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Model of the human endocrine system regulatory network. Mechanisms and equations
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A. A. Romanyukha
Published/Copyright:
August 13, 2007
This paper is devoted to the construction of a mathematical model of the endocrine system regulatory network. The model describes interdependence between the concentrations of forty-five hormones, carrier proteins, their complexes, and several physiological parameters. The integrated network including six endocrine subsystems or axes (somatotropic, gonadotropic, thyroid, hypothalamicpituitary-adrenal axis (HPA axis), mineral-corticoid and the axis of calcium homeostasis) is described. The model can be applied to the investigation of development, aging, long-term adaptation and approaches to correction of unfavorable dynamics of these complex physiological processes.
Published Online: 2007-08-13
Published in Print: 2007-07-20
Copyright 2007, Walter de Gruyter
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Articles in the same Issue
- Experimental verification of a theoretical error estimate for calculation of a response matrix
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- Using the technique of majorant functions in approximation of a singular perturbed parabolic convection–diffusion equation on adaptive grids
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