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Improved targetry and production of iodine-124 for PET studies
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Matthias Glaser
Published/Copyright:
September 25, 2009
Summary
Iodine-124 (T1/2=4.18 d) is an important radionuclide for preclinical research in positron emission tomography (PET). We describe an improved method to produce and extract 124I from a solid [124Te]TeO2 target efficiently using the dry distillation technique. Our process is based on remote hot cell handling and was optimised to achieve efficiencies better than 90% with an average thick target yield of 9.0±1.0 MBq/μAh (n=47, corrected for decay). The technology is safe and reduces the dose to the operator.
Published Online: 2009-9-25
Published in Print: 2004-12-1
© 2004 Oldenbourg Wissenschaftsverlag GmbH
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- Evidence for the formation of sodium hassate(VIII)
- Study of nitrate complex formation with trivalent Pm, Eu, Am and Cm using a solvent extraction technique
- Hydrolysis of Np(IV) and Pu(IV) and their complexation by aqueous Si(OH)4
- Reduction kinetics of Np(VI) by n-butyraldehyde in tributyl phosphate diluted with n-dodecane
- Speciation study on complex formation of uranium(VI) with phosphate and fluoride at high temperatures and pressures by time-resolved laser-induced fluorescence spectroscopy
- Stability constants of uranium(IV)-α-isosaccharinic acid and gluconic acid complexes
- Uranium(VI) complexes with sugar phosphates in aqueous solution
- Uranium kernel formation via internal gelation
- Investigation of evaporation characteristics of polonium and its lighter homologues selenium and tellurium from liquid Pb-Bi-eutecticum
- Synergistic extraction of Ce(III), Eu(III) and Tm(III) with a mixture of picrolonic acid and tributylphosphine oxide in chloroform
- Synthesis of malonic acid-functionalized Amberlite XAD-4 and its use in solid phase extraction/preconcentrative separation of thorium(IV)
- INAA methodology using low power reactor for the characterization of IAEA-433; Coastal marine sediment as a potential reference material
- Determination of natural radioactivity in building materials used in the Karachi area by γ-ray spectrometry and INAA
- Improved targetry and production of iodine-124 for PET studies
