Ac, La, and Ce radioimpurities in 225Ac produced in 40–200 MeV proton irradiations of thorium
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Jonathan W. Engle
,
John W. Weidner
Abstract
Accelerator production of 225Ac addresses the global supply deficiency currently inhibiting clinical trials from establishing 225Ac's therapeutic utility, provided that the accelerator product is of sufficient radionuclidic purity for patient use. Two proton activation experiments utilizing the stacked foil technique between 40 and 200 MeV were employed to study the likely co-formation of radionuclides expected to be especially challenging to separate from 225Ac. Foils were assayed by nondestructive γ-spectroscopy and by α-spectroscopy of chemically processed target material. Nuclear formation cross sections for the radionuclides 226Ac and 227Ac as well as lower lanthanide radioisotopes 139Ce, 141Ce, 143Ce, and 140La whose elemental ionic radii closely match that of actinium were measured and are reported. The predictions of the latest MCNP6 event generators are compared with measured data, as they permit estimation of the formation rates of other radionuclides whose decay emissions are not clearly discerned in the complex spectra collected from 232Th(p,x) fission product mixtures.
©2014 Walter de Gruyter Berlin/Boston
Articles in the same Issue
- Frontmatter
- Measurement of the 240Am production cross section via proton irradiation of 242Pu
- Ac, La, and Ce radioimpurities in 225Ac produced in 40–200 MeV proton irradiations of thorium
- Experimental cross section for the 152Sm(n, γ)153Sm reaction at 0.0334 eV
- Evaluation of an extraction chromatographic resin containing CMPO and ionic liquid for actinide ion uptake from acidic feeds: Part II. Batch actinide sorption, radiolytic degradation and column studies
- Single-cycle method for partitioning of trivalent actinides using completely incinerable reagents from nitric acid medium
- New unsymmetrical digycolamide ligands for trivalent actinide separation
- Extraction and stripping behaviour of tri-iso-amyl phosphate and tri-n-butyl phosphate in n-dodecane with U(VI) in nitric acid media
- Influence of humic acid on plutonium sorption to gibbsite: Determination of Pu-humic acid complexation constants and ternary sorption studies
- Sorption of cesium in young till soils
- Development of radiolanthanide labeled porphyrin complexes as possible therapeutic agents in beast carcinoma xenografts
Articles in the same Issue
- Frontmatter
- Measurement of the 240Am production cross section via proton irradiation of 242Pu
- Ac, La, and Ce radioimpurities in 225Ac produced in 40–200 MeV proton irradiations of thorium
- Experimental cross section for the 152Sm(n, γ)153Sm reaction at 0.0334 eV
- Evaluation of an extraction chromatographic resin containing CMPO and ionic liquid for actinide ion uptake from acidic feeds: Part II. Batch actinide sorption, radiolytic degradation and column studies
- Single-cycle method for partitioning of trivalent actinides using completely incinerable reagents from nitric acid medium
- New unsymmetrical digycolamide ligands for trivalent actinide separation
- Extraction and stripping behaviour of tri-iso-amyl phosphate and tri-n-butyl phosphate in n-dodecane with U(VI) in nitric acid media
- Influence of humic acid on plutonium sorption to gibbsite: Determination of Pu-humic acid complexation constants and ternary sorption studies
- Sorption of cesium in young till soils
- Development of radiolanthanide labeled porphyrin complexes as possible therapeutic agents in beast carcinoma xenografts
