Sham transcranial electrical stimulation and its effects on corticospinal excitability: a systematic review and meta-analysis

References

Antal, A., Boros, K., Poreisz, C., Chaieb, L., Terney, D., and Paulus, W. (2008). Comparatively weak after-effects of transcranial alternating current stimulation (tACS) on cortical excitability in humans. Brain Stimul. 1, 97–105.10.1016/j.brs.2007.10.001Search in Google Scholar PubMed

Bastani, A. and Jaberzadeh, S. (2013). a-tDCS differential modulation of corticospinal excitability: the effects of electrode size. Brain Stimul. 6, 932–937.10.1016/j.brs.2013.04.005Search in Google Scholar PubMed

Batsikadze, G., Moliadze, V., Paulus, W., Kuo, M.F., and Nitsche, M.A. (2013). Partially non-linear stimulation intensity-dependent effects of direct current stimulation on motor cortex excitability in humans. J. Physiol. 591, 1987–2000.10.1113/jphysiol.2012.249730Search in Google Scholar PubMed

Benedetti, F., Carlino, E., and Piedimonte, A. (2016). Increasing uncertainty in CNS clinical trials: the role of placebo, nocebo, and Hawthorne effects. Lancet Neurol. 15, 736–747.10.1016/S1474-4422(16)00066-1Search in Google Scholar PubMed

Borenstein, M., Hedges, L.V., Higgins, J.P.T., and Rothstein, H.R. (2009). Fixed-effect versus random-effects models. In: Introduction to Meta-Analysis, M. Borenstein, L.V. Hedges, J.P.T. Higgins and H.R. Rothstein, eds. (John Wiley & Sons, Ltd.), pp. 77–86.10.1002/9780470743386.ch13Search in Google Scholar

Brim, R. and Miller, F. (2013). The potential benefits of the placebo effect in sham-controlled trials: implications for risk-benefit assessments and informed consent. J. Med. Ethics 39, 703–707.10.1136/medethics-2012-101045Search in Google Scholar PubMed PubMed Central

Chaieb, L., Antal, A., and Paulus, W. (2011a). Transcranial alternating current stimulation in the low kHz range increases motor cortex excitability. Restor. Neurol. Neurosci. 29, 167–175.10.3233/RNN-2011-0589Search in Google Scholar PubMed

Chaieb, L., Paulus, W., and Antal, A. (2011b). Evaluating after effects of short-duration transcranial random noise stimulation on cortical excitability. Neural Plast. 1–5.10.1155/2011/105927Search in Google Scholar PubMed PubMed Central

Coffman, B.A., Trumbo, M.C., and Clark, V.P. (2012). Enhancement of object detection with transcranial direct current stimulation is associated with increased attention. BMC neuroscience. 13, 108.10.1186/1471-2202-13-108Search in Google Scholar PubMed PubMed Central

Deeks, J. and Higgins, J. (2010). Statistical algorithms in Rewman Manager 5. Cochrane Collaboration [Internet].Search in Google Scholar

Duecker, F. and Sack, A.T. (2015). Rethinking the role of sham TMS. Front. psychol. 6, 210.10.3389/fpsyg.2015.00210Search in Google Scholar PubMed PubMed Central

Dundas, J.E., Thickbroom, G.W., and Mastaglia, F.L. (2007). Perception of comfort during transcranial DC stimulation: effect of NaCl solution concentration applied to sponge electrodes. Clin. Neurophysiol. 118, 1166–1170.10.1016/j.clinph.2007.01.010Search in Google Scholar PubMed

Gandiga, P.C., Hummel, F.C., and Cohen, L.G. (2006). Transcranial DC stimulation (tDCS): a tool for double-blind sham-controlled clinical studies in brain stimulation. Clin. Neurophysiol. 117, 845–850.10.1016/j.clinph.2005.12.003Search in Google Scholar PubMed

Higgins, J.P. and Green, S. (2008). Cochrane Handbook for Systematic Reviews of Interventions. The Cochrane Collaboration, Wiley.10.1002/9780470712184Search in Google Scholar

