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Synthesis, parameters, properties and applications of responsive molecularly imprinted microgels: a review

  • Burhan Ullah

    Burhan Ullah: Burhan Ullah obtained his MSc in chemistry in 2017 from the University of Agriculture (Faisalabad, Pakistan). He has completed his MPhil degree in 2019 under the supervision of Shanza Rauf Khan.

    , Shanza Rauf Khan

    Shanza Rauf Khan: Shanza Rauf Khan obtained her MSc degree in chemistry in 2012 from the Institute of Chemistry, University of the Punjab (Lahore, Pakistan). She stood top in the MSc exam and was awarded a gold medal. In 2015, she completed her MPhil degree in physical chemistry with distinction. She has been working as a lecturer at the Department of Chemistry, University of Agriculture (Faisalabad, Pakistan), since 2015. Currently she is also pursuing her PhD studies.

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    , Sarmed Ali

    Sarmed Ali: Sarmed Ali obtained his MSc in physics from University of Gujrat in 2014. He has completed MPhil in physics in 2016 from Department of Physics, University of Agriculture (Faisalabad, Pakistan). Currently he is a visiting faculty member at University of Central Punjab and doing research in collaboration with University of Agriculture.

    and Saba Jamil

    Saba Jamil obtained her PhD from China in Materials Science in 2013. She is working as an assistant professor at University of Agriculture (Faisalabad, Pakistan) since 2015. Currently she is at Cornell University (Ittahaca, USA) on a FullBright Post Doc Fellowship.

Published/Copyright: February 19, 2021
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Abstract

Responsive molecularly imprinted microgels (MIGs) have gained a lot of interest due to their responsive specificity and selectivity for target compounds. Study on MIGs is rapidly increasing due to their quick responsive behavior in various stimuli like pH and temperature. MIGs show unique property of morphology control on in-situ synthesis of nanoparticles in response of variation in reactant concentration. Literature related to synthesis, parameters, characterization, applications and prospects of MIGs are critically reviewed here. Range of templates, monomers, initiators and crosslinkers are summarized for designing of desired MIGs. This review article describes effect of variation in reactants combination and composition on morphology, imprinting factor and percentage yield of MIGs. Hydrolysis of similar templates using MIGs is also described. Relation between percentage hydrolysis and hydrolysis time of targets at different temperatures and template:monomer ratio is also analyzed. Possible imprinting modes of ionic/non-ionic templates and its series are also generalized on the basis of previous literature. MIGs are investigated as efficient anchoring vehicles for adsorption, catalysis, bio-sensing, drug delivery, inhibition and detection.


Corresponding author: Shanza Rauf Khan, Department of Chemistry, University of Agriculture, Faisalabad 38000, Pakistan, E-mail:

About the authors

Burhan Ullah

Burhan Ullah: Burhan Ullah obtained his MSc in chemistry in 2017 from the University of Agriculture (Faisalabad, Pakistan). He has completed his MPhil degree in 2019 under the supervision of Shanza Rauf Khan.

Shanza Rauf Khan

Shanza Rauf Khan: Shanza Rauf Khan obtained her MSc degree in chemistry in 2012 from the Institute of Chemistry, University of the Punjab (Lahore, Pakistan). She stood top in the MSc exam and was awarded a gold medal. In 2015, she completed her MPhil degree in physical chemistry with distinction. She has been working as a lecturer at the Department of Chemistry, University of Agriculture (Faisalabad, Pakistan), since 2015. Currently she is also pursuing her PhD studies.

Sarmed Ali

Sarmed Ali: Sarmed Ali obtained his MSc in physics from University of Gujrat in 2014. He has completed MPhil in physics in 2016 from Department of Physics, University of Agriculture (Faisalabad, Pakistan). Currently he is a visiting faculty member at University of Central Punjab and doing research in collaboration with University of Agriculture.

Saba Jamil

Saba Jamil obtained her PhD from China in Materials Science in 2013. She is working as an assistant professor at University of Agriculture (Faisalabad, Pakistan) since 2015. Currently she is at Cornell University (Ittahaca, USA) on a FullBright Post Doc Fellowship.

Acknowledgments

The authors are highly thankful to Department of Chemistry, University of Agriculture Faisalabad, Faisalabad, Pakistan.

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Conflict of interest statement: The authors declare to have no conflicts of interest regarding this article.

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Supplementary Material

The online version of this article offers supplementary material (https://doi.org/10.1515/revce-2020-0030).


Received: 2020-05-10
Accepted: 2020-12-14
Published Online: 2021-02-19
Published in Print: 2022-08-26

© 2021 Walter de Gruyter GmbH, Berlin/Boston

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