In 1989, the journal Pteridines was initiated as the official periodical of the International Society of Pteridinology (ISP), 100 years after the first publication on pteridines by Nobel laureate Sir Gowland Hopkins (Proceedings of the Chemical Society 1989;5:117). Currently, Pteridines is in its 24th year of publication. The journal is devoted to bridging the gap between basic, chemical and clinical aspects of pteridines and publishes work in the fields of Unconjugated and Conjugated Pteridines, Biochemistry of Pteridines, Chemistry of Pteridines and Clinical Chemistry of Pteridines.
The founders of the journal were Professor Wolfgang Pfleiderer, Konstanz, Germany (see publication list published in Pteridines 1998;9:123–38) and Professor Helmut Wachter, Innsbruck, Austria (†2012, see obituary published in Pteridines 2012;23:1 and a summary of his achievements on the occasion of his 80th birthday published in Pteridines 2009;20:113–4). Professor John A. Blair, Birmingham, UK (†2000, see obituary published in Pteridines 2000;11:73–5) was the first Editor-in-Chief.
Initially, Pteridines was published by De Gruyter, Berlin, Germany. In 1993, Jeongbin Yim, Seoul, Republic of Korea took over the Chief Editorship and the journal continued to be published by the Korean company Han-lim Printing Co. until 2000. Thereafter, Dr. Vojtech Parrak, Bratislava, Slovak Republic took charge of Pteridines. By the end of 2006, the production of the printed version of the journal was suspended and a web-based publication was launched. Starting in 2013, De Gruyter re-entered to publish the journal, and in addition to the online publication a print-on-demand version will become available. At the same time, Professor Dietmar Fuchs, Innsbruck, Austria has accepted responsibility as Editor-in-Chief of Pteridines.
Papers, reviews, mini-reviews, commentaries and opinions on controversial subjects will be published regularly. Online processing (http://mc.manuscriptcentral.com/dgpterid)will guarantee competent and fair reviewing, as well as fast and high quality publication. Rapid evaluation of manuscripts will be performed, and every effort will be made to ensure that decisions on submitted manuscripts are available within 4 weeks. There are no page charges and no charges for color figures. Accepted papers are published ahead of print in an accelerated online-only format for immediate visibility within the scientific community: Please see www.degruyter.com/view/j/pteridines.
This first issue of Pteridines (volume 24) contains 19 articles based on presentations delivered at the 15th International Symposium on Pteridines and Folates, held in Antalya, Turkey, May 9–13, 2012. It provides an overview of the whole field of current research on pteridines, which includes conjugated pteridines like folates and unconjugated pteridines like 5,6,7,8-tetrahydrobiopterin and neopterin, molybdopterin and their corresponding enzyme networks.
With the additional input of an experienced publishing house and the support of international researchers in the field, we are convinced that the new format and organization of Pteridines will contribute to its improved visibility and thus help to further the journal’s reputation within the international scientific community.
©2013 by Walter de Gruyter Berlin Boston
Articles in the same Issue
- Masthead
- Masthead
- Editorial
- New developments in the publication of Pteridines
- Chemistry
- First synthesis of asperopterin A, an isoxanthopterin glycoside from Aspergillus oryzae
- Tetrahydrobiopterin
- Three classes of tetrahydrobiopterin-dependent enzymes
- Tetrahydrobiopterin attenuates ischemia-reperfusion injury following organ transplantation by targeting the nitric oxide synthase: investigations in an animal model
- Inflammatory diseases
- Folates and antifolates in rheumatoid arthritis
- Immune activation and inflammation increase the plasma phenylalanine-to-tyrosine ratio
- Tryptophan degradation and neopterin levels by aging
- Spot analyses of serum neopterin, tryptophan and kynurenine levels in a random group of blood donor population
- Endothelial dysfunction, cardiovascular diseases
- Tetrahydrobiopterin protects soluble guanylate cyclase against oxidative inactivation
- Immune activation and inflammation in patients with cardiovascular disease are associated with elevated phenylalanine-to-tyrosine ratios
- Malignant diseases treatment
- Thymidylate synthase inhibitors for thoracic tumors
- Polymorphisms correlated with the clinical outcome of locally advanced or metastatic colorectal cancer patients treated with ALIRI vs. FOLFIRI
- Folate homeostasis of cancer cells affects sensitivity to not only antifolates but also other non-folate drugs: effect of MRP expression
- Enzymology folates
- Crystal structures of thymidylate synthase from nematodes, Trichinella spiralis and Caenorhabditis elegans, as a potential template for species-specific drug design
- Crystal structures of complexes of mouse thymidylate synthase crystallized with N4-OH-dCMP alone or in the presence of N5,10-methylenetetrahydrofolate
- Enzymology pterins
- First insights into structure-function relationships of alkylglycerol monooxygenase
- Fatty aldehyde dehydrogenase, the enzyme downstream of tetrahydrobiopterin-dependent alkylglycerol monooxygenase
- Expression of full-length human alkylglycerol monooxygenase and fragments in Escherichia coli
- Enzyme occurrence and function in model organisms
- The diverse biological functions of glutathione S-transferase omega in Drosophila
- Uncommon and parallel developmental patterns of thymidylate synthase expression and localization in Trichinella spiralis and Caenorhabditis elegans
Articles in the same Issue
- Masthead
- Masthead
- Editorial
- New developments in the publication of Pteridines
- Chemistry
- First synthesis of asperopterin A, an isoxanthopterin glycoside from Aspergillus oryzae
- Tetrahydrobiopterin
- Three classes of tetrahydrobiopterin-dependent enzymes
- Tetrahydrobiopterin attenuates ischemia-reperfusion injury following organ transplantation by targeting the nitric oxide synthase: investigations in an animal model
- Inflammatory diseases
- Folates and antifolates in rheumatoid arthritis
- Immune activation and inflammation increase the plasma phenylalanine-to-tyrosine ratio
- Tryptophan degradation and neopterin levels by aging
- Spot analyses of serum neopterin, tryptophan and kynurenine levels in a random group of blood donor population
- Endothelial dysfunction, cardiovascular diseases
- Tetrahydrobiopterin protects soluble guanylate cyclase against oxidative inactivation
- Immune activation and inflammation in patients with cardiovascular disease are associated with elevated phenylalanine-to-tyrosine ratios
- Malignant diseases treatment
- Thymidylate synthase inhibitors for thoracic tumors
- Polymorphisms correlated with the clinical outcome of locally advanced or metastatic colorectal cancer patients treated with ALIRI vs. FOLFIRI
- Folate homeostasis of cancer cells affects sensitivity to not only antifolates but also other non-folate drugs: effect of MRP expression
- Enzymology folates
- Crystal structures of thymidylate synthase from nematodes, Trichinella spiralis and Caenorhabditis elegans, as a potential template for species-specific drug design
- Crystal structures of complexes of mouse thymidylate synthase crystallized with N4-OH-dCMP alone or in the presence of N5,10-methylenetetrahydrofolate
- Enzymology pterins
- First insights into structure-function relationships of alkylglycerol monooxygenase
- Fatty aldehyde dehydrogenase, the enzyme downstream of tetrahydrobiopterin-dependent alkylglycerol monooxygenase
- Expression of full-length human alkylglycerol monooxygenase and fragments in Escherichia coli
- Enzyme occurrence and function in model organisms
- The diverse biological functions of glutathione S-transferase omega in Drosophila
- Uncommon and parallel developmental patterns of thymidylate synthase expression and localization in Trichinella spiralis and Caenorhabditis elegans