Synthesis of biopolymer-polypeptide conjugates and their potential therapeutic interests
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Amandeep Singh
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Kamlesh Kumari
Abstract
Biopolymer-based conjugates are widely used for numbers of biomedical applications. Materials scientists have become progressively interested in compounding biological-relevant entities with biopolymers into polymeric biohybrid framework. Biopolymer are conjugated with various fragments such as enzymes, proteins, nucleic acids as well as their analogues, peptidomimetics, peptides, fluorescent composites, avidin or streptavidin, biotin, polyethylene glycol, and various other bioactive compounds in order to serve a particular functionality in biomedical applications. In current chapter, a summary of various methods to synthesize biopolymer-peptide biohybrid conjugates and their prospective applications in biomedical field is presented.
Acknowledgments
The authors would like to thank the editors Swati Sharma and Ashok Kumar Nadda for their guidance and review of this article before its publication.
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Research ethics: Proper acknowledgment of the work of others is given by citations. Rights for the contents (figures) were taken through copyright permission platform ‘RightsLink’ and acknowledgment is given through citations.
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Author contributions: The authors have accepted responsibility for the entire content of this manuscript and approved its submission.
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Competing interests: The authors state no conflict of interest.
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Research funding: Amandeep Singh like to thank Department of Science and Technology (DST), Government of India, for providing the DST-INSPIRE fellowship (IF 140804).
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Data availability: Not applicable.
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Articles in the same Issue
- Frontmatter
- Reviews
- Circular plastics technologies: open loop recycling of waste plastics into new chemicals
- Biopolymeric conjugation with synthetic fibers and applications
- Antibody biopolymer conjugate
- Intensification of biocatalytic processes by using alternative reaction media
- Biopolymeric conjugation with food additives
- Bioprocess intensification with model-assisted DoE-strategies for the production of biopharmaceuticals
- Synthesis of biopolymer-polypeptide conjugates and their potential therapeutic interests
- Future perspectives of biopolymeric industry
- Process intensification in biopharmaceutical process development and production – an industrial perspective
- Citric acid: fermentative production using organic wastes as feedstocks
Articles in the same Issue
- Frontmatter
- Reviews
- Circular plastics technologies: open loop recycling of waste plastics into new chemicals
- Biopolymeric conjugation with synthetic fibers and applications
- Antibody biopolymer conjugate
- Intensification of biocatalytic processes by using alternative reaction media
- Biopolymeric conjugation with food additives
- Bioprocess intensification with model-assisted DoE-strategies for the production of biopharmaceuticals
- Synthesis of biopolymer-polypeptide conjugates and their potential therapeutic interests
- Future perspectives of biopolymeric industry
- Process intensification in biopharmaceutical process development and production – an industrial perspective
- Citric acid: fermentative production using organic wastes as feedstocks
