, Mind-Body Medicine and Clinical Holistic Medicine
- Augmentation of Mind-body Therapy and Role of Deep Slow Breathing
- Short Communication on Medicinal Herbs
- Protective Role of Pterocarpus marsupium in Diabetes-Induced Hyperlipidemic Condition
Keywords for this article
high electrical potential;
low frequency magnetic field;
schisandrin B;
carbon tetrachloride;
liver;
menadione;
AML12
Articles in the same Issue
- Research Article
- Action of Portulaca oleracea against Streptozotocin-Induced Oxidative Stress in Experimental Diabetic Rats
- Effect of Naga Parpam, a Zinc-Based Siddha Medicine, on Hyperlipidemia in Rats
- The Organizational Support Necessary for Integrative Health Care (IHC): A Clinic for Artists in a Hospital Setting
- Investigation of Antihyperglycemic Activity of Glycine max (L.) Merr. on Serum Glucose Level in Diabetic Mice
- Aldose Reductase Inhibitory Activity of a C-glycosidic Flavonoid Derived from Enicostemma hyssopifolium
- Exploring Antidiabetic Mechanisms of Action of Galactomannan: A Carbohydrate Isolated from Fenugreek Seeds
- The Potential Role of Daucus carota Aqueous and Methanolic Extracts on Inflammation and Gastric Ulcers in Rats
- Free Radical Scavenging Activity and Inhibitory response of Ziziphus mauritiana (Lamk.) Seed Extract on Alcohol-Induced Oxidative Stress
- Antibacterial Activity and Anticorrosive Efficiency of Aqueous Methanolic Extract of Artemisia pallens (Asteraceae) and Its Major Constituent
- Ameliorative Role of Vitamin E on Adverse Impact of Azadirachta indica in Reproductive Indices of Male Rats
- Biphasic Modulation of Neutrophil Migration by Aqueous Extracts of Uncaria tomentosa in Murine Lung
- In Vitro Evaluation of Antioxidant and Free Radical Scavenging Activities of Rhodiola imbricata
- The Effect of Tai Chi in Reducing Anxiety in an Ambulatory Population
- Antidiarrhoeal Activity of Pterocarpus santalinoides L'Hérit ex DC Leaf Extract
- Phytochemical Constituents and Free Radical Scavenging Activity of Clerodendron glandulosum.Coleb Methanolic Extract
- Anti-Nociceptive and Anti-Inflammatory Activities of Extracts from the Stem Bark of Croton macrostachyus (Euphorbiaceae) in Mice and Rats
- Protective Effect of Red Wine Extract Supplement against Myocardial Ischemia/Reperfusion Injury in Rats: Effects on Mitochondrial Antioxidant and Structural Parameters
- Effect on Inhibition of Proliferation and Antioxidant Enzyme Level of Lippia nodiflora in EAC Cell Line Treated Mice
- Exposure to Oscillating High Electrical Potential and the Associated Low Frequency Magnetic Field Enhances the Hepatoprotective Action of Schisandrin B in Vivo and in Vitro
- Assessment of in Vitro Antioxidant and Free Radical Scavenging Activity of Cajanus cajan
- Antiproliferative, Antioxidant and Cyto/DNA Protective Properties in Andrographis serpyllifolia: Role of Andrographolide and Phenolic Acids
- Caudal Epididymal Sperm Characteristics and Testicular Morphometrics of Rabbits Fed Graded Levels of a Blood-Wild Sunflower Leaf Meal (BWSLM) Mixture Diet
- Probable Mechanism of the Antihyperglycemic Effect of Standardized Extract from Momordica charantia in Streptozotocin Diabetic Rats
- Effect of Citrullus colocynthis Schard on Testosterone-Induced Benign Prostatic Hyperplasia
- Static Electric Field by High Voltage Alternating Current Ameliorates Collagen-Induced Arthritis in Mice via the Inhibition of IL-1? Expression
- Effects of R-Alpha Lipoic Acid on HbA1c, Lipids and Blood Pressure in Type-2 Diabetics: A Preliminary Study
- Complementary or Alternative--Does It Matter In Your Questionnaire?
- Globularia alypum L. Lyophilized Methanolic Extract Decreases Hyperglycemia and Improves Antioxidant Status in Various Tissues of Streptozotocin-Induced Diabetic Rats
- Determination of Phenolic Content of Cassia sophera Linn. and the Potential Antiulcer Activity in Experimentally Induced Ulceration
- Augmentation of Antioxidant Defense System by Tinospora cordifolia: Implications in Radiation Protection
- Hepatoprotective Evaluation of Scoparia dulcis L.
- Discussion Paper
- Methodological Issues Pertaining to the Evaluation of the Effectiveness of Energy-Based Therapies, Avenues for a Methodological Guide
- Is All Glucosamine Alike? Clarifying the Controversies for Product Selection and Clinical Research
- Review Article
- Using the Biopsychosocial Model to Understand the Health Benefits of Yoga
- A Review of Side Effects and Adverse Events of Non-Drug Medicine (Nonpharmaceutical Complementary and Alternative Medicine): Psychotherapy, Mind-Body Medicine and Clinical Holistic Medicine
- Augmentation of Mind-body Therapy and Role of Deep Slow Breathing
- Short Communication on Medicinal Herbs
- Protective Role of Pterocarpus marsupium in Diabetes-Induced Hyperlipidemic Condition
