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The approach of the joint probability distribution functions: the SIR-MIR, SAD-MAD and SIRAS-MIRAS, cases
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C. Giacovazzo
Published/Copyright:
September 25, 2009
Abstract
The method of the joint probability distribution functions has been recently applied to SIR-MIR, SAD-MAD and SIRAS-MIRAS cases. The capacity of the method to treat various forms of errors (i.e., errors in measurements, possible lack of isomorphism, errors in a substructure model when a model is a priori available, etc.) is the most innovative aspect of the approach. The description of the technique and the analysis of the conclusive formulas are dispersed in a number of papers; this contribution offers a unified point of view for all the cases and a perspective for future applications.
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Published Online: 2009-9-25
Published in Print: 2002-12-1
© 2002 Oldenbourg Wissenschaftsverlag GmbH
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Articles in the same Issue
- Preface: Macromolecular Crystallography
- More power for direct methods: SIR2002
- ACORN — theory and practice
- Macromolecular phasing with SHELXE
- Physical measurement of triplet invariants: present state of the experiment, data evaluation and future perspectives
- Qantitative determination of phase for macromolecular crystals using multiple diffraction methods and dynamical theory
- Ab initio phasing starting from low resolution
- Towards automated protein structure determination: BnP, the SnB-PHASES interface
- Direct way to anomalous scatterers
- The approach of the joint probability distribution functions: the SIR-MIR, SAD-MAD and SIRAS-MIRAS, cases
- Direct-method phasing of anomalous diffraction from proteins
- Molecular replacement and high-throughput structure determination