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Platinum organometallic compounds: classification and analysis of crystallographic and structural data of monomeric five and higher coordinated

  • Milan Melník

    Prof. Dr. Milan Melník, DrSc graduated from the Comenius University of Bratislava, Slovakia and obtained his PhD (1972) and Doctor of Science (1990) from Slovak Technical University (Slovakia). His main research interest concerns the coordination and bio-coordination chemistry of the transition and main group elements. In his research activities are structure – properties – bioactivities. His research focused on development new drugs on the basis of copper complex – antirheumatics, antituberculotics, with bioactive ligands. He has (co)authored 59 scientific monographs, over 350 scientific papers. He is a member of various universities and leading scientist of many research projects.

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    , Peter Mikuš

    Assoc. Prof. Dr. Peter Mikuš, PhD received his MSc in Analytical Chemistry in 1995 from the Faculty of Natural Sciences Comenius University in Bratislava, Slovak Republic. He received his PhD in Analytical Chemistry from the same Faculty in 2002. Currently, he is Assistant Professor, Head of the Department of Pharmaceutical Analysis and Nuclear Pharmacy and Director of the Toxicological and Antidoping Center. His research interests include development of new progressive (chiral) capillary electrophoresis separation methods for the advanced pharmaceutical and biomedical analyses of drugs, their (bio) degradation products, and biomarkers. Recently his research is also oriented on the crystallography of coordination compounds.

    and Clive Eduard Holloway

    Professor Holloway obtained a MSc and PhD at the University of Western Ontario, and joined the Department of Chemistry, York University, Toronto, Canada in 1968. Research has included the synthesis, structure and properties of metal complexes. He is an author of over 120 papers mostly on transition or post transition metal compounds. Currently retired he continues to carry out research as professor emeritus at York University.

Published/Copyright: April 30, 2013

Abstract

Four hundred and twenty monomeric organoplatinum compounds, in which platinum atoms are five- and higher coordinated, are analyzed. The platinum atoms are found in the oxidation states +2, +3 and +4. The Pt(II) compounds by far prevail. There are wide varieties of the inner coordination spheres about the platinum centers. The Pt(II) compounds are five-coordinated (trigonal bipyramidal and square pyramidal), six-coordinated (different degrees of distortion), seven-coordinated (pentagonal bipyramidal, piano stool) and sandwiched (PtC10). The Pt(III) compound is square-planar. The Pt(IV) compounds are six- and eight-coordinated. There are several relationships between the Pt-L bond distances, covalent radii of the coordinated atom/ligand, and metallocycles, which are discussed. The trans-effect plays an important role in the inner coordination spheres about the Pt centers, especially on the Pt-L bond distances.


Corresponding author: Milan Melník, Slovak Technical University, Inorganic Chemistry, Radlinskeho 9 Bratislava 812 37, Slovakia

About the authors

Milan Melník

Prof. Dr. Milan Melník, DrSc graduated from the Comenius University of Bratislava, Slovakia and obtained his PhD (1972) and Doctor of Science (1990) from Slovak Technical University (Slovakia). His main research interest concerns the coordination and bio-coordination chemistry of the transition and main group elements. In his research activities are structure – properties – bioactivities. His research focused on development new drugs on the basis of copper complex – antirheumatics, antituberculotics, with bioactive ligands. He has (co)authored 59 scientific monographs, over 350 scientific papers. He is a member of various universities and leading scientist of many research projects.

Peter Mikuš

Assoc. Prof. Dr. Peter Mikuš, PhD received his MSc in Analytical Chemistry in 1995 from the Faculty of Natural Sciences Comenius University in Bratislava, Slovak Republic. He received his PhD in Analytical Chemistry from the same Faculty in 2002. Currently, he is Assistant Professor, Head of the Department of Pharmaceutical Analysis and Nuclear Pharmacy and Director of the Toxicological and Antidoping Center. His research interests include development of new progressive (chiral) capillary electrophoresis separation methods for the advanced pharmaceutical and biomedical analyses of drugs, their (bio) degradation products, and biomarkers. Recently his research is also oriented on the crystallography of coordination compounds.

Clive Eduard Holloway

Professor Holloway obtained a MSc and PhD at the University of Western Ontario, and joined the Department of Chemistry, York University, Toronto, Canada in 1968. Research has included the synthesis, structure and properties of metal complexes. He is an author of over 120 papers mostly on transition or post transition metal compounds. Currently retired he continues to carry out research as professor emeritus at York University.

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Received: 2013-2-5
Accepted: 2013-3-15
Published Online: 2013-04-30
Published in Print: 2013-05-01

©2013 by Walter de Gruyter Berlin Boston

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