Excitation function of (p, α) nuclear reaction on enriched 67Zn: possibility of production of 64Cu at low energy cyclotron
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Ferenc Szelecsényi
,
Zoltán Kovács
Abstract
The potential for production of the medically relevant 64Cu has been investigated by proton irradiation of highly enriched 67Zn targets. The excitation function of the 67Zn(p, α)64Cu a nuclear reaction was measured by the stacked-foil technique up to 30 MeV. The prediction of the TALYS code was also compared to the measured cross section results. Based on the improved database of the 67Zn(p, α)64Cu reaction, thick target yield as a function of energy was also deduced. Production possibility of 64Cu is discussed in detail, employing different energy proton beams and with regards to the 61Cu and 67Cu contamination levels as a function of the target enrichment level. By using 1 μA beam intensity, 6.3505 h irradiation time and enriched 67Zn target (64Zn ≤ 0.5%, 66Zn ≤ 9%, 67Zn ≥ 80%, 68Zn ≤ 10% and 70Zn ≤ 0.5%), the expected EOB (End Of bombardment) yields are 43.66, 88.80 and 156.14 MBq/μA at 12, 15 and 18 MeV proton energies, respectively. Application time-frames were also deduced where the total radio-copper contamination level remains below 1%.
©2014 Walter de Gruyter Berlin/Boston
Articles in the same Issue
- Frontmatter
- Excitation function of (p, α) nuclear reaction on enriched 67Zn: possibility of production of 64Cu at low energy cyclotron
- Radiochemical measurement of neutron-spectrum averaged cross sections for the formation of 64Cu and 67Cu via the (n,p) reaction at a TRIGA Mark-II reactor: Feasibility of simultaneous production of the theragnostic pair 64Cu/67Cu
- A novel dipicolinamide-dicarbollide synergistic solvent system for actinide extraction
- Plutonium sorption to nanocast mesoporous carbon
- Retrieval and purification of an aged 231Pa source from its decay daughters
- Natural radioactivity measurements in agricultural soil, fertilizer and crops in some specific areas of Kingdom of Saudi Arabia
- Utilization of a novel electrochemical 90Sr/90Y generator for the preparation of 90Y-labeled RGD peptide dimer in clinically relevant dose
- Radiochemical synthesis and biological evaluation of 3-[4-(4-[18F]fluorobenzyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine as dopamine D4 receptor radioligand
- Synthesis and initial biological evaluation of a novel Tc-99m radioligand as a potential agent for 5-HT1A receptor imaging
- Clinical scale preparation and evaluation of 131I-Rituximab for Non-Hodgkin's Lymphoma
Articles in the same Issue
- Frontmatter
- Excitation function of (p, α) nuclear reaction on enriched 67Zn: possibility of production of 64Cu at low energy cyclotron
- Radiochemical measurement of neutron-spectrum averaged cross sections for the formation of 64Cu and 67Cu via the (n,p) reaction at a TRIGA Mark-II reactor: Feasibility of simultaneous production of the theragnostic pair 64Cu/67Cu
- A novel dipicolinamide-dicarbollide synergistic solvent system for actinide extraction
- Plutonium sorption to nanocast mesoporous carbon
- Retrieval and purification of an aged 231Pa source from its decay daughters
- Natural radioactivity measurements in agricultural soil, fertilizer and crops in some specific areas of Kingdom of Saudi Arabia
- Utilization of a novel electrochemical 90Sr/90Y generator for the preparation of 90Y-labeled RGD peptide dimer in clinically relevant dose
- Radiochemical synthesis and biological evaluation of 3-[4-(4-[18F]fluorobenzyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine as dopamine D4 receptor radioligand
- Synthesis and initial biological evaluation of a novel Tc-99m radioligand as a potential agent for 5-HT1A receptor imaging
- Clinical scale preparation and evaluation of 131I-Rituximab for Non-Hodgkin's Lymphoma
