Update in Pre-Clinical Regulatory Requirements for Phytomedicines in Latin America
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Diadelis Caridad Remirez
The use of herbal medicines or natural health products as alternative medicines for public health use continues to expand rapidly around the world. Pre-clinical assays are essential to guarantee the efficacy and safety of natural products and are commonly requested by regulatory agencies to approve marketing of these products. Different animal models are used to evaluate the pharmacological effects of natural health products and herbal medicines in particular. The main toxicological assays and pharmacological activities to be tested in the evaluation of natural products will be discussed in this presentation. Common pharmacological effects of herbal medicines are: anti inflammatory, antioxidative, hepatoprotective, laxative and analgesic. The importance of using positive and negative controls will be explained and examples will be provided. Animal models currently used in the evaluation of herbal medicines will be presented and the importance of selecting the right model to reproduce human disorders will be highlighted.
©2011 Walter de Gruyter GmbH & Co. KG, Berlin/Boston
Articles in the same Issue
- Discussion Paper
- Integrative Health Care: a Need for Change?
- Research Article
- Use of Complementary and Alternative Medicine by Chinese Individuals Living with Cancer in British Columbia
- Update in Pre-Clinical Regulatory Requirements for Phytomedicines in Latin America
- Spirituality and Adaptive Coping Styles in German Patients with Chronic Diseases in a CAM Health Care Setting
- Complementary/Alternative Medicine in Latin America: Use of Herbal Remedies among a Brazilian Metropolitan Area Population
- The Effects of a Decoction Prepared from the Leaves and Unripe Fruits of Crataegus aronia in Streptozotocin-Induced Diabetic Rats
- Protective Effects of Silymarin against Free Radical-Induced Erythrocyte Lysis
- Conference Presentation
- Integrating CAM Research and Practice: A Focus on Outcome Measures - Abstracts from the 3rd Annual IN-CAM Symposium November 4th & 5th, 2006, Calgary, Canada
Articles in the same Issue
- Discussion Paper
- Integrative Health Care: a Need for Change?
- Research Article
- Use of Complementary and Alternative Medicine by Chinese Individuals Living with Cancer in British Columbia
- Update in Pre-Clinical Regulatory Requirements for Phytomedicines in Latin America
- Spirituality and Adaptive Coping Styles in German Patients with Chronic Diseases in a CAM Health Care Setting
- Complementary/Alternative Medicine in Latin America: Use of Herbal Remedies among a Brazilian Metropolitan Area Population
- The Effects of a Decoction Prepared from the Leaves and Unripe Fruits of Crataegus aronia in Streptozotocin-Induced Diabetic Rats
- Protective Effects of Silymarin against Free Radical-Induced Erythrocyte Lysis
- Conference Presentation
- Integrating CAM Research and Practice: A Focus on Outcome Measures - Abstracts from the 3rd Annual IN-CAM Symposium November 4th & 5th, 2006, Calgary, Canada