Higgins, J.P., Thompson, S.G., Deeks, J.J., and Altman, D.G. (2003). Measuring inconsistency in meta-analyses. Br. Med. J. 327, 557–560.10.1136/bmj.327.7414.557Search in Google Scholar PubMed PubMed Central

Hill, A.T., Fitzgerald, P.B., and Hoy, K.E. (2016). Effects of anodal transcranial direct current stimulation on working memory: a systematic review and meta-analysis of findings from healthy and neuropsychiatric populations. Brain Stimul. 9, 197–208.10.1016/j.brs.2015.10.006Search in Google Scholar PubMed

Ho, K.-A., Taylor, J., and Loo, C. (2015). Comparison of the effects of transcranial random noise stimulation and transcranial direct current stimulation on motor cortical excitability. J. ECT 31, 67–72.10.1097/YCT.0000000000000155Search in Google Scholar PubMed

Horvath, J.C., Vogrin, S.J., Carter, O., Cook, M.J., and Forte, J.D. (2016). Effects of a common transcranial direct current stimulation (tDCS) protocol on motor evoked potentials found to be highly variable within individuals over 9 testing sessions. Exp. Brain Res. 234, 2629–2642.10.1007/s00221-016-4667-8Search in Google Scholar PubMed

Hrobjartsson, A., Kaptchuk, T.J., and Miller, F.G. (2011). Placebo effect studies are susceptible to response bias and to other types of biases. J. Clin. Epidemiol. 64, 1223–1229.10.1016/j.jclinepi.2011.01.008Search in Google Scholar PubMed PubMed Central

Inukai, Y., Saito, K., Sasaki, R., Tsuiki, S., Miyaguchi, S., Kojima, s., Masaki, M., Otsuru, N., and Onishi, H. (2016). Comparison of three non-invasive transcranial electrical stimulation methods for increasing cortical excitability. Front. Hum. Neurosci. 10, 1–7.10.3389/fnhum.2016.00668Search in Google Scholar PubMed PubMed Central

Jaberzadeh, S., Bastani, A., and Zoghi, M. (2014). Anodal transcranial pulsed current stimulation: a novel technique to enhance corticospinal excitability. Clin. Neurophysiol. 125, 344–351.10.1016/j.clinph.2013.08.025Search in Google Scholar PubMed

Jaberzadeh, S., Bastani, A., Zoghi, M., Morgan, P., and Fitzgerald, P.B. (2015). Anodal transcranial pulsed current stimulation: the effects of pulse duration on corticospinal excitability. PLoS One 10, 1–14.10.1371/journal.pone.0131779Search in Google Scholar PubMed PubMed Central

Jamil, A., Batsikadze, G., Kuo, H. I., Labruna, L., Hasan, A., Paulus, W., and Nitsche, M.A. (2016). Systematic evaluation of the impact of stimulation intensity on neuroplastic after-effects induced by transcranial direct current stimulation. J. Physiol. 1–16.10.1113/JP272738Search in Google Scholar PubMed PubMed Central

Joseph, A. (2010). Plot digitizer 2.4.1 [Internet], open source software available at http://plotdigitizer.sourceforge.net/.Search in Google Scholar

Kessler, S.K., Turkeltaub, P.E., Benson, J.G., and Hamilton, R.H. (2012). Differences in the experience of active and sham transcranial direct current stimulation. Brain Stimul. 5, 155–162.10.1016/j.brs.2011.02.007Search in Google Scholar PubMed PubMed Central

Kidgell, D.J., Goodwill, A.M., Frazer, A.K., and Daly, R.M. (2013). Induction of cortical plasticity and improved motor performance following unilateral and bilateral transcranial direct current stimulation of the primary motor cortex. BMC Neurosci. 14, 1–12.10.1186/1471-2202-14-64Search in Google Scholar PubMed PubMed Central

Kim, G.W. and Ko, M.H. (2013). Facilitation of corticospinal tract excitability by transcranial direct current stimulation combined with voluntary grip exercise. Neurosci. Lett. 548, 181–184.10.1016/j.neulet.2013.05.037Search in Google Scholar PubMed

Lang, N., Siebner, H.R., Ernst, D., Nitsche, M.A., Paulus, W., Lemon, R.N., and Rothwell, J.C. (2004). Preconditioning with transcranial direct current stimulation sensitizes the motor cortex to rapid-rate transcranial magnetic stimulation and controls the direction of after-effects. Biol. Psychiatry. 56, 634–639.10.1016/j.biopsych.2004.07.017Search in Google Scholar PubMed

Lee, M., Kim, Y.H., Im, C.H., Kim, J.H., Park, C.H., Chang, W.H., and Lee, A. (2015). What is the optimal anodal electrode position for inducing corticomotor excitability changes in transcranial direct current stimulation? Neurosci. Lett. 584, 347–350.10.1016/j.neulet.2014.10.052Search in Google Scholar PubMed

Moliadze, V., Antal, A., and Paulus, W. (2010). Boosting brain excitability by transcranial high frequency stimulation in the ripple range. J. Physiol. 588, 4891–4904.10.1113/jphysiol.2010.196998Search in Google Scholar PubMed PubMed Central

Moliadze, V., Fritzsche, G., and Antal, A. (2014). Comparing the efficacy of excitatory transcranial stimulation methods measuring motor evoked potentials. Neural Plast. 1–6.10.1155/2014/837141Search in Google Scholar PubMed PubMed Central

Moliadze, V., Atalay, D., Antal, A., and Paulus, W. (2012). Close to threshold transcranial electrical stimulation preferentially activates inhibitory networks before switching to excitation with higher intensities. Brain Stimul. 5, 505–511.10.1016/j.brs.2011.11.004Search in Google Scholar PubMed

Nitsche, M.A. and Paulus, W. (2000). Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation. J. Physiol. 527, 633–639.10.1111/j.1469-7793.2000.t01-1-00633.xSearch in Google Scholar PubMed PubMed Central

Nitsche, M., Doemkes, S., Karakose, T., Antal, A., Liebetanz, D., Lang, N., Tergau, F., and Paulus, W. (2007). Shaping the effects of transcranial direct current stimulation of the human motor cortex. J. Neurophysiol. 97, 3109–3117.10.1152/jn.01312.2006Search in Google Scholar PubMed

O’Connell, N.E., Cossar, J., Marston, L., Wand, B.M., Bunce, D., Moseley, G.L., and De Souze, L.H. (2012). Rethinking clinical trials of transcranial direct current stimulation: participant and assessor blinding is inadequate at intensities of 2mA. PloS One. 7, 1–5.10.1371/journal.pone.0047514Search in Google Scholar PubMed PubMed Central

Palm, U., Reisinger, E., Keeser, D., Kuo, M.F., Pogarell, O., Leicht, G., Mulert, C., Nitsche, M.A., and Padberg, F. (2013). Evaluation of Sham Transcranial Direct Current Stimulation for Randomized, Placebo-Controlled Clinical Trials. Brain stimulation. 6, 690–695.10.1016/j.brs.2013.01.005Search in Google Scholar PubMed

Poreisz, C., Boros, K., Antal, A., and Paulus, W. (2007). Safety aspects of transcranial direct current stimulation concerning healthy subjects and patients. Brain Res. Bull. 72, 208–214.10.1016/j.brainresbull.2007.01.004Search in Google Scholar PubMed

Power, H.A., Norton, J.A., Porter, C.L., Doyle, Z., Hui, I., and Chan, K.M. (2006). Transcranial direct current stimulation of the primary motor cortex affects cortical drive to human musculature as assessed by intermuscular coherence. J. Physiol. 577, 795–803.10.1113/jphysiol.2006.116939Search in Google Scholar PubMed PubMed Central

Quartarone, A., Morgante, F., Bagnato, S., Rizzo, V., Sant‘Angelo, A., Aiello, E., Reggio, E., Battaglia, F., Messina, C., and Girlanda, P. (2004). Long lasting effects of transcranial direct current stimulation on motor imagery. Neuroreport. 15, 1287–1291.10.1097/01.wnr.0000127637.22805.7cSearch in Google Scholar PubMed

Santarnecchi, E., Feurra, M., Barneschi, F., Acampa, M., Bianco, G., Cioncoloni, D., Rossi, A., and Rossi, S. (2014). Time course of cortical excitability and autonomic function interplay during and following monopolar tDCS. Front. Psychiatry. 5, 1–11.10.3389/fpsyt.2014.00086Search in Google Scholar PubMed PubMed Central

Sasaki, R., Miyaguchi, S., Kotan, S., Kojima, S., Kirimoto, H., and Onishi, H. (2016). Modulation of cortical inhibitory circuits after cathodal transcranial direct current stimulation over the primary motor cortex. Front. Hum. Neurosci. 10, 1–8.10.3389/fnhum.2016.00030Search in Google Scholar PubMed PubMed Central

Schabrun, S.M., Chipchase, L.S., Zipf, N., Thickbroom, G.W., and Hodges, P.W. (2013). Interaction between simultaneously applied neuromodulatory interventions in humans. Brain Stimul. 6, 624–630.10.1016/j.brs.2012.09.009Search in Google Scholar PubMed

Schade, S., Moliadze, V., Paulus, W., and Antal, A. (2012). Modulating neuronal excitability in the motor cortex with tDCS shows moderate hemispheric asymmetry due to subjects’ handedness: a pilot study. Restor. Neurol. Neurosci. 30, 191–198.10.3233/RNN-2012-110175Search in Google Scholar PubMed

Schmidt, S., Fleischmann, R., Bathe-Peters, R., Irlbacher, K., and Brandt, S.A. (2013). Evolution of premotor cortical excitability after cathodal inhibition of the primary motor cortex: a sham-controlled serial navigated TMS study. PLoS One 8, 1–10.10.1371/journal.pone.0057425Search in Google Scholar PubMed PubMed Central

Siebner, H.R., Lang, N., Rizzo, V., Nitsche, M.A., Paulus, W., Lemon, R.N., and Rothwell, J.C. (2004). Preconditioning of low-frequency repetitive transcranial magnetic stimulation with transcranial direct current stimulation: evidence for homeostatic plasticity in the human motor cortex. J Neurosci. 24, 3379–3385.10.1523/JNEUROSCI.5316-03.2004Search in Google Scholar PubMed PubMed Central

Sterne, J.A., Egger, M., and Smith, G.D. (2001). Systematic reviews in health care: investigating and dealing with publication and other biases in meta-analysis. Br. Med. J. 323, 101–105.10.1136/bmj.323.7304.101Search in Google Scholar PubMed PubMed Central

Straube S, Derry S, McQuay H.J., and Moore R.A. (2008). Enrichedenrollment: definition and effects of enrichment and dose in trials of pregabalin and gabapentin in neuropathic pain. A systematic review. Br. J. Clin. Pharmacol. 66, 266–275.10.1111/j.1365-2125.2008.03200.xSearch in Google Scholar PubMed PubMed Central

Suzuki, K., Fujiwara, T., Tanaka, N., Tsuji, T., Masakado, Y., Hase, K., Kimura, A., and Liu, M. (2012). Comparison of the after-effects of transcranial direct current stimulation over the motor cortex in patients with stroke and healthy volunteers. Int. J. Neurosci. 122, 675–681.10.3109/00207454.2012.707715Search in Google Scholar PubMed

Terney, D., Chaieb, L., Moliadze, V., Antal, A., and Paulus, W. (2008). Increasing human brain excitability by transcranial high-frequency random noise stimulation. J. Neurosci. 28, 14147–14155.10.1523/JNEUROSCI.4248-08.2008Search in Google Scholar PubMed PubMed Central

Vaseghi, B., Zoghi, M., and Jaberzadeh, S. (2015). The effects of anodal-tDCS on corticospinal excitability enhancement and its after-effects: conventional vs. unihemispheric concurrent dual-site stimulation. Front. Hum. Neurosci. 9, 1–13.10.3389/fnhum.2015.00533Search in Google Scholar PubMed PubMed Central

Woods, A.J., Antal, A., Bikson, M., Boggio, P.S., Brunoni, A.R., Celnik, P., Cohen, L.G., Fregni, F., Herrmann, C.S., Kappenman, E.S., et al. (2016). A technical guide to tDCS, and related non-invasive brain stimulation tools. Clin. Neurophysiol. 127, 1031–1048.10.1016/j.clinph.2015.11.012Search in Google Scholar PubMed PubMed Central